DF/HCC SPORE Application in T Cell Lymphoma

January 17, 2017


REQUEST FOR PRE-APPLICATIONS:
 Research Projects/Pilot Project Proposals in T cell Lymphoma

AWARD AMOUNT: Full projects would be granted at a level up to $150K in yearly direct costs for up to 5 years; pilot projects would be granted at a level up to $75K in yearly direct costs for up to 1-2 years

APPLICATION DEADLINE: February 10, 2017

ANTICIPATED AWARD DATES: April 2018 

The Lymphoma & Myeloma Program at Dana-Farber/Harvard Cancer Center (DF/HCC) is seeking scientific projects for potential inclusion in a new application for a National Cancer Institute (NCI)-sponsored SPORE grant focused on T cell lymphomas to be submitted on May 19, 2017.  Unlike B cell lymphomas (the subject of all currently funded Lymphoma SPOREs), T cell lymphomas are less common and less well understood; they include both Cutaneous T Cell Lymphomas (CTCL) and Peripheral T Cell Lymphomas (PTCL). Novel approaches involving immunotherapy and approaches that could be ultimately translated into clinical trials for these diseases are especially encouraged.  We are accepting both full project and pilot project proposals. Full projects are for the 5-year grant period, and pilot projects are for a 1-2 year period.

Applicants must be faculty members at the level of Instructor or higher. While the proposed research may be basic or clinical, bench-to-bedside or bedside-to-bench strategies must be addressed in the application, as the ultimate purpose of the program is to promote translational research and clinical trials in CTCL and PTCL.

We are seeking pre-applications in the form of a 2-page proposal that contains background, specific aims, research plan and plans for translation (see below). These pre-applications will be judged on their scientific merit and translational potential. Some pre-applications may be selected to present their proposal at a project review session (time and place to be determined). Up to 5 projects may ultimately be selected for inclusion in the new SPORE application. Full projects would be granted at a level up to $150K in yearly direct costs for up to 5 years; pilot projects would be granted at a level up to $75K in yearly direct costs for up to 1-2 years (possible start date April 2018). The awardees would be expected to attend SPORE activities (meetings, retreats, research presentations). Women and minority candidates are encouraged to apply.

Pre-applications are due February 10, and should consist of the following, assembled as one PDF:

  • 1. NIH Biosketch for all key personnel
  • 2. Current Other Support pages for all key personnel
  • 3. A brief research proposal of approximately 1-2 pages that is structured as follows: 
    • A. Background
    • B. Specific Aim
    • C. Research Plan
    • D. Plan for Translation to Clinical Application
  • 4. Appendix with reprints, etc. are permitted

Should you wish to discuss ideas or concepts, please contact Thomas Kupper and David Weinstock at: tkupper@bwh.harvard.edu  and DavidM_Weinstock@dfci.harvard.edu

Please submit pre-applications to: deborah_goff@dfci.harvard.edu by February 10, 2017.