Richard D. Gelber, PhD
Professor, Department of Pediatrics, Harvard Medical School
Professor, Department of Biostatistics, Harvard School Of Public Health
Professor, Biostatistics and Computational Biology, Dana-Farber Cancer Institute
Contact Info
Richard Gelber
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Mailstop: CLS11007
Phone: 617-632-3603
Fax: 617-632-2444
gelber@jimmy.harvard.edu
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Mailstop: CLS11007
Phone: 617-632-3603
Fax: 617-632-2444
gelber@jimmy.harvard.edu
Assistant
Not Available.DF/HCC Program Affiliation
Breast CancerBiostatistics and Computational Biology
Research Abstract
Dr. Gelber co-developed the Q-TWiST method (Quality-adjusted Time Without Symptoms of disease or Toxicity of treatment) for incorporating quality-of-life considerations into treatment comparisons. This quality-adjusted survival technique provides a framework to balance the benefits of disease control against theburdens of treatment side effects using threshold utility analysis and patient preferences. The method has been applied to treatment comparisons for patients with breast cancer, rectal cancer, HIV infection, brain tumors, childhood acute myeloid leukemia and melanoma.
Dr. Gelber's research includes interpretations of meta-analysis and evaluations of successful treatments for childhood cancers. In addition, he is responsible for the design, conduct, analysis and reporting of large scale randomized clinical trials evaluating treatments for breast cancer, pediatric malignancies and perinatal transmission of HIV.
