• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

David C. Christiani, MD, MPH

Publications

  • Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, Chatterjee N, Thorleifsson G, Sulem P, Liu G, Kaaks R, Henrion M, Kinnersley B, Vallée M, LeCalvez-Kelm F, Stevens VL, Gapstur SM, Chen WV, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njølstad I, Chen C, Goodman G, Benhamou S, Vooder T, Välk K, Nelis M, Metspalu A, Lener M, Lubiński J, Johansson M, Vineis P, Agudo A, Clavel-Chapelon F, Bueno-de-Mesquita HB, Trichopoulos D, Khaw KT, Johansson M, Weiderpass E, Tjønneland A, Riboli E, Lathrop M, Scelo G, Albanes D, Caporaso NE, Ye Y, Gu J, Wu X, Spitz MR, Dienemann H, Rosenberger A, Su L, Matakidou A, Eisen T, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Landi MT, Houlston RS, Amos CI.Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.Nat Genet. 2014 Jun 1.
    24880342
  • Wang X, Lin S, Yano E, Yu IT, Courtice M, Lan Y, Christiani DC.Exposure-specific lung cancer risks in Chinese chrysotile textile workers and mining workers.Lung Cancer. 2014 May 9.
    24854404
  • Kinsey CM, Estepar RS, Zhao Y, Yu X, Diao N, Heist RS, Wain JC, Mark EJ, Washko G, Christiani DC.Invasive adenocarcinoma of the lung is associated with the upper lung regions.Lung Cancer. 2014 May;84(2):145-50.
    24598367
  • Pu X, Hildebrandt MA, Lu C, Roth JA, Stewart DJ, Zhao Y, Heist RS, Ye Y, Chang DW, Su L, Minna JD, Lippman SM, Spitz MR, Christiani DC, Wu X.Inflammation-related Genetic Variations and Survival for Advanced Non-Small Cell Lung Cancer Receiving First-line Chemotherapy.Clin Pharmacol Ther. 2014 Apr 22.
    24755914
  • Seow WJ, Kile ML, Baccarelli AA, Pan WC, Byun HM, Mostofa G, Quamruzzaman Q, Rahman M, Lin X, Christiani DC.Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: A case-control follow-up study.Environ Mol Mutagen. 2014 Feb 23.
    24677489
  • Lin S, Wang X, Yano E, Yu I, Lan Y, Courtice MN, Christiani DC.Exposure to chrysotile mining dust and digestive cancer mortality in a Chinese miner/miller cohort.Occup Environ Med. 2014 May;71(5):323-8.
    24436059
  • Park SL, Fesinmeyer MD, Timofeeva M, Caberto CP, Kocarnik JM, Han Y, Love SA, Young A, Dumitrescu L, Lin Y, Goodloe R, Wilkens LR, Hindorff L, Fowke JH, Carty C, Buyske S, Schumacher FR, Butler A, Dilks H, Deelman E, Cote ML, Chen W, Pande M, Christiani DC, Field JK, Bickebller H, Risch A, Heinrich J, Brennan P, Wang Y, Eisen T, Houlston RS, Thun M, Albanes D, Caporaso N, Peters U, North KE, Heiss G, Crawford DC, Bush WS, Haiman CA, Landi MT, Hung RJ, Kooperberg C, Amos CI, Le Marchand L, Cheng I.Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia.Journal of the National Cancer Institute. 2014 Apr 1;106(4):dju061.
    24681604
  • Borger DR, Goyal L, Yau T, Poon RT, Ancukiewicz M, Deshpande V, Christiani DC, Liebman HM, Yang H, Kim H, Yen K, Faris JE, Iafrate AJ, Kwak EL, Clark JW, Allen JN, Blaszkowsky LS, Murphy JE, Saha SK, Hong TS, Wo JY, Ferrone CR, Tanabe KK, Bardeesy N, Straley KS, Agresta S, Schenkein DP, Ellisen LW, Ryan DP, Zhu AX.Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma.Clin Cancer Res. 2014 Apr 1;20(7):1884-90.
    24478380
  • Kim CH, Lee YC, Hung RJ, McNallan SR, Cote ML, Lim WY, Chang SC, Kim JH, Ugolini D, Chen Y, Liloglou T, Andrew AS, Onega T, Duell EJ, Field JK, Lazarus P, Marchand LL, Neri M, Vineis P, Kiyohara C, Hong YC, Morgenstern H, Matsuo K, Tajima K, Christiani DC, McLaughlin JR, Bencko V, Holcatova I, Boffetta P, Brennan P, Fabianova E, Foretova L, Janout V, Lissowska J, Mates D, Rudnai P, Szeszenia-Dabrowska N, Mukeria A, Zaridze D, Seow A, Schwartz AG, Yang P, Zhang ZF.Exposure to secondhand tobacco smoke and lung cancer by histological type: A pooled analysis of the International Lung Cancer Consortium (ILCCO).Int J Cancer. 2014 Mar 11.
    24615328
  • Wong JY, De Vivo I, Lin X, Grashow R, Cavallari J, Christiani DC.The association between global DNA methylation and telomere length in a longitudinal study of boilermakers.Genet Epidemiol. 2014 Apr;38(3):254-64.
    24616077
  • Wong JY, De Vivo I, Lin X, Christiani DC.Cumulative PM(2.5) exposure and telomere length in workers exposed to welding fumes.J. Toxicol. Environ. Health Part A. 2014;77(8):441-55.
    24627998
  • Christiani DC.Radiation risk from lung cancer screening: glowing in the dark?.Chest. 2014 Mar 1;145(3):439-40.
    24590012
  • Liu L, Zhong R, Zou L, Fu J, Zhu B, Chen W, Ye X, Gao Y, Yang Y, Christiani DC, Chen S, Miao X.Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers.Cancer Epidemiology. 2014 Feb;38(1):66-72.
    24456789
  • Kile ML, Houseman EA, Baccarelli A, Quamruzzaman Q, Rahman M, Mostofa G, Cardenas A, Wright RO, Christiani DC.Effect of prenatal arsenic exposure on DNA methylation and leukocyte subpopulations in cord blood.Epigenetics. 2014 Feb 13;9(5).
    24525453
  • Zhai R, Yu X, Shafer A, Wain JC, Christiani DC.The impact of coexisting COPD on survival of patients with early-stage non-small cell lung cancer undergoing surgical resection.Chest. 2014 Feb;145(2):346-53.
