DF/HCC Program Affiliation

Member, Neuro-Oncology Program
Member, Cancer Immunology Program

Research Abstract

My research focus is on the study of antitumor immunity in patients with malignant brain tumors. In particular, we are initiating phase I clinical trials using immunotherpy approaches and, in turn, performing detailed serological and tissue-based analyses of antitumor immune responses. One focus is on the discovery of novel glioma-associated antigens and monitoring antibody and T- lymphocyte responses to them as patients are treated.

Publications

• Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, Batchelor TT, Futreal PA, Stratton MR, Curry WT, Iafrate AJ, Louis DN. Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clin Cancer Res 2007 Apr 1; 13(7):2038-45
  PMID: 17404084
• Verhey LJ, Chen CC, Chapman P, Loeffler J, Curry WT. Single-fraction stereotactic radiosurgery for intracranial targets. Neurosurg Clin N Am 2006 Apr; 17(2):79-97
  PMID: 16793501
• Curry WT, Cosgrove GR, Buchbinder BR, Ojemann RG. Resection of a dominant-hemisphere intraventricular meningioma facilitated by functional magnetic resonance imaging. Case report. Neurosurg Focus 2001; 10(6):E1
  PMID: 16724819
• Curry WT, Cosgrove GR, Hochberg FH, Loeffler J, Zervas NT. Stereotactic interstitial radiosurgery for cerebral metastases. J Neurosurg 2005 Oct; 103(4):630-5
  PMID: 16266044
• Curry WT, McDermott MW, Carter BS, Barker FG. Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload. J Neurosurg 2005 Jun; 102(6):977-86
  PMID: 16028755
• Barker FG, Curry WT, Carter BS. Surgery for primary supratentorial brain tumors in the United States, 1988 to 2000: the effect of provider caseload and centralization of care. Neuro-oncol 2005 Jan; 7(1):49-63
  PMID: 15701282
• Curry WT, Butler WE, Barker FG. Rapidly rising incidence of cerebrospinal fluid shunting procedures for idiopathic intracranial hypertension in the United States, 1988-2002. Neurosurgery 2005 Jul; 57(1):97-108; discussion 97-108
  PMID: 15987545
• Curry WT, Hoh BL, Amin-Hanjani S, Eskandar EN. Spinal epidural abscess: clinical presentation, management, and outcome. Surg Neurol 2005 Apr; 63(4):364-71; discussion 371
  PMID: 15808726
• Curry WT, Sethi MK, Ogilvy CS, Carter BS. Factors associated with outcome after hemicraniectomy for large middle cerebral artery territory infarction. Neurosurgery 2005 Apr; 56(4):681-92; discussion 681-92
  PMID: 15792506
• Hoh BL, Curry WT, Carter BS, Ogilvy CS. Computed tomographic demonstrated infarcts after surgical and endovascular treatment of aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien) 2004 Nov; 146(11):1177-83
  PMID: 15349755