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Gian-Paolo Dotto, MD, PhD

Biologist, Cutaneous Biology Research Center, Massachusetts General Hospital

Contact Info

Gian-Paolo Dotto
Massachusetts General Hospital
Building 149

Charlestown, MA, 02129
Phone: 617-724-9538
Fax: 617-726-4453
gdotto@partners.org

Assistant

Bonnie Carroll
Administrative Assistant
Cutaneous Biology Research Center
Massachusetts General Hospital
Building 149
13th Street
Charlestown, MA, 02129
Phone: 617-726-7130
Fax: 617-726-2120
bcarroll2@partners.org

DF/HCC Program Affiliation

Cutaneous Oncology and Melanoma

Research Abstract

Our main research contributions have been in the fields of multistep carcinogenesis, and in signal transduction, cell cycle control mechanisms underlying the switch between keratinocyte growth differentiation. In particular, over the last few years my laboratory has played a significant role in two major areas : 1) Tyrosine and phosphorylation in keratinocyte differentiation control and 2) The role of the cyclin dependent kinase inhibitor p21Cip1/WAF1 in growth/differentiation control and tumorigenesis.

Publications

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