    24008835
  • Wong JY, De Vivo I, Lin X, Fang SC, Christiani DC.The relationship between inflammatory biomarkers and telomere length in an occupational prospective cohort study.PLoS ONE. 2014;9(1):e87348.
    24475279
  • Liao SY, Lin X, Christiani DC.Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study.Environ Health. 2013;12:101.
    24289273
  • Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM.Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation.PLoS Med. 2013 Dec;10(12):e1001577; discussion e1001577.
    24391478
  • Zhai R, Yu X, Wei Y, Su L, Christiani DC.Smoking and smoking cessation in relation to the development of co-existing non-small cell lung cancer with chronic obstructive pulmonary disease.Int J Cancer. 2014 Feb 15;134(4):961-70.
    23921845
  • North CM, Christiani DC.Women and lung cancer: what is new?.Semin Thorac Cardiovasc Surg. 2013;25(2):87-94.
    24216523
  • Vamvini MT, Aronis KN, Panagiotou G, Huh JY, Chamberland JP, Brinkoetter MT, Petrou M, Christophi CA, Kales SN, Christiani DC, Mantzoros CS.Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans.European Journal Of Endocrinology / European Federation Of Endocrine Societies. 2013;169(6):829-34.
    24062354
  • Applebaum KM, Ray RM, Astrakianakis G, Gao DL, Thomas DB, Christiani DC, LaValley MP, Li W, Checkoway H, Eisen EA.Evidence of a paradoxical relationship between endotoxin and lung cancer after accounting for left truncation in a study of Chinese female textile workers.Occup Environ Med. 2013 Oct;70(10):709-15.
    23759537
  • Qian ZR, Ter-Minassian M, Chan JA, Imamura Y, Hooshmand SM, Kuchiba A, Morikawa T, Brais LK, Daskalova A, Heafield R, Lin X, Christiani DC, Fuchs CS, Ogino S, Kulke MH.Prognostic significance of MTOR pathway component expression in neuroendocrine tumors.J Clin Oncol. 2013 Sep 20;31(27):3418-25.
    23980085
  • Renouf DJ, Zhai R, Sun B, Xu W, Cheung WY, Heist RS, Kulke MH, Cescon D, Asomaning K, Marshall AL, Li S, Christiani DC, Liu G.Association of MDM2 T309G and p53 Arg72Pro polymorphisms and gastroesophageal reflux disease with survival in esophageal adenocarcinoma.J Gastroenterol Hepatol. 2013 Sep;28(9):1482-8.
    23735059
  • Wang X, Yano E, Lin S, Yu IT, Lan Y, Tse LA, Qiu H, Christiani DC.Cancer mortality in Chinese chrysotile asbestos miners: exposure-response relationships.PLoS ONE. 2013;8(8):e71899.
    23991003
  • Kirkeleit J, Riise T, Bjørge T, Christiani DC.The Healthy Worker Effect in Cancer Incidence Studies.Am J Epidemiol. 2013 Apr 17.
    23595008
  • Calvo JA, Moroski-Erkul CA, Lake A, Eichinger LW, Shah D, Jhun I, Limsirichai P, Bronson RT, Christiani DC, Meira LB, Samson LD.Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by parp1.PLoS Genet. 2013 Apr;9(4):e1003413.
    23593019
  • Ter-Minassian M, Chan JA, Hooshmand SM, Brais LK, Daskalova A, Heafield R, Buchanan L, Qian ZR, Fuchs CS, Lin X, Christiani DC, Kulke MH.Clinical presentation, recurrence, and survival in patients with neuroendocrine tumors: results from a prospective institutional database.Endocr. Relat. Cancer. 2013;20(2):187-96.
    23319495
  • Soto GJ, Frank AJ, Christiani DC, Gong MN.The authors reply.Crit Care Med. 2013 Jan;41(1):e13.
    23269166
  • Heist RS, Mino-Kenudson M, Sequist LV, Tammireddy S, Morrissey L, Christiani DC, Engelman JA, Iafrate AJ.FGFR1 amplification in squamous cell carcinoma of the lung.J Thorac Oncol. 2012 Dec;7(12):1775-80.
    23154548
  • Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL.Informed conditioning on clinical covariates increases power in case-control association studies.PLoS Genet. 2012 Nov;8(11):e1003032.
    23144628
  • Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeböller H, Risch A, McKay JD, Wang Y, Dai J, Gaborieau V, McLaughlin J, Brenner D, Narod SA, Caporaso NE, Albanes D, Thun M, Eisen T, Wichmann HE, Rosenberger A, Han Y, Chen W, Zhu D, Spitz M, Wu X, Pande M, Zhao Y, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njølstad I, Chen C, Goodman G, Lathrop M, Benhamou S, Vooder T, Välk K, Nelis M, Metspalu A, Raji O, Chen Y, Gosney J, Liloglou T, Muley T, Dienemann H, Thorleifsson G, Shen H, Stefansson K, Brennan P, Amos CI, Houlston R, Landi MT, .Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.Hum Mol Genet. 2012 Nov 15;21(22):4980-95.
    22899653
  • Zhao Y, Chen F, Zhai R, Lin X, Diao N, Christiani DC.Association Test Based on SNP Set: Logistic Kernel Machine Based Test vs. Principal Component Analysis.PLoS ONE. 2012;7(9):e44978.
    23028716
  • Hu L, Wu C, Zhao X, Heist R, Su L, Zhao Y, Han B, Cao S, Chu M, Dai J, Dong J, Shu Y, Xu L, Chen Y, Wang Y, Lu F, Jiang Y, Yu D, Chen H, Tan W, Ma H, Chen J, Jin G, Wu T, Lu D, Christiani DC, Lin D, Hu Z, Shen H.Genome-Wide Association Study of Prognosis in Advanced Non-Small Cell Lung Cancer Patients Receiving Platinum-Based Chemotherapy.Clin Cancer Res. 2012 Oct 1;18(19):5507-5514.
    22872573
  • Raji OY, Duffy SW, Agbaje OF, Baker SG, Christiani DC, Cassidy A, Field JK.Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer: a case-control and cohort validation study.Ann Intern Med. 2012 Aug 21;157(4):242-50.
    22910935
  • Lee S, Emond MJ, Bamshad MJ, Barnes KC, Rieder MJ, Nickerson DA, , Christiani DC, Wurfel MM, Lin X.Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies.Am J Hum Genet. 2012 Aug 10;91(2):224-37.
