DF/HCC Program Affiliation

Cancer Imaging

Research Abstract

Our research focuses on the use of magnetic resonance imaging (MRI) in the detection and staging of breast cancer and, too, the use of MRI in assessing response of breast cancer to therapy. We are pursuing techniques for improving the accuracy of MRI in breast cancer detection, including the use of combined high spatial and high temporal resolution imaging. With the anticipated installation of a high field 3 Testa-magnet in December 1999, we look forward to investigating the use of MR spectroscopy for improving the specificity of breast cancer diagnosis with MRI. At present, we are involved in two NCI-sponsored multi-institutional studies, one assessing the accuracy of MRI for detection and staging of breast cancer in women presenting with suspicious palpable and/or mammographic breast lesions and the other a pilot study aimed at evaluating the potential of MRI for detecting interval cancers in a population of women who are at high risk for developing breast cancer.

Publications

• Hochman MG, Orel SG, Powell CM, Schnall MD, Reynolds CA, White LN.Fibroadenomas: MR imaging appearances with radiologic-histopathologic correlation.Radiology 1997 Jul;204(1):123-9.
  9205233
• Nunes LW, Schnall MD, Orel SG, Hochman MG, Langlotz CP, Reynolds CA, Torosian MH.Breast MR imaging: interpretation model.Radiology 1997 Mar;202(3):833-41.
  9051042
• Orel SG, Hochman MG, Schnall MD, Reynolds C, Sullivan DC.High-resolution MR imaging of the breast: clinical context.Radiographics 1996 Nov;16(6):1385-401.
  8946543