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David E. Avigan, MD

Associate Professor, Department of Medicine, Harvard Medical School

Active Staff, Hematology-Oncology, Beth Israel Deaconess Medical Center

Contact Info

David Avigan
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA, 02215
Mailstop: KS 121
Phone: 617-667-9920
Fax: 617-667-9922
davigan@bidmc.harvard.edu

Assistant

Elana Grandberg
Program Coordinator
Heme Malignancy/Bone Marrow Transplant
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA, 02215
Mailstop: KS1361
Phone: 617-667-9932
Fax: 617-667-9922
egrandbe@bidmc.harvard.edu

DF/HCC Program Affiliation

Leukemia
Lymphoma and Myeloma

Research Abstract

My research interest lies in the field of tumor immunotherapy and its incorporation into bone marrow transplantation. Active projects include the development of dendritic cell tumor fusions to be used as tumor vaccines in a clinical trial for patients with breast cancer now in progression. I have also been exploring the number of immune reconstitution post-transplant and studying the impact of cytokine therapy with IL-12 and GM-CSF on this process. I am currently leading a new trial in the use of post-transplant Her2Neu antibody therapy assessing its impact on persistent residual disease. One group is investigating novel approaches to allogeneic transplantation including the use of non-myeloablative approaches.

Publications

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