    22863193
  • Spitz MR, Gorlov IP, Dong Q, Wu X, Chen W, Chang DW, Etzel CJ, Caporaso NE, Zhao Y, Christiani DC, Brennan P, Albanes D, Shi J, Thun M, Landi MT, Amos CI.Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers.Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1213-21.
    22573796
  • Kile ML, Hoffman E, Rodrigues EG, Breton CV, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh YM, Christiani DC.A Pathway-based Analysis of Urinary Arsenic Metabolites and Skin Lesions.Am J Epidemiol. 2011 Apr 1;173(7):778-86.
    21378128
  • Wu IC, Zhao Y, Zhai R, Liu CY, Chen F, Ter-Minassian M, Asomaning K, Su L, Heist RS, Kulke MH, Liu G, Christiani DC.Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.Carcinogenesis. 2011 Apr;32(4):502-6.
    21212151
  • Christiani DC.Combating environmental causes of cancer.N Engl J Med. 2011 Mar 3;364(9):791-3.
    21366471
  • Christiani DC.ERCC2/XPD polymorphisms and lung cancer risk.J Thorac Oncol. 2011 Jan;6(1):233; author reply 233-5.
    21178723
  • Boffetta P, Jayaprakash V, Yang P, Asomaning K, Muscat JE, Schwartz AG, Zhang ZF, Le Marchand L, Cote ML, Stoddard SM, Morgenstern H, Hung RJ, Christiani DC.Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO).Cancer Causes Control. 2011 Jan;22(1):73-9.
    21072579
  • Costello S, Friesen MC, Christiani DC, Eisen EA.Metalworking Fluids and Malignant Melanoma in Autoworkers.Epidemiology. 2011 Jan;22(1):90-7.
    20975563
  • Lee MS, Su L, Mark EJ, Wain JC, Christiani DC.Genetic Modifiers of Carcinogen DNA Adducts in Target Lung and Peripheral Blood Mononuclear Cells.Carcinogenesis. 2010 Dec;31(12):2091-6.
    20935060
  • Yin M, Yan J, Voutsina A, Tibaldi C, Christiani DC, Heist RS, Rosell R, Booton R, Wei Q.No evidence of an association of ERCC1 and ERCC2 polymorphisms with clinical outcomes of platinum-based chemotherapies in non-small cell lung cancer: A meta-analysis.Lung Cancer. 2010 Nov 12.
    21075476
  • Mehta AJ, Malloy EJ, Applebaum KM, Schwartz J, Christiani DC, Eisen EA.Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry.Scand J Work Environ Health. 2010 Nov;36(6):499-508.
    20835688
  • Paulus JK, Zhou W, Kraft P, Johnson BE, Lin X, Christiani DC.Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women.Lung Cancer. 2010 Jul 22.
    20655613
  • Liu CY, Wu MC, Chen F, Ter-Minassian M, Asomaning K, Zhai R, Wang Z, Su L, Heist RS, Kulke MH, Lin X, Liu G, Christiani DC.A Large Scale Genetic Association Study of Esophageal Adenocarcinoma Risk.Carcinogenesis. 2010 Jul;31(7):1259-63.
    20453000
  • Abejie BA, Wang X, Kales SN, Christiani DC.Patterns of pulmonary dysfunction in asbestos workers: a cross-sectional study.J Occup Med Toxicol. 2010;5:12.
    20525229
  • Lee MS, Su L, Christiani DC.Synergistic effects of NAT2 slow and GSTM1 null genotypes on carcinogen DNA damage in the lung.Cancer Epidemiol Biomarkers Prev. 2010 Jun;19(6):1492-7.
    20501762
  • Kirkeleit J, Riise T, Bjørge T, Moen BE, Bråtveit M, Christiani DC.Increased risk of oesophageal adenocarcinoma among upstream petroleum workers.Occup Environ Med. 2010 May;67(5):335-40.
    19858535
  • Zhai R, Chen F, Liu G, Su L, Kulke MH, Asomaning K, Lin X, Heist RS, Nishioka NS, Sheu CC, Wain JC, Christiani DC.Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma.J Clin Oncol. 2010 May 10;28(14):2445-51.
    20385987
  • Christiani DC.The environment and the lung: detection, prevention, and mechanism of disease.Proc Am Thorac Soc. 2010 May;7(2):146-8.
    20427589
  • Chen YC, Christiani DC, Su HJ, Hsueh YM, Smith TJ, Ryan LM, Chao SC, Lee JY, Guo YL.Early-life or lifetime sun exposure, sun reaction, and the risk of squamous cell carcinoma in an Asian population.Cancer Causes Control. 2010 May;21(5):771-6.
    20084542
  • Sun Q, Cornelis MC, Kraft P, Qi L, van Dam RM, Girman CJ, Laurie CC, Mirel DB, Gong H, Sheu CC, Christiani DC, Hunter DJ, Mantzoros CS, Hu FB.Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels.Hum Mol Genet. 2010 May 1;19(9):1846-55.
    20167575
  • Li Y, Sheu CC, Ye Y, de Andrade M, Wang L, Chang SC, Aubry MC, Aakre JA, Allen MS, Chen F, Cunningham JM, Deschamps C, Jiang R, Lin J, Marks RS, Pankratz VS, Su L, Li Y, Sun Z, Tang H, Vasmatzis G, Harris CC, Spitz MR, Jen J, Wang R, Zhang ZF, Christiani DC, Wu X, Yang P.Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.Lancet Oncol. 2010 Apr;11(4):321-30.
    20304703
  • Ji F, Wang W, Xia ZL, Zheng YJ, Qiu YL, Wu F, Miao WB, Jin RF, Qian J, Jin L, Zhu YL, Christiani DC.Prevalence and Persistence of Chromosomal Damage, and Susceptible Genotypes of Metabolic and DNA Repair Genes in Chinese Vinyl Chloride-exposed Workers.Carcinogenesis. 2010 Apr;31(4):648-53.
    20100738
  • Wu CF, Feng NH, Chong IW, Wu KY, Lee CH, Hwang JJ, Huang CT, Lee CY, Chou ST, Christiani DC, Wu MT.Second-hand smoke and chronic bronchitis in Taiwanese women: a health-care based study.BMC Public Health. 2010;10:44.
    20109222
  • Paulus JK, Asomaning K, Kraft P, Johnson BE, Lin X, Christiani DC.Parity and risk of lung cancer in women.Am J Epidemiol. 2010 Mar 1;171(5):557-63.
