Shuji Ogino, MD, PhD, MS (Epidemiology)

Publications

• Baba Y, Nosho K, Shima K, Hayashi M, Meyerhardt JA, Chan AT, Giovannucci E, Fuchs CS, Ogino S.Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.Cancer. 2011 Apr 1;117(7):1399-408.
  21425139
• Morikawa T, Baba Y, Yamauchi M, Kuchiba A, Nosho K, Shima K, Tanaka N, Huttenhower C, Frank DA, Fuchs CS, Ogino S.STAT3 Expression, Molecular Features, Inflammation Patterns, and Prognosis in a Database of 724 Colorectal Cancers.Clin Cancer Res. 2011 Mar
  21310826
• Chan AT, Ogino S, Giovannucci EL, Fuchs CS.Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs.Gastroenterology. 2011 Mar;140(3):799-808.e2.
  21115010
• Ogino S, Chan AT, Fuchs CS, Giovannucci E.Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field.Gut. 2011 Mar;60(3):397-411. Review.
  21036793
• Shima K, Morikawa T, Baba Y, Nosho K, Suzuki M, Yamauchi M, Hayashi M, Giovannucci E, Fuchs CS, Ogino S.MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.Cancer Causes Control. 2011 Feb;22(2):301-9.
  21140203
• Shima K, Nosho K, Baba Y, Cantor M, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.Int J Cancer. 2011 Mar 1
  20473920
• Baba Y, Nosho K, Shima K, Huttenhower C, Tanaka N, Hazra A, Giovannucci EL, Fuchs CS, Ogino S.Hypomethylation of the IGF2 DMR in Colorectal Tumors, Detected by Bisulfite Pyrosequencing, Is Associated With Poor Prognosis.Gastroenterology. 2010 Dec;139(6):1
  20682317
• Tanaka N, Huttenhower C, Nosho K, Baba Y, Shima K, Quackenbush J, Haigis KM, Giovannucci E, Fuchs CS, Ogino S.Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.Am J Pathol. 2
  21037082
• Baba Y, Nosho K, Shima K, Hayashi M, Meyerhardt JA, Chan AT, Giovannucci E, Fuchs CS, Ogino S.Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.Cancer. 2010 Nov 8.
  21061337
• Chan AT, Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Madden K, Poss K, Ranieri A, Shue D, Kucherlapati R, Fuchs CS, Ogino S.Cathepsin B Expression and Survival in Colon Cancer: Implications for Molecular Detection of Neoplasia.Cancer Epidemiol
  20833970
• Nosho K, Baba Y, Tanaka N, Shima K, Hayashi M, Meyerhardt JA, Giovannucci E, Dranoff G, Fuchs CS, Ogino S.Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.J Pathol. 2010 Dec;222(
  20927778
• Baba Y, Nosho K, Shima K, Meyerhardt JA, Chan AT, Engelman JA, Cantley LC, Loda M, Giovannucci E, Fuchs CS, Ogino S.Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.Br J Cancer. 2010 S
  20808308
• Irahara N, Baba Y, Nosho K, Shima K, Yan L, Dias-Santagata D, Iafrate AJ, Fuchs CS, Haigis KM, Ogino S.NRAS mutations are rare in colorectal cancer.Diagn Mol Pathol. 2010 Sep;19(3):157-63.
  20736745
• Baba Y, Huttenhower C, Nosho K, Tanaka N, Shima K, Hazra A, Schernhammer ES, Hunter DJ, Giovannucci EL, Fuchs CS, Ogino S.Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.Mol Cancer. 2010;9:125.
  20507599
• Schernhammer ES, Giovannucci E, Kawasaki T, Rosner B, Fuchs C, Ogino S.Dietary Folate, Alcohol, and B Vitamins in Relation to LINE-1 Hypomethylation in Colon Cancer.Gut. 2010 Jun;59(6):794-9.
  19828464
• Baba Y, Nosho K, Shima K, Irahara N, Chan AT, Meyerhardt JA, Chung DC, Giovannucci EL, Fuchs CS, Ogino S.HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.Am J Pathol. 2010 May;176(5):2292-301.
