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Aria F. Olumi, MD

Associate Professor, Department of Surgery, Harvard Medical School

Director, Urology Research Program, Genitourinary Oncology Unit, Massachusetts General Hospital

Contact Info

Aria Olumi
Massachusetts General Hospital
55 Fruit Street
Boston, MA, 02114
Mailstop: Yawkey, Suite 7E
Phone: 617-643-0237
Fax: 617-643-4019
aolumi@partners.org

Assistant

Francine O'Reilly
Administrative Assistant
Urology
Massachusetts General Hospital
55 Fruit St.
Boston, MA, 02114
Phone: 617-643-0237
Fax: 617-643-4019
foreilly@partners.org

DF/HCC Program Affiliation

Kidney Cancer
Prostate Cancer

Research Abstract

TRAIL, a recently discovered member of the TNF superfamily of cytokines, may be a useful apoptotic-inducing treatment for prostate cancer. However, better understanding the molecular pathways that render a cell TRAIL-sensitive (PC3 and DU145 cells) vs. TRAIL-resistant (LNCaP cells) is crucial in order to selectively offer TRAIL to patients who would maximally benefit from the drug. The focus of my lab is to delineate the molecular mechanisms between TRAIL-resistant and TRAIL-sensitive prostate cancer cells.

Publications

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