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Dimitrios Spentzos, M.D. M.M.Sc.


  • Duan Z, Shen J, Yang X, Yang P, Osaka E, Choy E, Cote G, Harmon D, Zhang Y, Nielsen GP, Spentzos D, Mankin H, Hornicek F.Prognostic significance of miRNA-1 (miR-1) expression in patients with chordoma.J Orthop Res. 2014 May;32(5):695-701.
  • Kelly AD, Hill KE, Correll M, Hu L, Wang Y, Rubio R, Duan S, Quackenbush J, Spentzos D.Next-generation sequencing and microarray-based interrogation of microRNAs from formalin-fixed, paraffin-embedded tissue: Preliminary assessment of cross-platform concordance.Genomics. 2013 Apr 3.
  • Schwede M, Spentzos D, Bentink S, Hofmann O, Haibe-Kains B, Harrington D, Quackenbush J, Culhane AC.Stem Cell-Like Gene Expression in Ovarian Cancer Predicts Type II Subtype and Prognosis.PLoS ONE. 2013;8(3):e57799.
  • Kelly AD, Haibe-Kains B, Janeway KA, Hill KE, Howe E, Goldsmith J, Kurek K, Perez-Atayde AR, Francoeur N, Fan JB, April C, Schneider H, Gebhardt MC, Culhane A, Quackenbush J, Spentzos D.MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32.Genome Med. 2013 Jan 22;5(1):2.
  • Fountzilas E, Kelly AD, Perez-Atayde AR, Goldsmith J, Konstantinopoulos PA, Francoeur N, Correll M, Rubio R, Hu L, Gebhardt MC, Quackenbush J, Spentzos D.A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study.BMC Genomics. 2012;13:332.
  • Konstantinopoulos PA, Spentzos D, Karlan BY, Taniguchi T, Fountzilas E, Francoeur N, Levine DA, Cannistra SA.Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.J Clin Oncol. 2010 Aug 1;28(22):3555-61.
  • Konstantinopoulos PA, Fountzilas E, Goldsmith JD, Bhasin M, Pillay K, Francoeur N, Libermann TA, Gebhardt MC, Spentzos D.Analysis of multiple sarcoma expression datasets: implications for classification, oncogenic pathway activation and chemotherapy resistance.PLoS ONE. 2010;5(4):e9747.
  • Rosenblatt J, Wu Z, Vasir B, Zarwan C, Stone R, Mills H, Friedman T, Konstantinopoulos PA, Spentzos D, Ghebremichael M, Stevenson K, Neuberg D, Levine JD, Joyce R, Tzachanis D, Boussiotis V, Kufe D, Avigan D.Generation of Tumor-specific T Lymphocytes Using Dendritic Cell/Tumor Fusions and Anti-CD3/CD28.J Immunother.;33(2):155-66.
  • Burga LN,Tung NM,Troyan SL,Bostina M,Konstantinopoulos PA,Fountzilas H,Spentzos D,Miron A,Yassin YA,Lee BT,Wulf GM.Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers.Cancer Res. 2009 Feb 15;69(4):1273-8.
  • Konstantinopoulos PA,Fountzilas E,Pillay K,Zerbini LF,Libermann TA,Cannistra SA,Spentzos D.Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer.BMC Med Genomics. 2008;1:59.
  • Konstantinopoulos PA, Spentzos D, Cannistra SA.Gene-expression profiling in epithelial ovarian cancer.Nat Clin Pract Oncol. 2008 Oct;5(10):577-87. Review.
  • Tworoger SS,Spentzos D,Grall FT,Liebermann TA,Hankinson SE.Reproducibility of proteomic profiles over 3 years in postmenopausal women not taking postmenopausal hormones.Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1480-5.
  • Zinkin NT, Grall F, Bhaskar K, Otu HH, Spentzos D, Kalmowitz B, Wells M, Guerrero M, Asara JM, Libermann TA, Afdhal NH.Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease.Clin Cancer Res. 2008 Jan 15;14(2):470-7.
  • Jones J, Otu HH, Grall F, Spentzos D, Can H, Aivado M, Belldegrun AS, Pantuck AJ, Libermann TA.Proteomic identification of interleukin-2 therapy response in metastatic renal cell cancer.J Urol. 2008 Feb;179(2):730-6.
  • Spentzos D, Cannistra SA, Grall F, Levine DA, Pillay K, Libermann TA, Mantzoros CS.IGF axis gene expression patterns are prognostic of survival in epithelial ovarian cancer.Endocr Relat Cancer. 2007 Sep;14(3):781-90.
  • Spentzos D, Levine DA, Kolia S, Otu H, Boyd J, Libermann TA, Cannistra SA.Unique gene expression profile based on pathologic response in epithelial ovarian cancer.J Clin Oncol. 2005 Nov 1;23(31):7911-8.
  • Jones J, Otu H, Spentzos D, Kolia S, Inan M, Beecken WD, Fellbaum C, Gu X, Joseph M, Pantuck AJ, Jonas D, Libermann TA.Gene signatures of progression and metastasis in renal cell cancer.Clin Cancer Res. 2005 Aug 15;11(16):5730-9.
  • Aivado M, Spentzos D, Alterovitz G, Otu HH, Grall F, Giagounidis AA, Wells M, Cho JY, Germing U, Czibere A, Prall WC, Porter C, Ramoni MF, Libermann TA.Optimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling.Clin Chem Lab Med. 2005;43(2):133-40.
  • Spentzos D, Levine DA, Ramoni MF, Joseph M, Gu X, Boyd J, Libermann TA, Cannistra SA.Gene expression signature with independent prognostic significance in epithelial ovarian cancer.J Clin Oncol. 2004 Dec 1;22(23):4648-58.
  • Spentzos D, Mantzoros C, Regan MM, Morrissey ME, Duggan S, Flickner-Garvey S, McCormick H, DeWolf W, Balk S, Bubley GJ.Minimal effect of a low-fat/high soy diet for asymptomatic, hormonally naive prostate cancer patients.Clin Cancer Res. 2003 Aug 15;9(9):3282-7.
  • Georgiadis E, Mantzoros CS, Evagelopoulou C, Spentzos D.Adult height and menarcheal age of young women in Greece.Ann Hum Biol. 1997 Jan-Feb;24(1):55-9.