  20363910
• Firestein R, Shima K, Nosho K, Irahara N, Baba Y, Bojarski E, Giovannucci EL, Hahn WC, Fuchs CS, Ogino S.CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.Int J Cancer. 2010
  19790197
• Ogino S, Stampfer M.Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology.Journal of the National Cancer Institute. 2010 Mar 17;102(6):365-7.
  20208016
• Hazra A, Fuchs CS, Kawasaki T, Kirkner GJ, Hunter DJ, Ogino S.Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.Cancer Causes Control. 2010 Mar;21(3):331-45.
  19936946
• Baba Y, Nosho K, Shima K, Goessling W, Chan AT, Ng K, Chan JA, Giovannucci EL, Fuchs CS, Ogino S.PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.Cancer Epidemiol Biom
  20200425
• Irahara N, Nosho K, Baba Y, Shima K, Lindeman NI, Hazra A, Schernhammer ES, Hunter DJ, Fuchs CS, Ogino S.Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells.J Mol Diagn. 2010 M
  20093385
• Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Mino-Kenudson M, Giovannucci EL, Meyerhardt JA, Fuchs CS.Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lympho
  19809407
• Meyerhardt JA, Giovannucci EL, Ogino S, Kirkner GJ, Chan AT, Willett W, Fuchs CS.Physical activity and male colorectal cancer survival.Arch Intern Med. 2009 Dec 14;169(22):2102-8.
  20008694
• Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Schaefer P, Whittom R, Hantel A, Benson AB, Goldberg RM, Bertagnolli MM, Fuchs CS, , , , .KRAS mutation in stage III colon cancer and clinical outcome following intergroup
  19934290
• Nosho K, Kure S, Irahara N, Shima K, Baba Y, Spiegelman D, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.Gastroenterology. 2009 Nov;1
  19686742
• Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS.Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node co
  19825961
• Kure S, Nosho K, Baba Y, Irahara N, Shima K, Ng K, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
  19789368
• Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Meyerhardt JA, Fuchs CS.Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.J Clin Oncol. 2009 Sep 20;27(27)
  19704056
• Monzon FA, Ogino S, Hammond ME, Halling KC, Bloom KJ, Nikiforova MN.The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer.Arch Pathol Lab Med. 2009 Oct;133(10):1600-6. Review.
  19792050
• Meyerhardt JA, Ogino S, Kirkner GJ, Chan AT, Wolpin B, Ng K, Nosho K, Shima K, Giovannucci EL, Loda M, Fuchs CS.Interaction of molecular markers and physical activity on mortality in patients with colon cancer.Clin Cancer Res. 2009 Sep 15;15(18):5931-6.
  19723652
• Ogino S, Nosho K, Shima K, Baba Y, Irahara N, Kirkner GJ, Hazra A, De Vivo I, Giovannucci EL, Meyerhardt JA, Fuchs CS.p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.Cancer Epidemiol Biomarkers Prev. 20
  19723919
• Worthley DL, Le Leu RK, Whitehall VL, Conlon M, Christophersen C, Belobrajdic D, Mallitt KA, Hu Y, Irahara N, Ogino S, Leggett BA, Young GP.A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation:
  19640954
• Chan AT, Ogino S, Fuchs CS.Aspirin use and survival after diagnosis of colorectal cancer.JAMA. 2009 Aug 12;302(6):649-58.
  19671906
• Ogino S, Nosho K, Baba Y, Kure S, Shima K, Irahara N, Toyoda S, Chen L, Kirkner GJ, Wolpin BM, Chan AT, Giovannucci EL, Fuchs CS.A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.Am J Gastroenterol. 2009 Aug;104(8):204
  19513025
• Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA.Prognostic and predictive value of common mutations f
  19603024
• Baba Y, Nosho K, Shima K, Freed E, Irahara N, Philips J, Meyerhardt JA, Hornick JL, Shivdasani RA, Fuchs CS, Ogino S.Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.Clin Cancer Res. 2009 Jul 15;15(14):4665-73.
