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David T. Scadden, M.D.

Professor, Department of Medicine, Harvard Medical School

Director, Experimental Hematology, Massachusetts General Hospital

Director, Center for AIDS Oncology, Dana-Farber Cancer Institute

Contact Info

David Scadden
Massachusetts General Hospital
185 Cambridge Street
Boston, MA, 02114
Mailstop: CPZN-4265A
Phone: 617-726-5615
Fax: 617-724-2662
dscadden@mgh.harvard.edu

Assistant

Mary Lou McKeone
Executive Assistant
Experimental Hematology
Massachusetts General Hospital
185 Cambridge Street
Boston, MA, 02114
Mailstop: CPZN-4265A
Phone: 617-724-5780
Fax: 617-724-2662
mmckeone@partners.org

DF/HCC Program Affiliation

Leukemia, Co-Leader
Cancer Cell Biology
Cancer Immunology
Lymphoma and Myeloma

DF/HCC Associations

Member, Center Scientific Council

Research Abstract

The focus of the laboratory is hematopoietic stem cell biology emphasizing 1) cell cycle regulation, 2) lineage fate decisions, and 3) manipulation for stem cell-based therapies. The disease context in which these issues are being addressed is AIDS.

Publications

  • Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, Ivy P, Scadden DT, Benner T, Loeffler JS, Wen PY, Jain RK.AZD2171, a pan-VEGF receptor ty
    17222792
  • Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT.Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.Nature 2006 Sep 28;443(7110):421-6.
    16957735