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Edwin Choy, MD, PhD

Assistant Professor, Department of Medicine, Harvard Medical School

Director of Sarcoma Research, Hematology/Oncology, Massachusetts General Hospital

Contact Info

Edwin Choy
Massachusetts General Hospital
55 Fruit St
Boston, MA, 02114
Mailstop: Yawkey 7B
Phone: 617-724-4000
Fax: 617-643-1915


Donna Silva
55 Fruit Street
Massachusetts General Hospital
Boston, MA, 02114
Phone: 617-726-8748
Fax: 617-643-1915

DF/HCC Program Affiliation

Translational Pharmacology and Early Therapeutic Trials

Research Abstract

Sarcomas are rare malignant tumors derived from connective tissue. Although a substantial group of sarcomas are characterized by a defined chromosomal translocations, the molecular basis for most subtypes of sarcomas are unknown. In collaboration with investigators at MGH, DFCI, and The Broad Institute, we utilize high-throughput genotyping technology to understand the molecular basis of sarcomas in order to gain insight into novel therapeutic options for patients who otherwise have no treatment alternatives.
In addition to this translational approach, our clinical research team collaborates closely with the sarcoma team at DFCI in testing novel agents in our patient population in a phase I, II, or III setting. We are currently enrolling patients onto clinical trials perturbing the VEGF, PDGFR, PARP, IGF1R, mTor, src, DR5, VEGF, c-met, and hsp-90 pathways.


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