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Alan B Cantor, MD, PhD

Assistant Professor, Department of Pediatrics, Harvard Medical School

Assistant in Medicine, Medicine, Boston Children's Hospital

Contact Info

Alan Cantor
Children's Hospital Boston
300 Longwood Ave
Boston, MA, 02115
Mailstop: Karp 7
Phone: 617-919-2026
Fax: 617-730-0222
alan.cantor@childrens.harvard.edu

Assistant

Kathryn Entner
Medicine-Hematology
Boston Children's Hospital
300 Longwood Ave, Karp 7
Boston, MA, 02115
Mailstop: Karp 7
Phone: 617-919-2015
Fax: 617-730-0222
kathryn.entner@childrens.harvard.edu

DF/HCC Program Affiliation

Leukemia
Cancer Genetics

Lab Website

Cantor Lab Overview

Research Abstract

The Cantor laboratory is interested in further elucidating how dysregulation of normal hematopoietic transcriptional mechanisms contributes to human leukemogenesis. We have a particular interest in early initiating events events in leukemogenesis. This includes proteomic, genomic, epigenetic, and biochemical studies of members of the GATA and RUNX transcription factor families, which are frequently mutated in human leukemias. We have also applied genetic studies of familial leukemia/myelodysplastic predisposition syndromes, such as Familial Platelet Disorder with Propensity to Develop Leukemia (FPD/AML) to identify novel genes involved in human leukemogenesis. Our studies also examine the molecular basis of Down Syndrome Transient Myeloproliferative Disorder (DS-TMD) and Acute Megakaryoblastic Leukemia (DS-AMKL), as well as Juvenile Myelomonocytic Leukemia.

Publications

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