Research Abstract

Our laboratory research foucuses on evaluating the potential estrogenioity of commonly used herbal remedies. These studies are performed in estrogen sensitive and estrogen insensitive breast cancer cell lines. These studies include investigations on estrogen regulated gene induction, cell cycle analysis, growth proliferation studies and mechanism of action.

Publications

• Duda RB, Zhong Y, Navas V, Li MZ, Toy BR, Alavarez JG.American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth.J Surg Oncol 1999 Dec;72(4):230-9.
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• Duda RB, Taback B, Kessel B, Dooley DD, Yang H, Marchiori J, Slomovic BM, Alvarez JG.pS2 expression induced by American ginseng in MCF-7 breast cancer cells.Ann Surg Oncol 1996 Nov;3(6):515-20.
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