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Geoffrey S. Young, MD

Assistant Professor, Department of Radiology, Harvard Medical School

Staff Physician, Radiology, Brigham And Women's Hospital

Contact Info

Geoffrey Young
Address not available.
Phone not available.
Email not available

Assistant

Eileen Walsh
Administrative Assistant
Radiology
Brigham And Women's Hospital
75 Francis Street
Boston, MA, 02115
Phone: 617-732-7260
emwalsh@partners.org

DF/HCC Program Affiliation

Neuro-Oncology
Cancer Imaging

Research Abstract

My current research focus centers on three areas: (1) Improvement in patient safety and diagnostic efficacy in neuroimaging diagnosis by application of quantitative image processing and informatics tools to computer assisted detection and diagnosis (CADD) of neurodegenerative, neurooncologic and neurovascular disease in collaboration with researchers from the Harvard Center for Bioinformatics (CBI), (2) Fusion of PET and optical molecular imaging data with MRI for improvement in multimodality imaging of brain tumor and neurodegeneration in human patients and transgenic rodent models in collaboration with researchers from the BWH Department of Nuclear Medicine, and the BWH Functional and Molecular Imaging Center (FMIC) and the Dana Farber Cancer Institute Department of Neuro-Oncology, (3) Novel MRI methods for assessment of brain tumor and neurodegeneration with MRI, including microvascular perfusion and capillary permeability, high b-value and tensor diffusion studies, and phase sensitive imaging. (4) Hyperpolarization Transfer MRI and Optical Imaging for Molecular Imaging of Brain Tumor and Neurodegeneration.
In addition, I collaborate with investigators in the CBI on a range of multiscale image registration and quantitation projects including correlation of MRI and light microscopy in transgenic animal models of aging, Alzheimer disease and vascular neurodegeneration, computational modeling of neuronal structure, advanced image-processing, semi-automated and automated segmentation and image registration and combined multi-data dimension display for clinical data reduction, assisted interpretation, and error reduction.
Previous Projects Include: (1) PET-MRI data fusion and Gamma-Knife Dosimetry-MRI data fusion for planning, monitoring and assessment of stereotactic radiosurgery of temporal lobe epilepsy; (2) Prospective use of diffusion weighted imaging in neurodegeneration to distinguish Creutzfeldt-Jakob Disease from other causes of dementia; (3) Quantitative diffusion weighted imaging, diffusion tensor imaging and deformation morphometry of Alzheimer Disease, CJD and Schizophrenia; (4) application of line scan diffusion weighted imaging to spine MRI for differentiation of benign and malignant compression fractures; (5) characterization of impairment of cerebrovascular autoregulation with Gadolinium bolus MR Perfusion imaging in hypertensive encephalopathy; (6) multidimensional MR spectroscopy, and (7) use of high-temperature superconducting MRI receive coils for human head and neck imaging.

Publications

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