    20123687
  • Li YJ, Tsai YC, Chen YC, Christiani DC.Human papilloma virus and female lung adenocarcinoma.Semin Oncol. 2009 Dec;36(6):542-52. Review.
    19995646
  • Tejera P,Wang Z,Zhai R,Su L,Sheu CC,Taylor DM,Chen F,Gong MN,Thompson BT,Christiani DC.Genetic Polymorphisms of Peptidase Inhibitor 3 (Elafin) are Associated with ARDS.Am J Respir Cell Mol Biol. 2009 Dec;41(6):696-704.
    19251943
  • Sholl LM, Yeap BY, Iafrate AJ, Holmes-Tisch AJ, Chou YP, Wu MT, Goan YG, Su L, Benedettini E, Yu J, Loda M, Jänne PA, Christiani DC, Chirieac LR.Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.Cancer Res. 2009 Nov 1;69(21):8341-8.
    19826035
  • Sholl LM, Yeap BY, Iafrate AJ, Holmes-Tisch AJ, Chou YP, Wu MT, Goan YG, Su L, Benedettini E, Yu J, Loda M, Jänne PA, Christiani DC, Chirieac LR.Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.Cancer Res. 2009 Nov 1;69(21):8341-8348.
  • Kim JY, Prouty LA, Fang SC, Rodrigues EG, Magari SR, Modest GA, Christiani DC.Association between fine particulate matter and oxidative DNA damage may be modified in individuals with hypertension.J Occup Environ Med. 2009 Oct;51(10):1158-66.
    19786898
  • Cheung WY, Zhai R, Kulke MH, Heist RS, Asomaning K, Ma C, Wang Z, Su L, Lanuti M, Tanabe KK, Christiani DC, Liu G.Epidermal growth factor A61G gene polymorphism, gastroesophageal reflux disease and esophageal adenocarcinoma risk.Carcinogenesis. 2009 Aug;30(8):1363-7.
    19520791
  • Bradbury PA, Kulke MH, Heist RS, Zhou W, Ma C, Xu W, Marshall AL, Zhai R, Hooshmand SM, Asomaning K, Su L, Shepherd FA, Lynch TJ, Wain JC, Christiani DC, Liu G.Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes.Pharmacogenet Genomics. 2009 Aug;19(8):613-25.
    19620936
  • Sheu CC, Zhai R, Wang Z, Gong MN, Tejera P, Chen F, Su L, Thompson BT, Christiani DC.Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome.Intensive Care Med. 2009 Aug;35(8):1343-51.
    19526221
  • Bradbury PA, Zhai R, Ma C, Xu W, Hopkins J, Kulke MJ, Asomaning K, Wang Z, Su L, Heist RS, Lynch TJ, Wain JC, Christiani D, Liu G.Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.Clin Cancer Res. 2009 Jul 15;15(14):4680-5.
    19584152
  • Huang YT,Heist RS,Chirieac LR,Lin X,Skaug V,Zienolddiny S,Haugen A,Wu MC,Wang Z,Su L,Asomaning K,Christiani DC.Genome-wide analysis of survival in early-stage non-small-cell lung cancer.J Clin Oncol. 2009 Jun 1;27(16):2660-7.
    19414679
  • Cescon DW,Bradbury PA,Asomaning K,Hopkins J,Zhai R,Zhou W,Wang Z,Kulke M,Su L,Ma C,Xu W,Marshall AL,Heist RS,Wain JC,Lynch TJ Jr,Christiani DC,Liu G.p53 Arg72Pro and MDM2 T309G polymorphisms, histology, and esophageal cancer prognosis.Clin Cancer Res. 2009 May 1;15(9):3103-9.
    19383811
  • Christiani DC.Lung cancer genetics: a family affair?.Clin Cancer Res. 2009 Apr 15;15(8):2581-2.
    19351746
  • Bradbury PA,Zhai R,Hopkins J,Kulke MH,Heist RS,Singh S,Zhou W,Ma C,Xu W,Asomaning K,Ter-Minassian M,Wang Z,Su L,Christiani DC,Liu G.Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.Carcinogenesis. 2009 May;30(5):793-8.
    19321798
  • Temel JS,Greer JA,Goldberg S,Vogel PD,Sullivan M,Pirl WF,Lynch TJ,Christiani DC,Smith MR.A structured exercise program for patients with advanced non-small cell lung cancer.J Thorac Oncol. 2009 May;4(5):595-601.
    19276834
  • Wu MC,Zhang L,Wang Z,Christiani DC,Lin X.Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection.Bioinformatics. 2009 May 1;25(9):1145-51.
    19168911
  • Liu CY,Hsu YH,Wu MT,Pan PC,Ho CK,Su L,Xu X,Li Y,Christiani DC.Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study.BMC Cancer. 2009;9:15.
    19144145
  • Lee PS,Patel SR,Christiani DC,Bajwa E,Stossel TP,Waxman AB.Plasma gelsolin depletion and circulating actin in sepsis: a pilot study.PLoS ONE. 2008;3(11):e3712.
    19002257
  • Hung RJ,Christiani DC,Risch A,Popanda O,Haugen A,Zienolddiny S,Benhamou S,Bouchardy C,Lan Q,Spitz MR,Wichmann HE,LeMarchand L,Vineis P,Matullo G,Kiyohara C,Zhang ZF,Pezeshki B,Harris C,Mechanic L,Seow A,Ng DP,Szeszenia-Dabrowska N,Zaridze D,Lissowska J,Rudnai P,Fabianova E,Mates D,Foretova L,Janout V,Bencko V,Caporaso N,Chen C,Duell EJ,Goodman G,Field JK,Houlston RS,Hong YC,Landi MT,Lazarus P,Muscat J,McLaughlin J,Schwartz AG,Shen H,Stucker I,Tajima K,Matsuo K,Thun M,Yang P,Wiencke J,Andrew AS,Monnier S,Boffetta P,Brennan P.International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3081-9.
    18990748
  • Heist RS,Zhou W,Wang Z,Liu G,Neuberg D,Su L,Asomaning K,Hollis BW,Lynch TJ,Wain JC,Giovannucci E,Christiani DC.Circulating 25-hydroxyvitamin D, VDR polymorphisms, and survival in advanced non-small-cell lung cancer.J Clin Oncol. 2008 Dec 1;26(34):5596-602.
    18936471
  • Chin LJ,Ratner E,Leng S,Zhai R,Nallur S,Babar I,Muller RU,Straka E,Su L,Burki EA,Crowell RE,Patel R,Kulkarni T,Homer R,Zelterman D,Kidd KK,Zhu Y,Christiani DC,Belinsky SA,Slack FJ,Weidhaas JB.A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk.Cancer Res. 2008 Oct 15;68(20):8535-40.
