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Dana H. Gabuzda, MD

Professor, Department of Neurology, Harvard Medical School

Associate Physician, Neurology, Brigham And Women's Hospital

Professor of Neurology (Microbiology), Cancer Immunology/AIDS, Dana-Farber Cancer Institute

Contact Info

Dana Gabuzda
Dana-Farber Cancer Institute
CLS 1008

Boston, MA, 02215
Mailstop: CLS 1010
Phone not available.
Email not available


Elizabeth Carpelan
Administrative Assistant
Cancer Immunology/AIDS
Dana-Farber Cancer Institute
450 Brookline AVenue
Boston, MA, 02215
Mailstop: CLS 1010
Phone: 617-632-4332

DF/HCC Program Affiliation

Cancer Immunology

Research Abstract

The major research interest of the Gabuzda lab is to understand molecular mechanisms of HIV replication and pathogenesis, and their implications for understanding pathogen-host interactions, immune responses, and disease outcomes. Using biological, genetic, biochemical, and systems biology approaches, we study: 1) HIV replication and pathogenesis in the immune system and central nervous system; 2) mechanisms and pathways underlying differences in host responses to viral infection and antiretroviral therapy; 3) viral diversity and tropism for specific cell types and tissues; 4) functions of the HIV Env, Vif, and Nef proteins; 5) high-throughput screening assays to identify small molecules that inhibit Vif interaction with its host cell cofactor APOBEC3G.


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