  19584150
• Ogino S, Nosho K, Irahara N, Kure S, Shima K, Baba Y, Toyoda S, Chen L, Giovannucci EL, Meyerhardt JA, Fuchs CS.A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
  19549773
• Nosho K,Shima K,Irahara N,Kure S,Firestein R,Baba Y,Toyoda S,Chen L,Hazra A,Giovannucci EL,Fuchs CS,Ogino S.SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.Mod Pat
  19430421
• Sepulveda AR, Jones D, Ogino S, Samowitz W, Gulley ML, Edwards R, Levenson V, Pratt VM, Yang B, Nafa K, Yan L, Vitazka P.CpG methylation analysis--current status of clinical assays and potential applications in molecular diagnostics: a report of the Assoc
  19541921
• Ogino S, Shima K, Nosho K, Irahara N, Baba Y, Wolpin BM, Giovannucci EL, Meyerhardt JA, Fuchs CS.A cohort study of p27 localization in colon cancer, body mass index, and patient survival.Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
  19505918
• Nosho K,Shima K,Irahara N,Kure S,Baba Y,Kirkner GJ,Chen L,Gokhale S,Hazra A,Spiegelman D,Giovannucci EL,Jaenisch R,Fuchs CS,Ogino S.DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer.Clin Cancer Res. 2009 Jun 1;15(1
  19470733
• Baba Y,Nosho K,Shima K,Irahara N,Kure S,Toyoda S,Kirkner GJ,Goel A,Fuchs CS,Ogino S.Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.Neoplasia. 2009 May;11(5):418-25.
  19412426
• Ogino S,Nosho K,Kirkner GJ,Shima K,Irahara N,Kure S,Chan AT,Engelman JA,Kraft P,Cantley LC,Giovannucci EL,Fuchs CS.PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.J Clin Oncol. 2009 Mar 20;27(9):1477-
  19237633
• Ogino S,Shima K,Baba Y,Nosho K,Irahara N,Kure S,Chen L,Toyoda S,Kirkner GJ,Wang YL,Giovannucci EL,Fuchs CS.Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.Gastroenterolo
  19186181
• Nosho K,Shima K,Kure S,Irahara N,Baba Y,Chen L,Kirkner GJ,Fuchs CS,Ogino S.JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.Neoplasia. 2009 Jan;11(1):87-9
  19107235
• Ogino S,Kirkner GJ,Nosho K,Irahara N,Kure S,Shima K,Hazra A,Chan AT,Dehari R,Giovannucci EL,Fuchs CS.Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.Clin Cancer Res. 2008 Dec 15;14(24):8221-7.
  19088039
• Ogino S,Nosho K,Kirkner GJ,Kawasaki T,Chan AT,Schernhammer ES,Giovannucci EL,Fuchs CS.A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.Journal of the National Cancer Institute. 2008 Dec 3;100(23):1734-8.
  19033568
• Nosho K,Irahara N,Shima K,Kure S,Kirkner GJ,Schernhammer ES,Hazra A,Hunter DJ,Quackenbush J,Spiegelman D,Giovannucci EL,Fuchs CS,Ogino S.Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population
  19002263
• Nosho K, Kawasaki T, Chan AT, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S.Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.Histopathology. 2008 Nov;53(5):588-98.
  18983468
• Ogino S,Nosho K,Meyerhardt JA,Kirkner GJ,Chan AT,Kawasaki T,Giovannucci EL,Loda M,Fuchs CS.Cohort study of fatty acid synthase expression and patient survival in colon cancer.J Clin Oncol. 2008 Dec 10;26(35):5713-20.
  18955444
• Schernhammer ES,Giovannuccci E,Fuchs CS,Ogino S.A prospective study of dietary folate and vitamin B and colon cancer according to microsatellite instability and KRAS mutational status.Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2895-8.
  18843035
• Ogino S,Nosho K,Kirkner GJ,Kawasaki T,Meyerhardt JA,Loda M,Giovannucci EL,Fuchs CS.CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.Gut. 2009 Jan;58(1):90-6.
