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Paul E. Goss, FRCP, MB BCh, PhD

Professor, Department of Medicine, Harvard Medical School

Director, Breast Cancer Research, MGH Cancer Center, Massachusetts General Hospital

Contact Info

Paul Goss
Address not available.
Phone not available.
Email not available


Barbara Lampkin
Cancer Center
Massachusetts General Hospital
55 Fruit Street
Boston, MA, 02114
Mailstop: LRH-305A
Phone: 617-643-0744
Fax: 617-724-3166

DF/HCC Program Affiliation

Breast Cancer

Research Abstract

Dr. Paul Goss is the Research Director of the Breast Program at MGH, Co-Director of the DFHCC and Director Avon Center of Excellence. Dr. Goss' responsibilities include assisting and guiding the internal and National and International clinical and translational breast cancer research studies. He also leads large practice changing clinical trials in early stage breast cancer and in breast cancer prevention. Three areas are currently encompassed within these trials: optimizing endocrine therapy in treatment and prevention; application of anti-Her2 therapies in early stage disease and; studies of bone metabolism in early stage cancer therapies and most recently the role of rank ligand inhibition in the prevention of breast cancer recurrence and prevention of new primary disease. Translational areas of focus include: bone metabolism; tumor signatures; pharmacogenomics of toxicities and outcomes; mammographic density; quality of life; cost effectiveness. Dr. Goss leads a new International Program which focuses on: clinical trials; tissue repositories from clinical trials, intended for translational research studies; on-line data repository and statistical analyses; minorities, ethnicity and access to care; education. Dr. Goss also leads an active exchange program of international trainees and a growing global telemedicine forum.


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