DF/HCC Program Affiliation

Prostate Cancer, Leader

DF/HCC Associations

Member, Clinical Science Coordinating Committee
Principal Investigator, Prostate Cancer SPORE
Member, Center Scientific Council

Research Abstract

Our research team focuses on the molecular basis of genitourinary cancers and improved treatments for patients with prostate cancer, kidney cancer, bladder cancer, and testicular cancer. Laboratory research involves understanding the genetics of prostate cancer, while clinical research focuses on trials of novel therapeutics for genitourinary cancers.

In our laboratory, we have investigated germline, somatic genetic markers of prostate cancer behavior. We have identified germline markers of risk of prostate cancer, inherited variations that determine benefit from antioxidants, several mechanisms of resistance to androgen deprivation therapy including microRNAs and androgen transporters.
Our clinical trials have focused on:
- introducing novel therapeutics to patients with high-risk localized and metastatic prostate cancer including novel hormone therapies, chemotherapies and vaccines

Publications

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