DF/HCC Program Affiliation

Prostate Cancer
Kidney Cancer

Research Abstract

Our laboratory studies the molecular basis of human urologic tumors, including cancers of the prostate, bladder and kidney. We are in the process of identifying molecular and genetic changes of urologic cancers that correlate with the cancer disease behaviors, both clinically and pathologically. The long-term goal of these studies is to develop new diagnostic methods and therapeutic regiments.

Publications

• Jiang Z, Chu PG, Woda BA, Rock KL, Liu Q, Hsieh CC, Li C, Chen W, Duan HO, McDougal S, Wu CL.Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study.Lancet Oncol 2006 Jul;7(7):556-64.
  16814207
• Zhang H, Duan HO, Kirley SD, Zukerberg LR, Wu CL.Aberrant splicing of cables gene, a CDK regulator, in human cancers.Cancer Biol Ther 2005 Nov;4(11):1211-5.
  16177568
• Kohane DS, Ingelfinger JR, Nimkin K, Wu CL.Case records of the Massachusetts General Hospital. Case 16-2005. A nine-year-old girl with headaches and hypertension.N Engl J Med 2005 May 26;352(21):2223-31.
  15917388
• Cheng LL, Burns MA, Taylor JL, He W, Halpern EF, McDougal WS, Wu CL.Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy.Cancer Res 2005 Apr 15;65(8):3030-4.
  15833828
• Jiang Z, Wu CL, Woda BA, Iczkowski KA, Chu PG, Tretiakova MS, Young RH, Weiss LM, Blute RD, Brendler CB, Krausz T, Xu JC, Rock KL, Amin MB, Yang XJ.Alpha-methylacyl-CoA racemase: a multi-institutional study of a new prostate cancer marker.Histopathology 2
  15330799
• Wu CL, Yang XJ, Tretiakova M, Patton KT, Halpern EF, Woda BA, Young RH, Jiang Z.Analysis of alpha-methylacyl-CoA racemase (P504S) expression in high-grade prostatic intraepithelial neoplasia.Hum Pathol 2004 Aug;35(8):1008-13.
  15297968