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John W. Chen, MD, PhD

Assistant Professor, Department of Radiology, Harvard Medical School

Assistant Radiologist, Radiology, Massachusetts General Hospital

Contact Info

John Chen
Massachusetts General Hospital
Rm 8222 Simches Research Building
Boston, MA, 02114
Phone: 617-726-8320
chenjo@helix.mgh.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Cancer Imaging
Neuro-Oncology

Research Abstract

My primary research focus is on the molecular imaging of neurological diseases. We have developed the first small-chelate MR agent targeting myeloperoxidase, an enzyme secreted by neutrophils and macrophages in cancers and other inflammatory diseases. By imaging the inflammatory response surrounding tumors, we may be able to increase our diagnostic sensitivity in detection and in evaluating treatment response. In addition to small-chelate agents, we also employ novel iron-oxide nanoparticle MR agents and optical methods to improve the imaging of oncological diseases.

Publications

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