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Philip Leder, M.D.

John Emory Andrus Professor of Genetics, Department of Genetics, Harvard Medical School

Contact Info

Philip Leder
Harvard Medical School
200 Longwood Avenue
Boston, MA, 02115
Mailstop: Room 538
Phone: 617-432-7667
Fax: 617-432-7944
leder@rascal.med.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Cancer Genetics
Breast Cancer

Research Abstract

Not Available.

Publications

  • Lu J, Ruhf ML, Perrimon N, Leder P.A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.Proc Natl Acad Sci U S A 2007 May 29;104(22):9381-6.
    17517653
  • Babbe H, Chester N, Leder P, Reizis B.The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.Mol Cell Biol 2007 Mar;27(5):1947-59.
    17210642
  • Chester N, Babbe H, Pinkas J, Manning C, Leder P.Mutation of the murine Bloom's syndrome gene produces global genome destabilization.Mol Cell Biol 2006 Sep;26(17):6713-26.
    16914751
  • Fantin VR, Leder P.Mitochondriotoxic compounds for cancer therapy.Oncogene 2006 Aug 7;25(34):4787-97.
    16892091
  • Zhou F, Leder P, Martin SS.Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.Exp Cell Res 2006 Apr 15;312(7):1119-26.
    16480715
  • Ridgeway AG, McMenamin J, Leder P.P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.Oncogene 2006 Jun 15;25(25):3518-27.
    16434961
  • Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P.The death domain kinase RIP mediates the TNF-induced NF-kappaB signal.Immunity 1998 Mar;8(3):297-303.
    9529147