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Zhe Li

Assistant Professor, Department of Medicine, Harvard Medical School

Associate Geneticist, Medicine / Genetics, Brigham And Women's Hospital

Contact Info

Zhe Li
Brigham and Women's Hospital
77 Avenue Louis Pasteur
Boston, MA, 02115
Mailstop: NRB 458E
Phone: 617-525-4740
Fax: 617-525-4705
zli4@rics.bwh.harvard.edu

Assistant

Tracy Dunn
Administrative Assistant
Department of Medicine, Division of Genetics
Brigham And Women's Hospital
77 Avenue Louis Pasteur
Boston, MA, 02115
Mailstop: Harvard New Research Building
Phone: 617-525-4743
Fax: 617-525-4705
tdunn@partners.org

DF/HCC Program Affiliation

Prostate Cancer
Breast Cancer

Lab Website

BWH-Li Lab

Research Abstract

Research in my laboratory mainly focuses on developmental oncobiology of epithelial cancer. We are particularly interested in elucidating how cells of origin contribute to the cancer phenotype, and what is the molecular and cellular basis leading to formation of cancer stem cells (CSCs, also known as tumor-initiating cells, or tumor-propagating cells) from normal target cells of cancer. We study these by applying concepts and tools from stem cell biology and developmental biology, and by using a combination of mouse genetics, biochemistry, and genomic approaches. The long-term goal is to develop novel approaches to treat and/or to prevent cancer.

Publications

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