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Jonathan A. Fletcher, MD

Associate Professor, Department of Pathology, Harvard Medical School

Associate Professor, Department of Pediatrics, Harvard Medical School

Staff Medical and Pediatric Oncologist and Assocaite Pathologist, Pathology, Boston Children's Hospital

Clinical Associate, Pathology, Massachusetts General Hospital

Associate Pathologist, Pathology, Brigham And Women's Hospital

Contact Info

Jonathan Fletcher
Brigham And Women's Hospital
20 Shattuck Street

Boston, MA, 02115
Phone: 617-732-7883
Fax: 617-278-6921
jfletcher@partners.org

Assistant

Not Available.

DF/HCC Program Affiliation

Sarcoma
Gastrointestinal Malignancies
Cancer Genetics

Research Abstract

There are five areas of research focus in our laboratory. First is identification of novel therapeutic targets amongst the tyrosine kinase family of proteins. These efforts focus on sarcomas, mesothelioma, and other solid tumors. Second is discovery of oncogenic mechanisms and therapeutic targets in leiomyosarcoma, gastrointestinal stromal tumor, and mesothelioma. Third is use of molecular cytogenetic methods to identify novel oncogenes in solid tumors. Fourth is development of novel approaches to administering targeted therapies in cancer. Fifth is characterization of response and resistance mechanisms to targeted therapies in cancer.

Publications

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