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Alphonse G. Taghian, MD, PhD

Professor, Department of Radiation Oncology, Harvard Medical School

Associate in Radiation Oncology, Radiation Oncology, Massachusetts General Hospital

Contact Info

Alphonse Taghian
Massachusetts General Hospital
100 Blossom Street
Boston, MA, 02114
Mailstop: Cox 3
Phone: 617-726-6050
Fax: 617-726-3603


Not Available.

DF/HCC Program Affiliation

Breast Cancer

Research Abstract

The aim of my research is to develop molecular and physiologic markers which would predict the response of large breast cancer to chemotherapy. Why some palpable breast cancers respond to chemotherapy and others do not respond is still unclear. One of the reasons might be the drug does not reach the tumor cells. By studying the physiology of these tumors in vivo, we might understand the mechanisms of drug delivery. I am interested in studying the physiology of palpable breast cancer by measuring the pO2, blood flow and interstitial pressure of these tumors in patients.
My clinical research is in partial breast irradiation using a 3D conformal technique photons or protons. Instead of treating patients with 6 weeks of radiation to the whole breast, in some selected patients, one week of partial breast irradiation might be enough.


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