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Stuart H. Orkin, M.D.

David G. Nathan Professor of Pediatrics, Department of Pediatrics, Harvard Medical School

Chairman, Pediatric Oncology, Dana-Farber Cancer Institute

Investigator, Pediatrics, Children's Hospital Boston

Contact Info

Stuart Orkin
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA, 02115
Mailstop: Dana 1640
Phone: 617-632-3564
Fax: 617-632-4367
stuart_orkin@dfci.harvard.edu

Assistant

Marie Palardy
Children's Hospital Boston
300 Longwood Avenue
Boston, MA, 02115
Phone: 617-919-2042
Fax: 617-730-0222
palardy@bloodgroup.tch.harvard.edu

DF/HCC Program Affiliation

Leukemia

Research Abstract

1. Molecular genetics and biology of human disease
2. Thalassemia syndromes and hemoglobin synthesis
3. Prenatal diagnosis of genetic disease
4. Molecular genetics and biochemistry of the phagocytic cell
5. Gene transfer and expression in hematopoietic cells
6. Hematopoietic cell development

Publications

  • Ackerman KG, Wang J, Luo L, Fujiwara Y, Orkin SH, Beier DR.Gata4 is necessary for normal pulmonary lobar development.Am J Respir Cell Mol Biol 2007 Apr;36(4):391-7.
    17142311
  • Wang LC, Swat W, Fujiwara Y, Davidson L, Visvader J, Kuo F, Alt FW, Gilliland DG, Golub TR, Orkin SH.The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow.Genes Dev 1998 Aug 1;12(15):2392-402.
    9694803
  • Wang LC, Kuo F, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH.Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL.EMBO J 1997 Jul 16;16(14):4374-83.
    9250681