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Roy B. Tishler, MD, PhD

Associate Professor, Department of Radiation Oncology, Harvard Medical School

Assistant Professor, Radiation Oncology Department, Dana-Farber Cancer Institute

Contact Info

Roy Tishler
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Mailstop: HX0033
Phone: 617-632-3591
Fax: 617-632-4247
roy_tishler@dfci.harvard.edu

Assistant

Andrea Formosi
Brigham And Women's Hospital
Phone: 617-732-7906
aformosi@partners.org

DF/HCC Program Affiliation

Head and Neck Cancer

Research Abstract

My laboratory research focuses on the molecular mechanisms of interaction of radiation and chemotherapeutic drugs, particularly the taxanes. Current projects are examining the role of the tumor suppressor p53 and bcl-2 related proteins on the interaction of Taxol and radiation in human tumor cells. We are also examining other chemotherapy-radiaton interactions, as well as different aspects of radiation-dependent gene induction. My clinical reasearch interests are: 1) use of combined modality treatment for organ preservation in the treatment of head and neck cancers 2) role of radiation sensitizers and chemotherapeutic drugs in treatment of tumors of the central nervous system.

Publications

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