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Frederick G. Barker, M.D.

Associate Professor, Department of Surgery, Harvard Medical School

Associate Visiting Surgeon, Neurosurgery, Massachusetts General Hospital

Contact Info

Frederick Barker
Massachusetts General Hospital
55 Fruit Street
Boston, MA, 02114
Mailstop: Brain Tumor Center, Cox 3
Phone: 617-724-8772
Fax: 617-724-8769
barker@helix.mgh.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Neuro-Oncology

Research Abstract

Clinical research on glioblastoma multiforme and other malignant gliomas, including trial design for phase I gene therapy trials, prognostic variable studies, radiation response in correlation with molecular markers (EGFR)

Publications

  • Barker FG.Efficacy of prophylactic antibiotics against meningitis after craniotomy: a meta-analysis.Neurosurgery 2007 May;60(5):887-94; discussion 887-94.
    17460524
  • Ghogawala Z, Coumans JV, Benzel EC, Stabile LM, Barker FG.Ventral versus dorsal decompression for cervical spondylotic myelopathy: surgeons' assessment of eligibility for randomization in a proposed randomized controlled trial: results of a survey of the
    17304133
  • Pommier P, Liebsch NJ, Deschler DG, Lin DT, McIntyre JF, Barker FG, Adams JA, Lopes VV, Varvares M, Loeffler JS, Chan AW.Proton beam radiation therapy for skull base adenoid cystic carcinoma.Arch Otolaryngol Head Neck Surg 2006 Nov;132(11):1242-9.
    17116822
  • Ulmer S, Braga TA, Barker FG, Lev MH, Gonzalez RG, Henson JW.Clinical and radiographic features of peritumoral infarction following resection of glioblastoma.Neurology 2006 Nov 14;67(9):1668-70.
    17101902
  • Smith ER, Butler WE, Barker FG.Is there a "July phenomenon" in pediatric neurosurgery at teaching hospitals?.J Neurosurg 2006 Sep;105(3 Suppl):169-76.
    16970228
  • Barker FG.Brain metastasis.J Neurosurg 2006 Sep;105(3):371-2; discussion 372-4.
    16961128
  • Pelloski CE, Lin E, Zhang L, Yung WK, Colman H, Liu JL, Woo SY, Heimberger AB, Suki D, Prados M, Chang S, Barker FG, Fuller GN, Aldape KD.Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma.Clin Cancer Re
    16818690
  • Flickinger JC, Barker FG.Clinical results: radiosurgery and radiotherapy of cranial nerve schwannomas.Neurosurg Clin N Am 2006 Apr;17(2):121-8.
    16793504
  • Barker FG, Chang SM.Improving resection of malignant glioma.Lancet Oncol 2006 May;7(5):359-60.
    16648038
  • Aghi M, Kluwe L, Webster MT, Jacoby LB, Barker FG, Ojemann RG, Mautner VF, MacCollin M.Unilateral vestibular schwannoma with other neurofibromatosis type 2-related tumors: clinical and molecular study of a unique phenotype.J Neurosurg 2006 Feb;104(2):201-
    16509493
  • Aghi M, Gaviani P, Henson JW, Batchelor TT, Louis DN, Barker FG.Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma.Clin Cancer Res 2005 Dec 15;11(24 Pt 1):8600-5.
    16361543
  • Amin-Hanjani S, Butler WE, Ogilvy CS, Carter BS, Barker FG.Extracranial-intracranial bypass in the treatment of occlusive cerebrovascular disease and intracranial aneurysms in the United States between 1992 and 2001: a population-based study.J Neurosurg 2
    16304982
  • Curry WT, McDermott MW, Carter BS, Barker FG.Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload.J Neurosurg 2005 Jun;102(6):977-86.
    16028755
  • Barker FG, Curry WT, Carter BS.Surgery for primary supratentorial brain tumors in the United States, 1988 to 2000: the effect of provider caseload and centralization of care.Neuro-oncol 2005 Jan;7(1):49-63.
    15701282
  • Barker FG, Amin-Hanjani S.Changing neurosurgical workload in the United States, 1988-2001: craniotomy other than trauma in adults.Neurosurgery 2004 Sep;55(3):506-17; discussion 517-8.
    15335418
  • Barker FG, Carter BS, Ojemann RG, Jyung RW, Poe DS, McKenna MJ.Surgical excision of acoustic neuroma: patient outcome and provider caseload.Laryngoscope 2003 Aug;113(8):1332-43.
    12897555
  • Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA, Thornton AF, Loeffler JS, Henson JW, Gonzalez RG.In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience.Radiology 2002 Dec
    12461273
  • Chang SM, Barker FG, Schmidt MH, Sloan AE, Kasper R, Phillips L, Shih K, Hariharan S, Berger MS.Clinical trial participation among patients enrolled in the Glioma Outcomes Project.Cancer 2002 May 15;94(10):2681-7.
    12173337
  • Barker FG, Chang SM, Larson DA, Sneed PK, Wara WM, Wilson CB, Prados MD.Age and radiation response in glioblastoma multiforme.Neurosurgery 2001 Dec;49(6):1288-97; discussion 1297-.
    11846927
  • Barker FG, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS, Chen P, Israel MA, Aldape KD.EGFR overexpression and radiation response in glioblastoma multiforme.Int J Radiat Oncol Biol Phys 2001 Oct 1;51(2):410-8.
    11567815
  • Simmons ML, Lamborn KR, Takahashi M, Chen P, Israel MA, Berger MS, Godfrey T, Nigro J, Prados M, Chang S, Barker FG, Aldape K.Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients.Cance
    11221842
  • Barker FG, Chang SM, Gutin PH, Malec MK, McDermott MW, Prados MD, Wilson CB.Survival and functional status after resection of recurrent glioblastoma multiforme.Neurosurgery 1998 Apr;42(4):709-20; discussion 720-3.
    9574634
  • Barker FG, Davis RL, Chang SM, Prados MD.Necrosis as a prognostic factor in glioblastoma multiforme.Cancer 1996 Mar 15;77(6):1161-6.
    8635139
  • Barker FG, Prados MD, Chang SM, Davis RL, Gutin PH, Lamborn KR, Larson DA, McDermott MW, Sneed PK, Wilson CB.Bromodeoxyuridine labeling index in glioblastoma multiforme: relation to radiation response, age, and survival.Int J Radiat Oncol Biol Phys 1996 M
    8598356
  • Barker FG, Prados MD, Chang SM, Gutin PH, Lamborn KR, Larson DA, Malec MK, McDermott MW, Sneed PK, Wara WM, Wilson CB.Radiation response and survival time in patients with glioblastoma multiforme.J Neurosurg 1996 Mar;84(3):442-8.
    8609556