Pier Paolo Pandolfi, M.D. Ph.D.

Professor of Medicine and Pathology, Department of Medicine, Harvard Medical School

Director, Cancer and Genetics Program, BIDMC Cancer Center, Medicine and Pathology, Beth Israel Deaconess Medical Center

Chief, Division of Genetics, Medicine, Beth Israel Deaconess Medical Center

Associate Director for Basic Science, BIDMC Cancer Center, Medicine and Pathology, Beth Israel Deaconess Medical Center

Contact Info

Pier Paolo Pandolfi
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA, 02215
Mailstop: NRB 1036E
Phone: 617-667-6884
Fax: 617-667-3330
ppandolf@bidmc.harvard.edu

Assistant

Thomas Naughton
Administrative Coordinator
Beth Israel Deaconess Medical Center
Phone: 617-735-2145
Fax: 617-735-2120
tnaughto@bidmc.harvard.edu

DF/HCC Program Affiliation

Leukemia, Co-Leader
Prostate Cancer

DF/HCC Associations

Member, Center Scientific Council

Research Abstract

The Pandolfi laboratory focuses on elucidating the molecular mechanisms and the genetics underlying the pathogenesis of leukemias, lymphomas and solid tumors as well as in modeling these cancers in the mouse. Dr. Pandolfi and colleagues have characterized the function of the fusion oncoproteins and the genes involved in the chromosomal translocations of acute promyelocytic leukemia (APL), as well as of major tumor suppressors such PTEN and p53 and novel proto-oncogenes such POKEMON. The elucidation of the molecular basis underlying APL pathogenesis has led to the development of novel and effective therapeutic strategies. As a result of these efforts, APL is now considered a curable disease. Novel therapeutic concepts have emerged from this work that are currently being tested in clinical trials.

Publications

No representative citations available.

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DF/HCC Directory Login Update Member Profile Change Account Settings Applying for Membership Benefits Requirements Responsibilities	Pier Paolo Pandolfi, M.D. Ph.D. Professor of Medicine and Pathology, Department of Medicine, Harvard Medical School Director, Cancer and Genetics Program, BIDMC Cancer Center, Medicine and Pathology, Beth Israel Deaconess Medical Center Chief, Division of Genetics, Medicine, Beth Israel Deaconess Medical Center Associate Director for Basic Science, BIDMC Cancer Center, Medicine and Pathology, Beth Israel Deaconess Medical Center Contact Info Pier Paolo Pandolfi Beth Israel Deaconess Medical Center 330 Brookline Avenue Boston, MA, 02215 Mailstop: NRB 1036E Phone: 617-667-6884 Fax: 617-667-3330 ppandolf@bidmc.harvard.edu Assistant Thomas Naughton Administrative Coordinator Beth Israel Deaconess Medical Center Phone: 617-735-2145 Fax: 617-735-2120 tnaughto@bidmc.harvard.edu DF/HCC Program Affiliation Leukemia, Co-Leader Prostate Cancer DF/HCC Associations Member, Center Scientific Council Research Abstract The Pandolfi laboratory focuses on elucidating the molecular mechanisms and the genetics underlying the pathogenesis of leukemias, lymphomas and solid tumors as well as in modeling these cancers in the mouse. Dr. Pandolfi and colleagues have characterized the function of the fusion oncoproteins and the genes involved in the chromosomal translocations of acute promyelocytic leukemia (APL), as well as of major tumor suppressors such PTEN and p53 and novel proto-oncogenes such POKEMON. The elucidation of the molecular basis underlying APL pathogenesis has led to the development of novel and effective therapeutic strategies. As a result of these efforts, APL is now considered a curable disease. Novel therapeutic concepts have emerged from this work that are currently being tested in clinical trials. Publications No representative citations available.
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