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Myles Brown, MD

Professor, Department of Medicine, Harvard Medical School

Physician, Oncology, Brigham And Women's Hospital

Professor of Medicine, Medical Oncology, Dana-Farber Cancer Institute

Contact Info

Myles Brown
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Mailstop: Dana 730
Phone: 617-632-3948
Fax: 617-582-8501
Myles_Brown@dfci.harvard.edu

Assistant

Claudia Steele
Administrative Assistant
Medical Oncology
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Mailstop: Dana 730
Phone: 617-582-7646
Fax: 617-582-8501
claudia_steele@dfci.harvard.edu

DF/HCC Program Affiliation

Prostate Cancer
Breast Cancer

Research Abstract

Dr. Brown's research laboratory focuses on elucidating the epigenetic factors underlying the action of steroid hormones. This work has important implications both for normal physiology and for the treatment of hormone dependent malignancies including breast and prostate cancer. He is recognized for three seminal discoveries. His lab opened the steroid receptor coregulator field, illuminated the dynamic nature of receptor and coregulator interaction with the genome and elucidated the importance of epigenetically determined distant cis-regulatory steroid receptor binding sites. His contributions have uniquely reformulated the understanding of steroid hormone action in normal physiology and in hormone-dependent cancer.

Publications

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