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F. Stephen Hodi, MD

Associate Professor, Department of Medicine, Harvard Medical School

Assistant Professor of Medicine, DF/HCC, Dana-Farber Cancer Institute

Contact Info

F. Stephen Hodi
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02215
Phone: 617-632-5053
Fax: 617-582-7992


Paulette Sandiford
Administrative Assistant
Dana-Farber Cancer Institute
450 Brookline Avenue
Boston, MA, 02115
Phone: 617-632-4715
Fax: 617-632-6727

DF/HCC Program Affiliation

Cutaneous Oncology and Melanoma, Co-Leader
Cancer Immunology

DF/HCC Associations

Member, Clinical Science Coordinating Committee
Member, Center Scientific Council

Research Abstract

We performed a clinical trial of vaccination with lethally irradiated, autologous melanoma cells expressing human GM-CSF. Vaccination elicits a striking infiltrate of pre-existing metastatic lesions with large numbers of lymphocytes, plasma cells, macrophages, and eosinophils, resulting in tumor destruction, fibrosis and edema. From this foundation we are determining the melanoma antigens that have stimulated specific T and B cell responses in vaccinated patients through molecular analyses.


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