DF/HCC Program Affiliation

Gynecologic Cancer
Cancer Epidemiology

Research Abstract

I am interested in how common genetic variation influences risk of ovarian and endoemtrial cancer. I am currently looking at how commonly occurring genetic variants, called polymorphisms, in the IGF and telomere maintenance pathways are associated with ovarian cancer risk in a population-based case-control study (Daniel Cramer, PI). In addition, I plan to evaluate how polymorphisms influence ovarian cancer survival and how telomere length may predict ovarian cancer risk. For endometrial cancer, I am studying whether a functional polymorphism (SNP309) in the MDM2 gene is associated with endometrial cancer risk in a well established cohort (the Nurses' Health Study).

Publications

• Terry KL, Willett WC, Rich-Edwards JW, Michels KB.A prospective study of infertility due to ovulatory disorders, ovulation induction, and incidence of breast cancer.Arch Intern Med 2006 Dec 11-25;166(22):2484-9.
  17159014
• Terry KL, De Vivo I, Titus-Ernstoff L, Shih MC, Cramer DW.Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer risk.Cancer Res 2005 Jul 1;65(13):5974-81.
  15994977
• Terry KL, De Vivo I, Titus-Ernstoff L, Sluss PM, Cramer DW.Genetic variation in the progesterone receptor gene and ovarian cancer risk.Am J Epidemiol 2005 Mar 1;161(5):442-51.
  15718480