DF/HCC Program Affiliation

Lung Cancer
Cancer Imaging

Research Abstract

Most of my work is in the field of image-guided adaptive radiotherapy. The main focus of my research is developing techniques for overcoming respiratory motion in the irradiation of abdominal and thoracic cancer patients. Respiratory motion significantly limits our ability to deliver a lethal dose to unattached tumors in the abdomen and thorax. We are currently investigating fluoroscopic tumor tracking with or without implanted fiducials and treatment beam gating either based on the internal signal or an external surrogate. We are also studying the use of the treatment beam, itself, for tumor position verification and adaptive treatment. Addition projects include in molecular biophysics and imaging for radiotherapy applications.

Publications

• Berbeco RI, Hacker F, Zatwarnicki C, Park SJ, Ionascu D, O'Farrell D, Mamon HJ.A novel method for estimating SBRT delivered dose with beam's-eye-view images.Med Phys 2008 Jul;35(7):3225-31.
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• Park SJ, Ionascu D, Killoran J, Mamede M, Gerbaudo VH, Chin L, Berbeco R.Evaluation of the combined effects of target size, respiratory motion and background activity on 3D and 4D PET/CT images.Phys Med Biol 2008 Jul 7;53(13):3661-79.
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• Berbeco RI, Mostafavi H, Sharp GC, Jiang SB.Towards fluoroscopic respiratory gating for lung tumours without radiopaque markers.Phys Med Biol 2005 Oct 7;50(19):4481-90.
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