    18922928
  • Sun P,Qian J,Zhang ZB,Wan JX,Wu F,Jin XP,Fan WW,Lu DR,Zhao NQ,Christiani DC,Xia ZL.Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population.Carcinogenesis. 2008 Dec;29(12):2325-9.
    18784359
  • Zhai R,Liu G,Asomaning K,Su L,Kulke MH,Heist RS,Nishioka NS,Lynch TJ,Wain JC,Lin X,Christiani DC.Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk.Carcinogenesis. 2008 Dec;29(12):2330-4.
    18780893
  • Ter-Minassian M,Zhai R,Asomaning K,Su L,Zhou W,Liu G,Heist RS,Lynch TJ,Wain JC,Lin X,De Vivo I,Christiani DC.Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.Carcinogenesis. 2008 Nov;29(11):2147-52.
    18757527
  • Kuo YC,Yu CL,Liu CY,Wang SF,Pan PC,Wu MT,Ho CK,Lo YS,Li Y,Christiani DC.A population-based, case-control study of green tea consumption and leukemia risk in southwestern Taiwan.Cancer Causes Control. 2009 Feb;20(1):57-65.
    18752033
  • Mazumdar M,Liu CY,Wang SF,Pan PC,Wu MT,Christiani DC.No association between parental or subject occupation and brain tumor risk.Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1835-7.
    18628439
  • Liu CY, Hsu YH, Pan PC, Wu MT, Ho CK, Su L, Xu X, Li Y, Christiani DC.Maternal and offspring genetic variants of AKR1C3 and the risk of childhood leukemia.Carcinogenesis. 2008 May;29(5):984-90.
    18339682
  • Asomaning K, Miller DP, Liu G, Wain JC, Lynch TJ, Su L, Christiani DC.Second hand smoke, age of exposure and lung cancer risk.Lung Cancer. 2008 Jul;61(1):13-20.
    18191495
  • Asomaning K,Reid AE,Zhou W,Heist RS,Zhai R,Su L,Kwak EL,Blaszkowsky L,Zhu AX,Ryan DP,Christiani DC,Liu G.MDM2 promoter polymorphism and pancreatic cancer risk and prognosis.Clin Cancer Res. 2008 Jun 15;14(12):4010-5.
    18559624
  • Lanuti M,Liu G,Goodwin JM,Zhai R,Fuchs BC,Asomaning K,Su L,Nishioka NS,Tanabe KK,Christiani DC.A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome.Clin Cancer Res. 2008 May 15;14(10):3216-22.
    18483390
  • Tse D,Zhai R,Zhou W,Heist RS,Asomaning K,Su L,Lynch TJ,Wain JC,Christiani DC,Liu G.Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk.Cancer Causes Control. 2008 Dec;19(10):1077-83.
    18478337
  • Liu G, Gurubhagavatula S, Zhou W, Wang Z, Yeap BY, Asomaning K, Su L, Heist R, Lynch TJ, Christiani DC.Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib.Pharmacogenomics J. 2008 Apr;8(2):129-38.
    17375033
  • Heist RS, Zhai R, Liu G, Zhou W, Lin X, Su L, Asomaning K, Lynch TJ, Wain JC, Christiani DC.VEGF polymorphisms and survival in early-stage non-small-cell lung cancer.J Clin Oncol. 2008 Feb 20;26(6):856-62.
    18281657
  • Zhai R, Liu G, Zhou W, Su L, Heist RS, Lynch TJ, Wain JC, Asomaning K, Lin X, Christiani DC.Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer.Clin Cancer Res. 2008 Jan 15;14(2):612-7.
    18223238
  • Wheatley-Price P, Asomaning K, Reid A, Zhai R, Su L, Zhou W, Zhu A, Ryan DP, Christiani DC, Liu G.Myeloperoxidase and superoxide dismutase polymorphisms are associated with an increased risk of developing pancreatic adenocarcinoma.Cancer. 2008 Mar 1;112(5):1037-42.
    18205184
  • Bradbury PA, Heist RS, Kulke MH, Zhou W, Marshall AL, Miller DP, Su L, Park S, Temel J, Fidias P, Sequist L, Lynch TJ, Wain JC, Shepherd FA, Christiani DC, Liu G.A rapid outcomes ascertainment system improves the quality of prognostic and pharmacogenetic outcomes from observational studies.Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):204-11.
    18199725
  • Harezlak J,Wu MC,Wang M,Schwartzman A,Christiani DC,Lin X.Biomarker discovery for arsenic exposure using functional data. Analysis and feature learning of mass spectrometry proteomic data.J Proteome Res. 2008 Jan;7(1):217-24.
    18173220
  • Liu G, Wheatley-Price P, Zhou W, Park S, Heist RS, Asomaning K, Wain JC, Lynch TJ, Su L, Christiani DC.Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk.Int J Cancer. 2008 Feb 15;122(4):915-8.
    17957785
  • Bajwa EK, Boyce PD, Januzzi JL, Gong MN, Thompson BT, Christiani DC.Biomarker evidence of myocardial cell injury is associated with mortality in acute respiratory distress syndrome.Crit Care Med. 2007 Nov;35(11):2484-90.
    18084839
  • Breton CV, Kile ML, Catalano PJ, Hoffman E, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC.GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study.Environ Health. 2007;6:39.
    18053222
  • McCarty KM, Smith TJ, Zhou W, Gonzalez E, Quamruzzaman Q, Rahman M, Mahiuddin G, Ryan L, Su L, Christiani DC.Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic related skin lesions.Carcinogenesis. 2007 Aug;28(8):1697-702.
    17470448
  • Zhai R, Gong MN, Zhou W, Thompson TB, Kraft P, Su L, Christiani DC.Genotypes and haplotypes of VEGF gene are associated with higher ARDS Mortality and lower VEGF plasma levels.Thorax. 2007 Aug;62(8):718-22.
    17289863
  • Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Janne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE, Wong KK.LKB1 modulates lung cancer differentiation and metastasis.Nature. 2007 Aug 16;448(7155):807-10.
    17676035
  • Sholl LM, John Iafrate A, Chou YP, Wu MT, Goan YG, Su L, Huang YT, Christiani DC, Chirieac LR.Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma.Mod Pathol. 2007 Oct;20(10):1028-35.