  18832519
• Firestein R,Bass AJ,Kim SY,Dunn IF,Silver SJ,Guney I,Freed E,Ligon AH,Vena N,Ogino S,Chheda MG,Tamayo P,Finn S,Shrestha Y,Boehm JS,Jain S,Bojarski E,Mermel C,Barretina J,Chan JA,Baselga J,Tabernero J,Root DE,Fuchs CS,Loda M,Shivdasani RA,Meyerson M,Hahn W
  18794900
• Samowitz WS,Ogino S.DNA methylation in breast and colorectal cancers.Mod Pathol. 2008 Aug;21(8):1054; author reply 1054-5.
  18654590
• Schernhammer ES,Ogino S,Fuchs CS.Folate and vitamin B6 intake and risk of colon cancer in relation to p53 expression.Gastroenterology. 2008 Sep;135(3):770-80.
  18619459
• Schernhammer ES, Ogino S, Fuchs CS.Folate and Vitamin B(6) Intake and Risk of Colon Cancer in Relation to p53 Expression.Gastroenterology..
• Nosho K,Kawasaki T,Ohnishi M,Suemoto Y,Kirkner GJ,Zepf D,Yan L,Longtine JA,Fuchs CS,Ogino S.PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.Neoplasia. 2008 Jun;10(6):534-41.
  18516290
• Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA.The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.PLoS ONE. 2008;3(4)
  18414679
• Ogino S,Kawasaki T,Nosho K,Ohnishi M,Suemoto Y,Kirkner GJ,Fuchs CS.LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.Int J Cancer. 2008 Jun 15;122(12):2767-73.
  18366060
• Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Glickman JN, Chan AT, Kirkner GJ, Mino-Kenudson M, Fuchs CS, Ogino S.Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serra
  18230181
• Kawasaki T, Ohnishi M, Nosho K, Suemoto Y, Kirkner GJ, Meyerhardt JA, Fuchs CS, Ogino S.CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at indivi
  18204436
• Ogino S, Goel A.Molecular classification and correlates in colorectal cancer.J Mol Diagn. 2008 Jan;10(1):13-27. Review.
  18165277
• Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S.IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.Neoplasia. 2007 Dec;9(12):1091-8.
  18084616
• Kawasaki T, Ohnishi M, Suemoto Y, Kirkner GJ, Liu Z, Yamamoto H, Loda M, Fuchs CS, Ogino S.WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.Mod Pathol.
  18084250
• Park do Y, Sakamoto H, Kirley SD, Ogino S, Kawasaki T, Kwon E, Mino-Kenudson M, Lauwers GY, Chung DC, Rueda BR, Zukerberg LR.The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.Am J Pathol
  17982127
• Ogino S, Kawasaki T, Kirkner GJ, Suemoto Y, Meyerhardt JA, Fuchs CS.Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.Gut. 2007 Nov;56(11):1564-71.
  17339237
• Ogino S, Hazra A, Tranah GJ, Kirkner GJ, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Meyerhardt JA, Hunter DJ, Fuchs CS.MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.Carcinogenesis.
  17621591
• Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Dehari R, Meyerhardt JA, Fuchs CS, Ogino S.Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.Neoplasia. 2007 Jul
  17710160
• Wang F, Wang L, Briggs C, Sicinska E, Gaston SM, Mamon H, Kulke MH, Zamponi R, Loda M, Maher E, Ogino S, Fuchs CS, Li J, Hader C, Makrigiorgos GM.DNA degradation test predicts success in whole-genome amplification from diverse clinical samples.J Mol Diagn
  17690213
• Meyerhardt JA, Clark JW, Supko JG, Eder JP, Ogino S, Stewart CF, D'Amato F, Dancey J, Enzinger PC, Zhu AX, Ryan DP, Earle CC, Mayer RJ, Michelini A, Kinsella K, Fuchs CS.Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients
  17216531
• Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS.Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.J Mol Diagn. 2007 Jul;9(3):305-14.
  17591929
• Gulley ML, Braziel RM, Halling KC, Hsi ED, Kant JA, Nikiforova MN, Nowak JA, Ogino S, Oliveira A, Polesky HF, Silverman L, Tubbs RR, Van Deerlin VM, Vance GH, Versalovic J,.Clinical laboratory reports in molecular pathology.Arch Pathol Lab Med. 2007 Jun;1
  17550311
• Chan AT, Ogino S, Fuchs CS.Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of COX-2.N Engl J Med. 2007 May 24;356(21):2131-2142.
