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Steven Joffe, M.D. M.P.H.

Assistant Professor, Department of Pediatrics, Harvard Medical School

Attending Physician, Medicine, Children's Hospital Boston

Active Medical Staff, Pediatric Oncology, Dana-Farber Cancer Institute

Member, Center for Outcomes and Policy Research, Dana-Farber Cancer Institute

Contact Info

Steven Joffe
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA, 02115
Mailstop: Smith 207
Phone: 617-632-5295
Fax: 617-632-2270
steven_joffe@dfci.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Outcomes Research

Research Abstract

The major focus of my current work is the ethics of research involving human subjects. I conduct observational and intervention studies of informed consent to clinical trials. I also study how methodological and ethical considerations intersect in clinical trial design. I am interested in the implications of human subjects regulations for clinical research and drug development, and in how clinicians and investigators navigate their complex roles. Finally, I have a research interest in the doctor-patient relationship, and in how theoretical ethical models of health care relate to the actual practice of medicine.

Publications

  • Joffe S, Fernandez CV, Pentz RD, Ungar DR, Mathew NA, Turner CW, Alessandri AJ, Woodman CL, Singer DA, Kodish E.Involving children with cancer in decision-making about research participation.J Pediatr 2006 Dec;149(6):862-868.
    17137908
  • Hampson LA, Agrawal M, Joffe S, Gross CP, Verter J, Emanuel EJ.Patients' views on financial conflicts of interest in cancer research trials.N Engl J Med 2006 Nov 30;355(22):2330-7.
    17135586
  • Peppercorn JM, Weeks JC, Cook EF, Joffe S.Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review.Lancet 2004 Jan 24;363(9405):263-70.
    14751698
  • Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC.Quality of informed consent in cancer clinical trials: a cross-sectional survey.Lancet 2001 Nov 24;358(9295):1772-7.
    11734235