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Monica M. Bertagnolli, MD

Professor, Department of Surgery, Harvard Medical School

Associate Surgeon, Surgery, Brigham And Women's Hospital

Contact Info

Monica Bertagnolli
Brigham And Women's Hospital
75 Francis Street
Boston, MA, 02115
Mailstop: Rm# CA-104
Phone: 617-732-8910
Fax: 617-582-6177
Email not available

Assistant

Michelle Lapidus Ouelette
Surgery
Brigham And Women's Hospital
Phone: 617-632-3000
michelle_lapidus@dfci.harvard.edu

DF/HCC Program Affiliation

Gastrointestinal Malignancies
Sarcoma

DF/HCC Associations

Member, Clinical Science Coordinating Committee

Research Abstract

Dr. Bertagnolli’s laboratory studies the APC (Adenomatous Polyposis Coli) gene, an important factor in colorectal carcinogenesis and in the development of desmoid tumors. Using animal tumor models of the human disease, Familial Adenomatous Polyposis, the laboratory investigates the mechanisms of tumor transformation initiated by APC mutation or loss. The laboratory also studies modulation of APC gene activity and tumor formation by chemopreventive drugs. This work includes animal model studies, and also human clinical trials in colorectal adenoma prevention and risk assessment.

Publications

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