  17522398
• Ogino S, Kawasaki T, Ogawa A, Kirkner GJ, Loda M, Fuchs CS.Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.Hum Pathol. 2007 Jun;38(6):842-9.
  17350669
• Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS.Evaluation of Markers for CpG Island Methylator Phenotype (CIMP) in Colorectal Cancer by a Large Population-Based Sample.J Mol Diagn. 2007 May 3.
  17478565
• Ogino S, Kawasaki T, Kirkner GJ, Ohnishi M, Fuchs CS.18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated positively with CpG island methylator phenotype-negative (CIMP-negative) and inversely with CIMP-low and CIMP-high.BMC
  17474983
• Ogino S, Meyerhardt JA, Kawasaki T, Clark JW, Ryan DP, Kulke MH, Enzinger PC, Wolpin BM, Loda M, Fuchs CS.CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.Virchows Ar
  17372756
• Ogino S, Kawasaki T, Ogawa A, Kirkner GJ, Loda M, Fuchs CS.TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.Hum Pathol. 2007 Apr;38(4):614-20.
  17270239
• Ogino S, Kawasaki T, Ogawa A, Kirkner GJ, Loda M, Fuchs CS.Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator
  17239930
• Ogino S, Wilson RB, Gold B, Flodman P.Bayesian Risk Assessment in Genetic Testing for Autosomal Dominant Disorders with Age-Dependent Penetrance.J Genet Couns. 2007 Feb;16(1):29-39.
  17295057
• Ogino S, Gulley ML, den Dunnen JT, Wilson RB.Standard Mutation Nomenclature in Molecular Diagnostics: Practical and Educational Challenges.J Mol Diagn. 2007 Feb;9(1):1-6.
  17251329
• Ogino S, Kawasaki T, Kirkner GJ, Yamaji T, Loda M, Fuchs CS.Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.Mod Pathol. 2007 Jan;20(1):15-22.
  17086168
• Ogino S, Kawasaki T, Kirkner G, Ogawa A, Dorfman I, Loda M, Fuchs C.Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.J Pathol. 2006 Oct;210(2):147-
  16850502
• Priolo C, Tang D, Brahamandan M, Benassi B, Sicinska E, Ogino S, Farsetti A, Porrello A, Finn S, Zimmermann J, Febbo P, Loda M.The Isopeptidase USP2a Protects Human Prostate Cancer from Apoptosis.Cancer Res. 2006 Sep 1;66(17):8625-32.
  16951176
• Ogino S, Odze RD, Kawasaki T, Brahmandam M, Kirkner GJ, Laird PW, Loda M, Fuchs CS.Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.Am J Surg Pathol. 2006 Sep;3
  16931963
• Ogino S, Brahmandam M, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS.Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.Mod Pathol. 2006 Aug;19(8):1083-90.
  16699497
• Ogino S, Brahmandam M, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS.Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer.Neoplasia. 200
  16820091
• Meyerhardt JA, Heseltine D, Ogino S, Clark JW, Enzinger PC, Ryan DP, Earle CC, Zhu AX, Fuchs CS.Efficacy of cetuximab after treatment with oral epidermal growth factor receptor tyrosine kinase inhibitor-based chemotherapy in metastatic colorectal cancer.C
  16796793
• Ogino S, Cantor M, Kawasaki T, Brahmandam M, Kirkner G, Weisenberger DJ, Campan M, Laird PW, Loda M, Fuchs CS.CpG island methylator phenotype (CIMP) of colorectal cancer is best characterized by quantitative DNA methylation analysis and prospective cohort
  16407376
• Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, Makrigiorgos GM, Weisenberger DJ, Laird PW, Loda M, Fuchs CS.Precision and Performance Characteristics of Bisulfite Conversion and Real-Time PCR (MethyLight) for Quantitative DNA Methy
  16645207
• Ogino S, Brahmandam M, Cantor M, Namgyal C, Kawasaki T, Kirkner G, Meyerhardt JA, Loda M, Fuchs CS.Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.Mod Pathol. 2006 Jan;19
  16118624
• Giovannucci E, Ogino S.DNA methylation, field effects, and colorectal cancer.J Natl Cancer Inst. 2005 Sep 21;97(18):1317-9.
