DF/HCC Program Affiliation

Breast Cancer
Cancer Genetics

Research Abstract

My research interest is the identification of novel diagnostics for breast cancer. Our effort is divided between genomics and proteomics. We have developed a novel high throughput methodology to detect germline DNA alterations in genes that are involved in risk of early onset cancer or somatic changes that impact tumor initiation, genesis and response to therapy. This methodology reduces the cost of sequencing by several orders of magnitude while maintaining the same sensitivity and specificity. We also have an ongoing effort to identify novel serum biomarkers by using mass spectrographic techniques. We are developing novel high throughput fractionation equipment to facilitate detection of rare protein biomarkers that indicate the presence of breast cancer.

Publications

View All Publications