DF/HCC Program Affiliation

Lung Cancer

Research Abstract

My laboratory has been involved in the cloning and characterization of novel molecules playing a role in oncogenesis in order to define new markers for malignant cell populations and also to better understand tumor biology.

Publications

• Fu Y, Comella N, Tognazzi K, Brown LF, Dvorak HF, Kocher O.Cloning of DLM-1, a novel gene that is up-regulated in activated macrophages, using RNA differential display.Gene 1999 Nov 15;240(1):157-63.
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• Kocher O, Comella N, Gilchrist A, Pal R, Tognazzi K, Brown LF, Knoll JH.PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein.Lab Inv
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• Abu-Jawdeh G, Comella N, Tomita Y, Brown LF, Tognazzi K, Sokol SY, Kocher O.Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy.Lab Invest 1999 Apr;79(4):439-47.
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