  16174847
• Ogino S, Meyerhardt JA, Cantor M, Brahmandam M, Clark JW, Namgyal C, Kawasaki T, Kinsella K, Michelini AL, Enzinger PC, Kulke MH, Ryan DP, Loda M, Fuchs CS.Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advance
  16166444
• Ogino S, Kawasaki T, Brahmandam M, Yan L, Cantor M, Namgyal C, Mino-Kenudson M, Lauwers GY, Loda M, Fuchs CS.Sensitive sequencing method for KRAS mutation detection by Pyrosequencing.J Mol Diagn. 2005 Aug;7(3):413-21.
  16049314
• Ogino S, Flodman P, Wilson RB, Gold B, Grody WW.Risk calculations for cystic fibrosis in neonatal screening by immunoreactive trypsinogen and CFTR mutation tests.Genet Med. 2005 May-Jun;7(5):317-27.
  15915083
• Ogino S, Wilson RB, Gold B.New insights on the evolution of the SMN1 and SMN2 region: simulation and meta-analysis for allele and haplotype frequency calculations.Eur J Hum Genet. 2004 Dec;12(12):1015-23.
  15470363
• Khurana JS, Ogino S, Shen T, Parekh H, Scherbel U, Delong W, Feldman MD, Zhang PJ, Wolfe HJ, Alman BA.Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions.Arch Pathol Lab Med. 2004 11;128(11):1267-1269.
  15506826
• Ogino S, Wilson RB, Gold B, Hawley P, Grody WW.Bayesian analysis for cystic fibrosis risks in prenatal and carrier screening.Genet Med. 2004 Sep-Oct;6(5):439-49.
  15371910
• Ogino S, Wilson RB, Grody WW.Bayesian risk assessment for autosomal recessive diseases: fetal echogenic bowel with one or no detectable CFTR mutation.J Med Genet. 2004 May;41(5):e70.
  15121798
• Ogino S, Wilson RB.Importance of standard nomenclature for SMN1 small intragenic ("subtle") mutations.Hum Mutat. 2004 Apr;23(4):392-3.
  15024734
• Xu R, Ogino S, Lip V, Fang H, Wu BL.Comparison of PCR-RFLP with allele-specific PCR in genetic testing for spinal muscular atrophy.Genet Test. 2003 Winter;7(4):277-81.
  15000803
• Ogino S, Wilson RB.Bayesian analysis and risk assessment in genetic counseling and testing.J Mol Diagn. 2004 Feb;6(1):1-9.
  14736820
• Ogino S, Wilson RB.Spinal muscular atrophy: molecular genetics and diagnostics.Expert Rev Mol Diagn. 2004 Jan;4(1):15-29.
  14711346
• Ogino S, Gao S, Leonard DG, Paessler M, Wilson RB.Inverse correlation between SMN1 and SMN2 copy numbers: evidence for gene conversion from SMN2 to SMN1.Eur J Hum Genet. 2003 Sep;11(9):723.
  12939662
• Ogino S, Wilson RB.The practice of science at its best.Fertil Steril. 2003 Jul;80(1):228-9; author reply 229.
  12849835
• Ogino S, Gao S, Leonard DG, Paessler M, Wilson RB.Inverse correlation between SMN1 and SMN2 copy numbers: evidence for gene conversion from SMN2 to SMN1.Eur J Hum Genet. 2003 Mar;11(3):275-7.
  12673282
• Ogino S, Wilson RB.Genotype and haplotype distributions of MTHFR677C>T and 1298A>C single nucleotide polymorphisms: a meta-analysis.J Hum Genet. 2003;48(1):1-7.
  12560871
• Ogino S, Wilson RB.Genetic testing and risk assessment for spinal muscular atrophy (SMA).Hum Genet. 2002 Dec;111(6):477-500.
  12436240
• Ogino S, Wilson RB.Quantification of PCR bias caused by a single nucleotide polymorphism in SMN gene dosage analysis.J Mol Diagn. 2002 Nov;4(4):185-90.
