DF/HCC Program Affiliation

Breast Cancer
Biostatistics

DF/HCC Associations

Associate Director, Biostatistics

Research Abstract

My oncology research is related to breast cancer, biostatistics, and immunology. The breast cancer research includes studies of long-term toxicity (e.g. cardiac events after doxorubicin and/or radiation to left chest, MDS after alkylating agents), a recent grant submission on mathematical models of the effects of current and new breast cancer imaging methodology and therapy changes on national survival statistics, and studies of prognostic factors, most recently in DCIS patients. The immunology research includes studies of immunogenetics in mice and studies of patient and assay technique factors which influence the variability of tests such as lymphoproliferative assays, cytotoxic T lymphocyte assays, and immunophenotyping. The biostatistics research is related to breast cancer (e.g., competing risks methodology, analysis of non-proportional hazards, computing methods for SAGE analysis) or to immunology (e.g., interval censoring in animal studies, robust estimates of coefficient of variation in lab studies).

Publications

• Mitsuyasu R, Gelman R, Cherng DW, Landay A, Fahey J, Reichman R, Erice A, Bucy RP, Kilby JM, Lederman MM, Hamilton CD, Lertora J, White BL, Tebas P, Duliege AM, Pollard RB,.The virologic, immunologic, and clinical effects of interleukin 2 with potent anti
  17389292
• Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J, Nikolskaya T, Serebryiskaya T, Beroukhim R, Hu M, Halushka MK, Sukumar S, Parker LM, Anderson KS, Harris LN, Garber JE, Richardson AL, Schnitt SJ, Nikolsky Y, Gelman RS, Polyak
  17349583
• Carlson RW, Moench SJ, Hammond ME, Perez EA, Burstein HJ, Allred DC, Vogel CL, Goldstein LJ, Somlo G, Gradishar WJ, Hudis CA, Jahanzeb M, Stark A, Wolff AC, Press MF, Winer EP, Paik S, Ljung BM,.HER2 testing in breast cancer: NCCN Task Force report and re
  16813731
• Wüthrich C, Kesari S, Kim WK, Williams K, Gelman R, Elmeric D, De Girolami U, Joseph JT, Hedley-Whyte T, Koralnik IJ.Characterization of lymphocytic infiltrates in progressive multifocal leukoencephalopathy: co-localization of CD8(+) T cells with JCV-infe
  16798673
• Lim M, Bellon JR, Gelman R, Silver B, Recht A, Schnitt SJ, Harris JR.A prospective study of conservative surgery without radiation therapy in select patients with Stage I breast cancer.Int J Radiat Oncol Biol Phys 2006 Jul 15;65(4):1149-54.
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• Yao J, Weremowicz S, Feng B, Gentleman RC, Marks JR, Gelman R, Brennan C, Polyak K.Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression.Cancer Res 2006 Apr 15;66(8):4065-78.
  16618726
• Lin NU, Gelman R, Winer EP.Dose density in breast cancer: a simple message?.J Natl Cancer Inst 2005 Dec 7;97(23):1712-4.
  16333021
• Burstein HJ, Bellon JR, Galper S, Lu HM, Kuter I, Taghian AG, Wong J, Gelman R, Bunnell CA, Parker LM, Garber JE, Winer EP, Harris JR, Powell SN.Prospective evaluation of concurrent paclitaxel and radiation therapy after adjuvant doxorubicin and cyclophos
  16243442
• Gelman R, Harris JR.Editorial comment on "the link between local recurrence and distant metastasis in human breast cancer" by Serge Koscielny and Maurice Tubiana.Int J Radiat Oncol Biol Phys 1999 Jan 1;43(1):7-9.
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• Shapiro CL, Hardenbergh PH, Gelman R, Blanks D, Hauptman P, Recht A, Hayes DF, Harris J, Henderson IC.Cardiac effects of adjuvant doxorubicin and radiation therapy in breast cancer patients.J Clin Oncol 1998 Nov;16(11):3493-501.
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