    17673923
  • Harezlak J,Wang M,Christiani D,Lin X.Quantitative quality-assessment techniques to compare fractionation and depletion methods in SELDI-TOF mass spectrometry experiments.Bioinformatics. 2007 Sep 15;23(18):2441-8.
    17626063
  • Breton CV, Zhou W, Kile ML, Houseman EA, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC.Susceptibility to arsenic-induced skin lesions from polymorphisms in base excision repair genes.Carcinogenesis. 2007 Jul;28(7):1520-5.
    17374727
  • Liu G, Zhou W, Yeap BY, Su L, Wain JC, Poneros JM, Nishioka NS, Lynch TJ, Christiani DC.XRCC1 and XPD Polymorphisms and Esophageal Adenocarcinoma Risk.Carcinogenesis. 2007 Jun;28(6):1254-8.
    17264068
  • Heist RS, Zhou W, Chirieac LR, Cogan-Drew T, Liu G, Su L, Neuberg D, Lynch TJ, Wain JC, Christiani DC.MDM2 polymorphism, survival, and histology in early-stage non-small-cell lung cancer.J Clin Oncol. 2007 Jun 1;25(16):2243-7.
    17538168
  • Zhang H, Hang J, Wang X, Zhou W, Sun B, Dai H, Su L, Christiani DC.TNF Polymorphisms Modify Endotoxin Exposure Associated Longitudinal Lung Function Decline.Occup Environ Med. 2007 Jun;64(6):409-13.
    17332138
  • Bajwa EK, Yu CL, Gong MN, Thompson BT, Christiani DC.Pre-B-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome*.Crit Care Med. 2007 May;35(5):1290-5.
    17414088
  • McCarty KM, Chen YC, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh YM, Su L, Smith T, Ryan L, Christiani DC.Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions.Environ Health Perspect. 2007 Mar;115(3):341-5.
    17431481
  • Christiani DC, Pao W, DeMartini JC, Linnoila RI, Malkinson AM, Onn A, Politi KA, Sharp M, Wong KK, Kim K.BAC consensus conference, November 4-6, 2004: epidemiology, pathogenesis, and preclinical models.J Thorac Oncol. 2006 Nov;1(9 Suppl):S2-7.
    17409996
  • Zhou W, Heist RS, Liu G, Asomaning K, Neuberg DS, Hollis BW, Wain JC, Lynch TJ, Giovannucci E, Su L, Christiani DC.Circulating 25-hydroxyvitamin D levels predict survival in early-stage non-small-cell lung cancer patients.J Clin Oncol. 2007 Feb 10;25(5):479-85.
    17290055
  • McMahon PM, Christiani DC.Computed tomography screening for lung cancer.BMJ. 2007 Feb 10;334(7588):271.
    17289689
  • McCarty KM, Ryan L, Houseman EA, Williams PL, Miller DP, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith T, Gonzalez E, Su L, Christiani DC.A case-control study of GST polymorphisms and arsenic related skin lesions.Environ Health. 2007;6:5.
    17284320
  • Zhai R, Zhou W, Gong MN, Thompson BT, Su L, Yu C, Kraft P, Christiani DC.Inhibitor kappaB-alpha haplotype GTC is associated with susceptibility to acute respiratory distress syndrome in Caucasians.Crit Care Med. 2007 Mar;35(3):893-8.
    17235259
  • Lamontagne AD, Christiani DC.Prevention of work-related cancers.New Solut. 2002;12(2):137-56.
    17208764
  • Zhou W, Heist RS, Liu G, Asomaning K, Miller DP, Neuberg DS, Wain JC, Lynch TJ, Christiani DC.Second hand smoke exposure and survival in early-stage non-small-cell lung cancer patients.Clin Cancer Res. 2006 Dec 1;12(23):7187-93.
    17145845
  • Gong MN, Zhou W, Williams PL, Thompson BT, Pothier L, Christiani DC.Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome.Crit Care Med. 2007 Jan;35(1):48-56.
    17133182
  • Zhou W, Heist RS, Liu G, Neuberg DS, Asomaning K, Su L, Wain JC, Lynch TJ, Giovannucci E, Christiani DC.Polymorphisms of vitamin d receptor and survival in early-stage non-small cell lung cancer patients.Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2239-45.
    17119052
  • Heist RS, Marshall AL, Liu G, Zhou W, Su L, Neuberg D, Lynch TJ, Wain J, Christiani DC.Matrix metalloproteinase polymorphisms and survival in stage I non-small cell lung cancer.Clin Cancer Res. 2006 Sep 15;12(18):5448-53.
    17000679
  • Fang SC, Eisen EA, Dai H, Zhang H, Hang J, Wang X, Christiani DC.Cancer mortality among textile workers in Shanghai, China: a preliminary study.J Occup Environ Med. 2006 Sep;48(9):955-8.
    16966963
  • Miller DP, Asomaning K, Liu G, Wain JC, Lynch TJ, Neuberg D, Su L, Christiani DC.An association between glutathione S-transferase P1 gene polymorphism and younger age at onset of lung carcinoma.Cancer. 2006 Oct 1;107(7):1570-7.
    16933328
  • Zhou W, Heist RS, Liu G, Park S, Neuberg DS, Asomaning K, Wain JC, Lynch TJ, Christiani DC.Smoking cessation before diagnosis and survival in early stage non-small cell lung cancer patients.Lung Cancer. 2006 Sep;53(3):375-80.
    16814423
  • Yu CL, Wang SF, Pan PC, Wu MT, Ho CK, Smith TJ, Li Y, Pothier L, Christiani DC,.Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure.Am J Epidemiol. 2006 Aug 1;164(3):200-7.
    16754633
  • Breton CV, Houseman EA, Kile ML, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC.Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions.Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):902-7.
    16702368
  • Wang X, Yano E, Wang Z, Wang M, Christiani DC.Adverse effects of asbestos exposure and smoking on lung function.Am J Ind Med. 2006 May;49(5):337-42.
    16570255
  • Christiani DC.Genetic susceptibility to lung cancer.J Clin Oncol. 2006 Apr 10;24(11):1651-2.
    16549817
  • Yu CL, Wang SF, Pan PC, Wu MT, Ho CK, Smith TJ, Li Y, Pothier LJ, Christiani DC.No association between residential exposure to petrochemicals and brain tumor risk.Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):3007-9.
    16365027
  • Su L, Zhou W, Asomaning K, Lin X, Wain JC, Lynch TJ, Liu G, Christiani DC.Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.Carcinogenesis. 2006 May;27(5):1024-1029.
