DF/HCC Program Affiliation

Sarcoma

Research Abstract

Research focuses on the diagnosis and amelioration of late cardiac effects in cancer survivors and understanding treatment-related cardiac effects in patients currently undergoing cancer treatment. Ongoing studies include: 1) the use of noninvasive imaging to detect and manage radiation-induced heart disease in long-term Hodgkin’s Disease survivors and 2) the cardiac effects of new experimental cancer therapies such as SU11248. Previous research, supported by the American Heart Association, explored ways of modifying radiation therapy delivery to decrease cardiotoxicity during breast cancer treatment. Additional interests include assessing disease prevalence amongst diverse populations.

Publications

• Chen MH, Cash EP, Danias PG, Kissinger KV, Bornstein BA, Rhodes LM, Gelman R, Harris JR, Manning WJ.Respiratory maneuvers decrease irradiated cardiac volume in patients with left-sided breast cancer.J Cardiovasc Magn Reson 2002;4(2):265-71.
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• Chen MH, Danias P, Cash E, Cameron E, Salton C, Kissinger K, Gelman R, Harris JR, Mauch P, Manning WJ.Left ventricular systolic dysfunction and impaired aortic compliance in moderate-term survivors of Hodgkin's mantle radiation: a CMR study.Eval & Pro
• Chen MH, Chuang ML, Bornstein BA, Gelman R, Harris JR, Manning WJ.Impact of respiratory maneuvers on cardiac volume within left-breast radiation portals.Circulation 1997 Nov 18;96(10):3269-72.
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