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Request for Applications: Developmental Research Award in Multiple Myeloma

The objectives of the Developmental Research Program are to provide a continuous flow of new ideas and projects to stimulate myeloma research in the context of the Myeloma SPORE. It encourages new research directions and methodologies and facilitates collaborations. By providing initial support to pilot projects, it will foster the development of new translational projects.  It also allows the Myeloma SPORE to have participation and recruitment of investigators not only from the DF/HCC, but also including outside institutions such as Mayo Clinic, and H. Lee Moffitt Cancer Center. This Program will rely on scientific and programmatic review by a Developmental Research Committee, which will assure selection of the most promising and highest quality projects with high likelihood of translational impact.

Application

The completed application should be submitted no later than July 15, 2014.

An electronic version of the application, in pdf format only, should be sent to: nikhil_munshi@dfci.harvard.edu.  A scanned copy of the signed first page should also be included in the mail.

To confirm receipt of the application, please provide e-mail with an automated reply option.

The application should contain the following components: 

  1. Application Front Page with signatures
  2. Research Abstract ( ˝ page)
  3. Budget with justification
  4. Research Proposal to include Background and Relevance, Specific Aims, Preliminary Data, and Experimental Methods. Not to exceed 5 pages exclusive of the literature cited.
  5. Translational Objectives of the Proposed Research (1/2 page)
  6. NIH Biosketch including other Support pages of the Applicant
  7. Appendix. 2 reprints may be included.  Figures may not be included in the Appendix.


Budget

Developmental Research projects will be up to $86,000 direct cost/year for 1 year. In general, these awards will support awardees for up to 1 year of funding with a chance of reapplication for the 2nd year based on merit. The money can be used toward the awardees’ salary, research supplies, and/or salaries of research assistants or technicians. Detailed breakdown of the budget with justification is requested.

Criteria for Selection

Candidates may be either clinicians with an MD degree who are interested in translational research, or scientists with a PhD degree (or an equivalent higher degree), who are interested in the application of basic science to the problem of therapy of myeloma.  Selection will be made according to the following criteria:

  1. The quality and novelty of the science proposed
  2. Translational nature of the proposed project
  3. The dedication of the candidate to a particular clinical problem in myeloma, and his or her likelihood to remain interested in translational cancer research in myeloma in the future.
  4. The track record of the individual and his/her potential to contribute to the field.
  5. The programmatic needs of the SPORE.  The application should not propose studies already covered in the ongoing SPORE related research. 


AWARD CONDITIONS AND REPORTING

The monetary award is provided to the awardees’ sponsoring institution for the direct support of the recipient's work during the award year. The award may be used for laboratory supplies for the research proposed.  No more than $500 may be requested for travel directly related to the research project.  Institutional overhead will not be permitted.

  • At the start of the grant cycle the initial 6 months of funding is provided.
  • After six months, the recipient is required to submit a brief written summary of the research conducted as well as a detailed account of the use of award funds.  Upon review and approval of award recipient’s summary, the second six months of funding is provided.  Should the recipient’s work not be considered acceptable by the award committee, funding will cease.
  • A final report is also required.
  • Recipients are expected to credit the DF/HCC MM SPORE in any publications/presentations that result from the funded work.