    16311244
  • Zhou W, Park S, Liu G, Miller DP, Wang LI, Pothier L, Wain JC, Lynch TJ, Giovannucci E, Christiani DC.Dietary iron, zinc, and calcium and the risk of lung cancer.Epidemiology. 2005 Nov;16(6):772-9.
    16222167
  • Zhou W, Suk R, Liu G, Park S, Neuberg DS, Wain JC, Lynch TJ, Giovannucci E, Christiani DC.Vitamin D is associated with improved survival in early-stage non-small cell lung cancer patients.Cancer Epidemiol Biomarkers Prev. 2005 Oct;14(10):2303-9.
    16214909
  • Kile ML, Houseman EA, Rodrigues E, Smith TJ, Quamruzzaman Q, Rahman M, Mahiuddin G, Su L, Christiani DC.Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water.Cancer Epidemiol Biomarkers Prev. 2005 Oct;14(10):2419-26.
    16214926
  • Thurston SW, Liu G, Miller DP, Christiani DC.Modeling lung cancer risk in case-control studies using a new dose metric of smoking.Cancer Epidemiol Biomarkers Prev. 2005 Oct;14(10):2296-302.
    16214908
  • Liu G, Zhou W, Christiani DC.Molecular epidemiology of non-small cell lung cancer.Semin Respir Crit Care Med. 2005 Jun;26(3):265-72.
    16052427
  • Zhao X, Weir BA, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee JC, Naoki K, Richards WG, Sugarbaker D, Chen F, Rubin MA, Jnne PA, Girard L, Minna J, Christiani D, Li C, Sellers WR, Meyerson M.Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.Cancer Res. 2005 Jul 1;65(13):5561-70.
    15994928
  • Vrkonyi A, Kelsey K, Semey K, Bodell WJ, Lvay G, Mark E, Wain JC, Christiani DC, Wiencke JK.Polyphenol associated-DNA adducts in lung and blood mononuclear cells from lung cancer patients.Cancer Lett. 2006 May 8;236(1):24-31.
    15967573
  • Chen YC, Su HJ, Guo YL, Houseman EA, Christiani DC.Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer.Cancer Causes Control. 2005 Mar;16(2):75-81.
    15868449
  • Wang LI, Giovannucci EL, Hunter D, Neuberg D, Su L, Christiani DC.Dietary intake of Cruciferous vegetables, Glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population.Cancer Causes Control. 2004 Dec;15(10):977-85.
    15801482
  • Kim JY, Hecht SS, Mukherjee S, Carmella SG, Rodrigues EG, Christiani DC.A urinary metabolite of phenanthrene as a biomarker of polycyclic aromatic hydrocarbon metabolic activation in workers exposed to residual oil fly ash.Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):687-92.
    15767350
  • Su L, Zhou W, Park S, Wain JC, Lynch TJ, Liu G, Christiani DC.Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk.Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):567-70.
    15767330
  • Suk R, Gurubhagavatula S, Park S, Zhou W, Su L, Lynch TJ, Wain JC, Neuberg D, Liu G, Christiani DC.Polymorphisms in ERCC1 and grade 3 or 4 toxicity in non-small cell lung cancer patients.Clin Cancer Res. 2005 Feb 15;11(4):1534-8.
    15746057
  • Zhou W, Liu G, Park S, Wang Z, Wain JC, Lynch TJ, Su L, Christiani DC.Gene-smoking interaction associations for the ERCC1 polymorphisms in the risk of lung cancer.Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):491-6.
    15734977
  • Liu G, Zhou W, Park S, Wang LI, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC.The SOD2 Val/Val genotype enhances the risk of nonsmall cell lung carcinoma by p53 and XRCC1 polymorphisms.Cancer. 2004 Dec 15;101(12):2802-8.
    15534883
  • Zellos L, Christiani DC.Epidemiology, biologic behavior, and natural history of mesothelioma.Thorac Surg Clin. 2004 Nov;14(4):469-77, viii.
    15559053
  • Liu G, Zhou W, Wang LI, Park S, Miller DP, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC.MPO and SOD2 polymorphisms, gender, and the risk of non-small cell lung carcinoma.Cancer Lett. 2004 Oct 8;214(1):69-79.
    15331175
  • Zhou W, Gurubhagavatula S, Liu G, Park S, Neuberg DS, Wain JC, Lynch TJ, Su L, Christiani DC.Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.Clin Cancer Res. 2004 Aug 1;10(15):4939-43.
    15297394
  • Wang LI, Neuberg D, Christiani DC.Asbestos exposure, manganese superoxide dismutase (MnSOD) genotype, and lung cancer risk.J Occup Environ Med. 2004 Jun;46(6):556-64.
    15213518
  • Ryan L, Huang W, Thurston SW, Kelsey KT, Wiencke JK, Christiani DC.On the use of biomarkers for environmental health research.Statistical Methods in Medical Research. 2004 Jun;13(3):207-25.
    15198487
  • Gurubhagavatula S, Liu G, Park S, Zhou W, Su L, Wain JC, Lynch TJ, Neuberg DS, Christiani DC.XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy.J Clin Oncol. 2004 Jul 1;22(13):2594-601.
    15173214
  • Zhao X, Li C, Paez JG, Chin K, Jnne PA, Chen TH, Girard L, Minna J, Christiani D, Leo C, Gray JW, Sellers WR, Meyerson M.An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays.Cancer Res. 2004 May 1;64(9):3060-71.
    15126342
  • Kim JY, Mukherjee S, Ngo LC, Christiani DC.Urinary 8-hydroxy-2'-deoxyguanosine as a biomarker of oxidative DNA damage in workers exposed to fine particulates.Environ Health Perspect. 2004 May;112(6):666-71.
    15121508
  • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA.Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.N Engl J Med. 2004 May 20;350(21):2129-39.
    15118073
  • Jnne PA, Li C, Zhao X, Girard L, Chen TH, Minna J, Christiani DC, Johnson BE, Meyerson M.High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines.Oncogene. 2004 Apr 8;23(15):2716-26.
    15048096
  • Lange JH, Mastrangelo G, Fedeli U, Rylander R, Christiani DC.A benefit of reducing lung cancer incidence in women occupationally exposed to cotton textile dust.Am J Ind Med. 2004 Apr;45(4):388-9; author reply 390.