  12411585
• Ogino S, Franks TJ, Yong M, Koss MN.Extensive squamous metaplasia with cytologic atypia in diffuse alveolar damage mimicking squamous cell carcinoma: a report of 2 cases.Hum Pathol. 2002 Oct;33(10):1052-4.
  12395381
• Ogino S, Leonard DG, Rennert H, Ewens WJ, Wilson RB.Genetic risk assessment in carrier testing for spinal muscular atrophy.Am J Med Genet. 2002 Jul 15;110(4):301-7.
  12116201
• Ogino S, Wilson RB.SMN dosage analysis and risk assessment for spinal muscular atrophy.Am J Hum Genet. 2002 Jun;70(6):1596-8; author reply 1598.
  11992267
• Ogino S, Van Deerlin VM, Wilson RB.Comment on SMN2 deletion in childhood-onset spinal muscular atrophy.Am J Med Genet. 2002 May 1;109(3):243-4; author reply 245.
  11977189
• Ogino S, Leonard DG, Rennert H, Wilson RB.Spinal muscular atrophy genetic testing experience at an academic medical center.J Mol Diagn. 2002 Feb;4(1):53-8.
  11826188
• Ogino S, Leonard DG, Rennert H, Gao S, Wilson RB.Heteroduplex formation in SMN gene dosage analysis.J Mol Diagn. 2001 Nov;3(4):150-7.
  11687598
• Ogino S.A method to compensate for different amplification efficiencies.J Mol Diagn. 2001 Nov;3(4):189-90.
  11687603
• Ogino S, Kubo S, Abdul-Karim FW, Cohen ML.Comparative immunohistochemical study of insulin-like growth factor II and insulin-like growth factor receptor type 1 in pediatric brain tumors.Pediatr Dev Pathol. 2001 Jan-Feb;4(1):23-31.
  11200487
• Ogino S, Redline RW.Villous capillary lesions of the placenta: distinctions between chorangioma, chorangiomatosis, and chorangiosis.Hum Pathol. 2000 Aug;31(8):945-54.
  10987255
• Ogino S, Franks TJ, Deubner H, Koss MN.Thymohemangiolipoma, a rare histologic variant of thymolipoma: a case report and review of the literature.Ann Diagn Pathol. 2000 Aug;4(4):236-9.
  10982301
• Ogino S, Ro TY, Redline RW.Malignant rhabdoid tumor: A phenotype? An entity?--A controversy revisited.Adv Anat Pathol. 2000 May;7(3):181-90.
  10809224
• Ogino S, al-Kaisi N, Abdul-Karim FW.Cytopathology of oncocytic carcinoid tumor of the lung mimicking granular cell tumor. A case report.Acta Cytol. 2000 Mar-Apr;44(2):247-50.
  10740615
• Kubo S, Ogino S, Fukushima T, Olson PR, Kida M, Maruno M, Yoshimine T, Hyakawa T.Immunohistochemical study of insulin-like growth factor II (IGF-II) and insulin-like growth factor binding protein-2 (IGFBP-2) in choroid plexus papilloma.Neurol Res. 1999 Ju
  10406004
• Ogino S, Cohen ML, Abdul-Karim FW.Atypical teratoid/rhabdoid tumor of the CNS: cytopathology and immunohistochemistry of insulin-like growth factor-II, insulin-like growth factor receptor type 1, cathepsin D, and Ki-67.Mod Pathol. 1999 Apr;12(4):379-85.
  10229502
• Kubo S, Ogino S, Fukushima T, Maruno M, Yoshimine T, Hasegawa H.Immunocytochemical detection of insulin-like growth factor II (IGF-II) in choroid plexus papilloma: a possible marker for differential diagnosis.Clin Neuropathol. 1999 Mar-Apr;18(2):74-9.
  10192701
• Ing EB, Kennerdell JS, Olson PR, Ogino S, Rothfus WE.Solitary fibrous tumor of the orbit.Ophthal Plast Reconstr Surg. 1998 Jan;14(1):57-61.
  9513245