John M. Asara, Ph.D.

Director, Mass Spectrometry Core, Beth Israel Deaconess Medical Center

Contact Info

John Asara
Beth Israel Deaconess Medical Center
3 Blackfan Circle

Boston, MA, 02115
Mailstop: CLS 409
Phone: 617-735-2651
Fax: 617-735-2646
jasara@bidmc.harvard.edu

Assistant

Not Available.

DF/HCC Program Affiliation

Lab Website

Research Abstract

Publications

• Dibble CC, Asara JM, Manning BD.Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.Mol Cell Biol 2009 Nov;29(21):5657-70.
  19720745
• Schweitzer MH,Zheng W,Organ CL,Avci R,Suo Z,Freimark LM,Lebleu VS,Duncan MB,Vander Heiden MG,Neveu JM,Lane WS,Cottrell JS,Horner JR,Cantley LC,Kalluri R,Asara JM.Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis.
  19407199
• Zheng B,Jeong JH,Asara JM,Yuan YY,Granter SR,Chin L,Cantley LC.Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation.Mol Cell 2009 Jan 30;33(2):237-47.
  19187764
• Organ CL,Schweitzer MH,Zheng W,Freimark LM,Cantley LC,Asara JM.Molecular phylogenetics of mastodon and Tyrannosaurus rex.Science 2008 Apr 25;320(5875):499.
  18436782
• Christofk HR, Vander Heiden MG, Wu N, Asara JM, Cantley LC.Pyruvate kinase M2 is a phosphotyrosine-binding protein.Nature 2008 Mar 13;452(7184):181-6.
  18337815
• Asara JM, Christofk HR, Freimark LM, Cantley LC.A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen.Proteomics 2008 Mar;8(5):994-9.
  18324724
• Asara JM, Schweitzer MH, Freimark LM, Phillips M, Cantley LC.Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry.Science 2007 Apr 13;316(5822):280-285.
  17431180
• Asara JM, Zhang X, Zheng B, Maroney LA, Christofk HR, Wu N, Cantley LC.In-gel stable isotope labeling for relative quantification using mass spectrometry.Nat Protoc 2006;1(1):46-51.
  17406210
• Kane S, Sano H, Liu SC, Asara JM, Lane WS, Garner CC, Lienhard GE.A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain.J Biol Chem 2002 Jun 21;277(25):22115-8.
  11994271
• Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG.HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.Science 2001 Apr 20;292(5516):464-8.
  11292862