Winter 2017 Publications Mixtape

Here is a selection of recent collaborative publications involving DF/HCC authors for your reading pleasure.

Diffusion of Bevacizumab Across Oncology Practices: An Observational Study.
Med Care. 2017 Nov 10.
Keating NL (BWH), Huskamp HA, Schrag D (DFCI), McWilliams JM, McNeil BJ (HMS), Landon BE, Chernew ME, Normand ST.
PMID: 29135615

Use of Surveillance Mammography Among Older Breast Cancer Survivors by 
J Clin Oncol. 2017 Sep 20.
Freedman RA (DFCI), Keating NL (BWH), Pace LE (BWH), Lii J, McCarthy EP (BIDMC), Schonberg MA (BIDMC).
PMCID: PMC5597254

Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer.
Nat Commun. 2017 Sep 4.
Tyekucheva S, Bowden M, Bango C, Giunchi F, Huang Y, Zhou C, Bondi A, Lis R, Van Hemelrijck M, Andrén O, Andersson SO, Watson RW, Pennington S, Finn SP, Martin NE (DFCI), Stampfer MJ (BWH), Parmigiani G (DFCI), Penney KL (BWH), Fiorentino M, Mucci LA (HSPH), Loda M (DFCI).
PMCID: PMC5583238

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.
Nat Genet. 2017 Oct
Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW (DFCI), Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR (DFCI), Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA (MGH), Laird PW, Shen H, Ellisen LW (MGH), D'Andrea AD (DFCI), Chanock SJ, Foulkes WD, Getz G (MGH).
PMID: 28825726

Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.
JAMA Oncol. 2017 Jun 1.
Campbell JD, Lathan C (DFCI), Sholl L (BWH), Ducar M, Vega M, Sunkavalli A, Lin L, Hanna M, Schubert L, Thorner A, Faris N, Williams DR (HSPH), Osarogiagbon RU, van Hummelen P, Meyerson M (DFCI), MacConaill L.
PMCID: PMC5464986

Cyclin D-CDK4 kinase destabilizes PD-L1 via Cul3(SPOP) to control cancer immune surveillance.
Nature. 2017 Nov 16.
Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ (DFCI), Sicinski P (DFCI), Wei W (BIDMC).
PMID: 29160310

A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.
Am J. Hematol. 2017 Nov 9.
DeAngelo DJ (DFCI), Brunner AM (MGH), Werner L, Avigan D (BIDMC), Fathi AT (HMS), Sperling AS, Washington A, Stroopinsky D, Rosenblatt J (BIDMC), McMasters M, Luptakova K, Wadleigh M, Steensma DP (DFCI), Hobbs GS, Attar EC, Amrein PC (MGH), Ebert BL (DFCI), Stone RM (DFCI), Ballen KK.
PMID: 29119643

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.
Nat Commun. 2017 Nov 6.
Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD (DFCI), Stover DG, Parsons HA (DFCI), Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ (DFCI), Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC (DFCI), Tolaney SM (DFCI), Van Allen EM (DFCI), Winer EP (DFCI), Lin NU (DFCI), Nakabayashi M, Taplin ME (DFCI), Johannessen CM, Garraway LA (DFCI), Golub TR (DFCI), Boehm JS, Wagle N (DFCI), Getz G (MGH), Love JC, Meyerson M (DFCI).
PMCID: PMC5673918

CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T
Cell Activation.
Cancer Discov. 2017 Nov 3.
Deng J, Wang ES, Jenkins RW, Li S, Dries R, Yates K, Chhabra S, Huang W, Liu H, Aref AR, Ivanova E, Paweletz CP, Bowden M, Zhou CW, Herter-Sprie GS, Sorrentino JA, Bisi JE, Lizotte PH, Merlino AA, Quinn MM, Bufe LE, Yang A, Zhang Y, Zhang H, Gao P, Chen T, Cavanaugh ME, Rode AJ, Haines E, Roberts PJ, Strum JC, Richards WG (BWH), Lorch JH (DFCI), Parangi S, Gunda V, Boland GM, Bueno R (BWH), Palakurthi S, Freeman GJ (DFCI), Ritz J (DFCI), Haining WN (DFCI), Sharpless NE, Arthanari H, Shapiro GI (DFCI), Barbie DA (DFCI), Gray NS (DFCI), Wong KK (DFCI).
PMID: 29101163

Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma.
JAMA Oncol. 2017 Nov 2.
Qian ZR, Rubinson DA, Nowak JA, Morales-Oyarvide V, Dunne RF, Kozak MM, Welch MW, Brais LK, Da Silva A, Li T, Li W, Masuda A, Yang J, Shi Y, Gu M, Masugi Y, Bui J, Zellers CL, Yuan C, Babic A, Khalaf N, Aguirre A, Ng K (DFCI), Miksad RA (BIDMC), Bullock AJ (BIDMC), Chang DT, Tseng JF, Clancy TE (BWH), Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar M, Wollison B, Laing A, Hahn WC (DFCI), Meyerson M (DFCI), Fuchs CS (DFCI), Ogino S (DFCI), Hornick JL (BWH), Hezel AF, Koong AC, Wolpin BM (DFCI).
PMID: 29098284

LesionTracker: Extensible Open-Source Zero-Footprint Web Viewer for Cancer Imaging Research and Clinical Trials.
Cancer Res. 2017 Nov 1.
Urban T, Ziegler E, Lewis R, Hafey C, Sadow C, Van den Abbeele AD (DFCI), Harris GJ (MGH).
PMCID: PMC5679226

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.
Nat Commun. 2017 Oct 30.
Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR (DFCI), Subramanian A, Ma'ayan A, Sorger PK (HMS).
PMCID: PMC5662764

Residual Convolutional Neural Network for Determination of IDH Status in Low- and High-grade Gliomas from MR Imaging.
Clin Cancer Res. 2017 Nov 22.
Chang K, Bai HX, Zhou H, Su C, Bi WL, Agbodza E, Kavouridis VK, Senders JT, Boaro A, Beers AL, Zhang B, Capellini A, Liao W, Shen Q, Li X, Xiao B, Cryan J, Ramkissoon S, Ramkissoon L, Ligon KL (DFCI), Wen PY (BWH), Bindra RS, Woo JH, Arnaout O, Gerstner E, Zhang PJ, Rosen B (MGH), Yang L, Huang RY, Kalpathy-Cramer J.
PMID: 29167275

A single-cell survey of the small intestinal epithelium.
Nature. 2017 Nov 16.
Haber AL, Biton M, Rogel N, Herbst RH, Shekhar K, Smillie C, Burgin G, Delorey TM, Howitt MR, Katz Y, Tirosh I, Beyaz S, Dionne D, Zhang M, Raychowdhury R, Garrett WS (HSPH), Rozenblatt-Rosen O, Shi HN, Yilmaz O, Xavier RJ (MGH), Regev A
PMID: 29144463