Kidney Cancer Program and SPORE Request for Translational Research Projects

December 11, 2018

The Kidney Cancer Program of the Dana-Farber/Harvard Cancer Center seeks translational research projects for potential inclusion in the 5-year competitive renewal of the DF/HCC Kidney Cancer Specialized Program on Research Excellence (SPORE) grant. Applicants must be on the faculty at Harvard Medical School at the level of Assistant Professor or higher. Proposals will be accepted from investigators leading existing projects and pilot projects as well as currently non-SPORE funded investigators. While the proposed research can be basic or clinical, bench-to- bedside and bedside-to-bench strategies need to be addressed, since the purpose of this program is to promote translational research in kidney cancer. All basic research supported by the SPORE must have a plan for translation into application or studies in humans within the 5 years of the grant proposal. In order to facilitate this translation, projects should be co-led by a basic and a clinically oriented scientist.

We are seeking pre-applications in the form of a 2-4-page proposal that contains background, specific aims, research plan and plans for translation (see below). These pre-applications will be judged on their scientific merit, translational potential, relevance to kidney cancer, qualifications of the research team and the potential fit within the overall activities of the DF/HCC Kidney Cancer Program and SPORE. Some pre-applications will be selected for presentation at project review sessions to be held during mid-spring. Final project selections will be made by the Kidney Cancer Program Governance Committee in conjunction with its Internal Advisory Board in the summer of 2019. Ultimately, 4 projects will be included in the final SPORE application that is due in January 2020. If the SPORE grant is funded, the project awards will be granted at a level of approximately $100-150,000 in yearly direct costs for 2-5 years. The awardees will become members of the DF/HCC Kidney Cancer Program and SPORE and would be expected to attend SPORE activities (meetings, retreats, research presentations). Women and minority candidates are encouraged to apply.

Applications must contain the following components:

  1. Abbreviated Research Plan including the Specific Aims, Background and Significance, Preliminary and Data, and Experimental Methods (not to exceed 4 pages
  2. Translational goals of the project, potential application to kidney cancer and anticipated timeline (1 page)
  3. List and descriptions of key personnel and roles on the project
  4. Applicant address; E-mail and telephone contact information.

Application packages are due Friday, February 15th, 2019 in PDF format and submitted electronically to Tara at: tjohnst1@bidmc.harvard.edu.