DF/HCC Program Affiliation

Translational Pharmacology and Early Therapeutic Trials
Cancer Survivorship

DF/HCC Associations

Scientific Advisor, Clinical Research Unit

Lab Website

http://www.cardio-onc.org

Research Abstract

The majority of my effort is devoted to basic investigation. My general interests include basic myocyte biology and myocardial adaptation to various stresses, including hypoxia, aging, and chemotherapies. Since joining the faculty at Brigham and Women's Hospital in July 2009, my clinical focus has been establishing "cardio-oncology" clinics at both the Dana-Farber Cancer Institute and Brigham and Women's Hospital providing care for cancer patients who develop cardiac complications during cancer treatment. Given my post-doctoral training at the Dana-Farber, I am particularly interested in treating cancer patients who receive novel molecular targeted therapies that may cause cardiovascular complications, including hypertension, hyperlipidemia, acute arterial and venous thromboembolic events, acute coronary syndrome, and cardiomyopathy. The observations from patients who develop cardiac complications from novel chemotherapies will provide testable hypotheses in the laboratory, which may provide better understanding of the mechanisms of cardiac disease and may, in time, translate into improvements in patient care.

Publications

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