Charles Lee, Ph.D.
Associate Professor, Department of Pathology, Harvard Medical School
Cytogeneticist, Cytogenetics Laboratory, Brigham And Women's Hospital
Contact Info
Charles Lee
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Mailstop: EBRC 404A
Phone: 617-278-0031
Fax: 617-264-5176
clee@rics.bwh.harvard.edu
Administrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
20 Shattuck Street
Boston, MA, 02115
Phone: 617-525-8360
Fax: 617-264-5176
shislop@partners.org
Victoria Banchevsky
Administrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Phone: 617-525-8576
Fax: 617-264-5176
vbanchevsky@partners.org
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Mailstop: EBRC 404A
Phone: 617-278-0031
Fax: 617-264-5176
clee@rics.bwh.harvard.edu
Assistant
Shona HislopAdministrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
20 Shattuck Street
Boston, MA, 02115
Phone: 617-525-8360
Fax: 617-264-5176
shislop@partners.org
Victoria Banchevsky
Administrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Phone: 617-525-8576
Fax: 617-264-5176
vbanchevsky@partners.org
DF/HCC Program Affiliation
Cancer GeneticsDF/HCC Associations
Director, CytogeneticsMember, Center Scientific Council
Research Abstract
http://www.chromosome.bwh.harvard.eduMy research focus is the application of classical cytogenetics and multicolor fluorescence in situ hybridization technologies to dissect genomic rearrangements that occur during tumor development in humans and mouse. Chromosomal rearrangements can indicate genomic instability as well as define specific tumor types and progression.
Publications
- Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC.Diet and the evolution of human amylase gene copy number variation.Nat Genet 2007 Oct;39(10):1256-60.
17828263 - Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura
17122850 - Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, Cáceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C.Hotspots for copy number variation in chimpanzees and humans.Proc Natl Acad Sci U S A 2006 May 23;103(21):8006-11.
16702545 - Nadeau JH, Lee C.Genetics: copies count.Nature 2006 Feb 16;439(7078):798-9.
16482142 - McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, Altshuler DM,.Common deletion polymorphisms in the human genome.Nat Genet 2006 Jan;38(1):86-92.
16468122 - Lee C.Vive la difference!.Nat Genet 2005 Jul;37(7):660-1.
15990882 - Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C.Detection of large-scale variation in the human genome.Nat Genet 2004 Aug 01;19:1-3.
- Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, Peters LL, Chernova MN, Alper SL, Zapata A, Wickramasinghe SN, Lee MJ, Lux SE, Fritz A, Postlethwait JH, Zon LI.Cell-