    15029574
  • Mukherjee S, Palmer LJ, Kim JY, Aeschliman DB, Houk RS, Woodin MA, Christiani DC.Smoking status and occupational exposure affects oxidative DNA injury in boilermakers exposed to metal fume and residual oil fly ash.Cancer Epidemiol Biomarkers Prev. 2004 Mar;13(3):454-60.
    15006923
  • Gong MN, Sai Y, Zhou W, Thompson BT, Xu LL, Christiani DC.Genotyping patients with recent blood transfusions.Epidemiology. 2003 Nov;14(6):744-7.
    14569193
  • Miller DP, Neuberg D, de Vivo I, Wain JC, Lynch TJ, Su L, Christiani DC.Smoking and the risk of lung cancer: susceptibility with GSTP1 polymorphisms.Epidemiology. 2003 Sep;14(5):545-51.
    14501269
  • Huang CI, Neuberg D, Johnson BE, Wei JY, Christiani DC.Expression of bcl-2 protein is associated with shorter survival in nonsmall cell lung carcinoma.Cancer. 2003 Jul 1;98(1):135-43.
    12833466
  • LaMontagne AD, Youngstrom RA, Lewiton M, Stoddard AM, Perry MJ, Klar JM, Christiani DC, Sorensen G.An exposure prevention rating method for intervention needs assessment and effectiveness evaluation.Appl Occup Environ Hyg. 2003 Jul;18(7):523-34.
    12791549
  • Su L, Sai Y, Fan R, Thurston SW, Miller DP, Zhou W, Wain JC, Lynch TJ, Liu G, Christiani DC.P53 (codon 72) and P21 (codon 31) polymorphisms alter in vivo mRNA expression of p21.Lung Cancer. 2003 Jun;40(3):259-66.
    12781424
  • Sorensen G, Stoddard AM, LaMontagne AD, Emmons K, Hunt MK, Youngstrom R, McLellan D, Christiani DC.A comprehensive worksite cancer prevention intervention: behavior change results from a randomized controlled trial (United States).J Public Health Policy. 2003;24(1):5-25.
    12760241
  • Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC.Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk.Cancer Epidemiol Biomarkers Prev. 2003 Apr;12(4):359-65.
    12692111
  • Miller DP, De Vivo I, Neuberg D, Wain JC, Lynch TJ, Su L, Christiani DC.Association between self-reported environmental tobacco smoke exposure and lung cancer: modification by GSTP1 polymorphism.Int J Cancer. 2003 May 10;104(6):758-63.
    12640684
  • Su L, Liu G, Zhou W, Xu LL, Miller DP, Park S, Lynch TJ, Wain JC, Christiani DC.No association between the p21 codon 31 serine-arginine polymorphism and lung cancer risk.Cancer Epidemiol Biomarkers Prev. 2003 Feb;12(2):174-5.
    12582031
  • Xu LL, Liu G, Miller DP, Zhou W, Lynch TJ, Wain JC, Su L, Christiani DC.Counterpoint: the myeloperoxidase -463G-->a polymorphism does not decrease lung cancer susceptibility in Caucasians.Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1555-9.
    12496043
  • Sorensen G, Stoddard AM, LaMontagne AD, Emmons K, Hunt MK, Youngstrom R, McLellan D, Christiani DC.A comprehensive worksite cancer prevention intervention: behavior change results from a randomized controlled trial (United States).Cancer Causes Control. 2002 Aug;13(6):493-502.
    12195637
  • Miller DP, Liu G, De Vivo I, Lynch TJ, Wain JC, Su L, Christiani DC.Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk.Cancer Res. 2002 May 15;62(10):2819-23.
    12019159
  • Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC.Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer.Cancer Res. 2002 Mar 1;62(5):1377-81.
    11888908
  • Zhou W, Liu G, Thurston SW, Xu LL, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC.Genetic polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancer.Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):15-21.
    11815396
  • Liu G, Miller DP, Zhou W, Thurston SW, Fan R, Xu LL, Lynch TJ, Wain JC, Su L, Christiani DC.Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.Cancer Res. 2001 Dec 15;61(24):8718-22.
    11751390
  • Wang LI, Miller DP, Sai Y, Liu G, Su L, Wain JC, Lynch TJ, Christiani DC.Manganese superoxide dismutase alanine-to-valine polymorphism at codon 16 and lung cancer risk.J Natl Cancer Inst. 2001 Dec 5;93(23):1818-21.
    11734599
  • Zhou W, Thurston SW, Liu G, Xu LL, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC.The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.Cancer Epidemiol Biomarkers Prev. 2001 May;10(5):461-6.
    11352855
  • Xu LL, Wain JC, Miller DP, Thurston SW, Su L, Lynch TJ, Christiani DC.The NAD(P)H:quinone oxidoreductase 1 gene polymorphism and lung cancer: differential susceptibility based on smoking behavior.Cancer Epidemiol Biomarkers Prev. 2001 Apr;10(4):303-9.
    11319169
  • Kim DH, Nelson HH, Wiencke JK, Christiani DC, Wain JC, Mark EJ, Kelsey KT.Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer.Oncogene. 2001 Mar 29;20(14):1765-70.
    11313923
  • Kim DH, Nelson HH, Wiencke JK, Zheng S, Christiani DC, Wain JC, Mark EJ, Kelsey KT.p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.Cancer Res. 2001 Apr 15;61(8):3419-24.
    11309302
  • Hirao T, Nelson HH, Ashok TD, Wain JC, Mark EJ, Christiani DC, Wiencke JK, Kelsey KT.Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer.Cancer Res. 2001 Jan 15;61(2):612-5.
    11212258
  • Fan R, Wu MT, Miller D, Wain JC, Kelsey KT, Wiencke JK, Christiani DC.The p53 codon 72 polymorphism and lung cancer risk.Cancer Epidemiol Biomarkers Prev. 2000 Oct;9(10):1037-42.
    11045785
  • Christiani DC.Smoking and the molecular epidemiology of lung cancer.Clin Chest Med. 2000 Mar;21(1):87-93, viii.
    10763091
  • Nelson HH, Christiani DC, Wiencke JK, Mark EJ, Wain JC, Kelsey KT.k-ras mutation and occupational asbestos exposure in lung adenocarcinoma: asbestos-related cancer without asbestosis.Cancer Res. 1999 Sep 15;59(18):4570-3.
    10493509
  • Lee BW, Wain JC, Kelsey KT, Wiencke JK, Christiani DC.Association between diet and lung cancer location.Am J Respir Crit Care Med. 1998 Oct;158(4):1197-203.
    9769282