Charles Lee, Ph.D.

Associate Professor, Department of Pathology, Harvard Medical School

Cytogeneticist, Cytogenetics Laboratory, Brigham And Women's Hospital

Contact Info

Charles Lee
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Mailstop: EBRC 404A
Phone: 617-278-0031
Fax: 617-264-5176
clee@rics.bwh.harvard.edu

Assistant

Shona Hislop
Administrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
20 Shattuck Street
Boston, MA, 02115
Phone: 617-525-8360
Fax: 617-264-5176
shislop@partners.org
Victoria Banchevsky
Administrative Assistant
Cytogenetics Laboratory
Brigham And Women's Hospital
221 Longwood Avenue
Boston, MA, 02115
Phone: 617-525-8576
Fax: 617-264-5176
vbanchevsky@partners.org

DF/HCC Program Affiliation

Cancer Genetics

DF/HCC Associations

Director, Cytogenetics
Member, Center Scientific Council

Research Abstract

http://www.chromosome.bwh.harvard.edu

My research focus is the application of classical cytogenetics and multicolor fluorescence in situ hybridization technologies to dissect genomic rearrangements that occur during tumor development in humans and mouse. Chromosomal rearrangements can indicate genomic instability as well as define specific tumor types and progression.

Publications

Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC.Diet and the evolution of human amylase gene copy number variation.Nat Genet 2007 Oct;39(10):1256-60.
17828263
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura
17122850
Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, Cáceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C.Hotspots for copy number variation in chimpanzees and humans.Proc Natl Acad Sci U S A 2006 May 23;103(21):8006-11.
16702545
Nadeau JH, Lee C.Genetics: copies count.Nature 2006 Feb 16;439(7078):798-9.
16482142
McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, Altshuler DM,.Common deletion polymorphisms in the human genome.Nat Genet 2006 Jan;38(1):86-92.
16468122
Lee C.Vive la difference!.Nat Genet 2005 Jul;37(7):660-1.
15990882
Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C.Detection of large-scale variation in the human genome.Nat Genet 2004 Aug 01;19:1-3.
Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, Peters LL, Chernova MN, Alper SL, Zapata A, Wickramasinghe SN, Lee MJ, Lux SE, Fritz A, Postlethwait JH, Zon LI.Cell-

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DF/HCC Directory Login Update Member Profile Change Account Settings Applying for Membership Benefits Requirements Responsibilities	Charles Lee, Ph.D. Associate Professor, Department of Pathology, Harvard Medical School Cytogeneticist, Cytogenetics Laboratory, Brigham And Women's Hospital Contact Info Charles Lee Brigham And Women's Hospital 221 Longwood Avenue Boston, MA, 02115 Mailstop: EBRC 404A Phone: 617-278-0031 Fax: 617-264-5176 clee@rics.bwh.harvard.edu Assistant Shona Hislop Administrative Assistant Cytogenetics Laboratory Brigham And Women's Hospital 20 Shattuck Street Boston, MA, 02115 Phone: 617-525-8360 Fax: 617-264-5176 shislop@partners.org Victoria Banchevsky Administrative Assistant Cytogenetics Laboratory Brigham And Women's Hospital 221 Longwood Avenue Boston, MA, 02115 Phone: 617-525-8576 Fax: 617-264-5176 vbanchevsky@partners.org DF/HCC Program Affiliation Cancer Genetics DF/HCC Associations Director, Cytogenetics Member, Center Scientific Council Research Abstract http://www.chromosome.bwh.harvard.edu My research focus is the application of classical cytogenetics and multicolor fluorescence in situ hybridization technologies to dissect genomic rearrangements that occur during tumor development in humans and mouse. Chromosomal rearrangements can indicate genomic instability as well as define specific tumor types and progression. Publications Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC.Diet and the evolution of human amylase gene copy number variation.Nat Genet 2007 Oct;39(10):1256-60. 17828263 Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura 17122850 Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, Cáceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C.Hotspots for copy number variation in chimpanzees and humans.Proc Natl Acad Sci U S A 2006 May 23;103(21):8006-11. 16702545 Nadeau JH, Lee C.Genetics: copies count.Nature 2006 Feb 16;439(7078):798-9. 16482142 McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, Altshuler DM,.Common deletion polymorphisms in the human genome.Nat Genet 2006 Jan;38(1):86-92. 16468122 Lee C.Vive la difference!.Nat Genet 2005 Jul;37(7):660-1. 15990882 Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C.Detection of large-scale variation in the human genome.Nat Genet 2004 Aug 01;19:1-3. Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, Peters LL, Chernova MN, Alper SL, Zapata A, Wickramasinghe SN, Lee MJ, Lux SE, Fritz A, Postlethwait JH, Zon LI.Cell-
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