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Karen K. Ballen, MD

Publications

  • Brunner AM, Blonquist TM, Sadrzadeh H, Perry AM, Attar EC, Amrein PC, Ballen KK, Chen YB, Neuberg DS, Fathi AT.Population-based disparities in survival among patients with core-binding factor acute myeloid leukemia: A SEER database analysis.Leuk Res. 2014 Jul;38(7):773-80.
    24793731
  • Ballen KK.The Optimal Donor Source for Acute Myeloid Leukemia: Do We Know the Answer?.Biol Blood Marrow Transplant. 2014 Apr 12.
    24727331
  • Wood WA, Lee SJ, Brazauskas R, Wang Z, Aljurf MD, Ballen KK, Buchbinder DK, Dehn J, Freytes CO, Lazarus HM, Lemaistre CF, Mehta P, Szwajcer D, Joffe S, Majhail NS.Survival Improvements in Adolescents and Young Adults after Myeloablative Allogeneic Transplantation for Acute Lymphoblastic Leukemia.Biol Blood Marrow Transplant. 2014 Mar 7.
    24607554
  • Yeh AC, Brunner AM, Spitzer TR, Chen YB, Coughlin E, McAfee S, Ballen K, Attar E, Caron M, Preffer FI, Yeap BY, Dey BR.Phase I study of urate oxidase in the reduction of acute graft-versus-host disease after myeloablative allogeneic stem cell transplantation.Biol Blood Marrow Transplant. 2014 May;20(5):730-4.
    24530972
  • Omer AK, Kim HT, Yalamarti B, McAfee SL, Dey BR, Ballen KK, Attar E, Chen YB, Spitzer TR.Engraftment syndrome after allogeneic hematopoietic cell transplantation in adults.Am J Hematol. 2014 Mar 25.
    24668776
  • Ballen KK.ATG for cord blood transplant: yes or no?.Blood. 2014 Jan 2;123(1):7-8.
    24385495
  • Gupta V, Malone AK, Hari PN, Ahn KW, Hu ZH, Gale RP, Ballen KK, Hamadani M, Olavarria E, Gerds AT, Waller EK, Costa LJ, Antin JH, Kamble RT, van Besien KM, Savani BN, Schouten HC, Szer J, Cahn JY, de Lima MJ, Wirk B, Aljurf MD, Popat U, Bejanyan N, Litzow MR, Norkin M, Lewis ID, Hale GA, Woolfrey AE, Miller AM, Ustun C, Jagasia MH, Lill M, Maziarz RT, Cortes J, Kalaycio ME, Saber W.Reduced-intensity hematopoietic cell transplantation for patients with primary myelofibrosis: a cohort analysis from the center for international blood and marrow transplant research.Biol Blood Marrow Transplant. 2014 Jan;20(1):89-97.
    24161923
  • Brunner AM, Kim HT, Coughlin E, Alyea EP, Armand P, Ballen KK, Cutler C, Dey BR, Glotzbecker B, Koreth J, McAfee SL, Spitzer TR, Soiffer RJ, Antin JH, Ho VT, Chen YB.Outcomes in patients age 70 or older undergoing allogeneic hematopoietic stem cell transplantation for hematologic malignancies.Biol Blood Marrow Transplant. 2013 Sep;19(9):1374-80.
    23791626
  • Bhatt AS, Freeman SS, Herrera AF, Pedamallu CS, Gevers D, Duke F, Jung J, Michaud M, Walker BJ, Young S, Earl AM, Kostic AD, Ojesina AI, Hasserjian R, Ballen KK, Chen YB, Hobbs G, Antin JH, Soiffer RJ, Baden LR, Garrett WS, Hornick JL, Marty FM, Meyerson M.Sequence-based discovery of Bradyrhizobium enterica in cord colitis syndrome.N Engl J Med. 2013 Aug 8;369(6):517-28.
    23924002
  • Attar EC, Amrein PC, Fraser JW, Fathi AT, McAfee S, Wadleigh M, Deangelo DJ, Steensma DP, Stone RM, Foster J, Neuberg D, Ballen KK.Phase I dose escalation study of bortezomib in combination with lenalidomide in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).Leuk Res. 2013 Sep;37(9):1016-20.
    23773898
  • Omer AK, Ziakas PD, Anagnostou T, Coughlin E, Kourkoumpetis T, McAfee SL, Dey BR, Attar E, Chen YB, Spitzer TR, Mylonakis E, Ballen KK.Risk factors for invasive fungal disease after allogeneic hematopoietic stem cell transplantation: a single center experience.Biol Blood Marrow Transplant. 2013 Aug;19(8):1190-6.
    23747459
  • Delaney M, Ballen KK.Umbilical Cord Blood Transplantation: Review of Factors Affecting the Hospitalized Patient.J Intensive Care Med. 2013 May 12.
    23753249
  • Brunner AM, Sadrzadeh H, Feng Y, Drapkin BJ, Ballen KK, Attar EC, Amrein PC, McAfee SL, Chen YB, Scd DS, Fathi AT.Association between baseline body mass index (BMI) and overall survival among patients over age 60 with acute myeloid leukemia (AML).Am J Hematol. 2013 Apr 26.
    23619915
  • Chen YB, Coughlin E, Kennedy KF, Alyea EP, Armand P, Attar EC, Ballen KK, Cutler C, Dey BR, Koreth J, McAfee SL, Spitzer TR, Antin JH, Soiffer RJ, Ho VT.Busulfan Dose Intensity and Outcomes in Reduced-Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for Myelodysplastic Syndrome or Acute Myeloid Leukemia.Biol Blood Marrow Transplant. 2013 Apr 2.
    23562738
  • Ballen KK, Barker JN.Has umbilical cord blood transplantation for AML become mainstream?.Curr Opin Hematol. 2013 Mar;20(2):144-9.
    23314845
  • Cutler C, Ballen KK.Improving outcomes in umbilical cord blood transplantation: State of the art.Blood Rev. 2012 Nov;26(6):241-6.
    22958984
  • Fathi AT, Sadrzadeh H, Borger DR, Ballen KK, Amrein PC, Attar EC, Foster J, Burke M, Lopez HU, Matulis CR, Edmonds KM, Iafrate AJ, Straley KS, Yen KE, Agresta S, Schenkein DP, Hill C, Emadi A, Neuberg DS, Stone RM, Chen YB.Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response.Blood. 2012 Oct 16.
    23074281
  • Fathi AT, Preffer FI, Sadrzadeh H, Ballen KK, Amrein PC, Attar EC, McAfee SL, Dillon L, Chen YB, Hasserjian RP.CD30 expression in acute myeloid leukemia is associated with FLT3-internal tandem duplication mutation and leukocytosis.Leuk Lymphoma. 2012 Sep 28.
    22966913
  • Keating A, da Silva GT, Perez WS, Gupta V, Cutler CS, Ballen KK, Cairo MS, Camitta BM, Champlin RE, Gajewski JL, Lazarus HM, Lill M, Marks DI, Nabhan C, Schiller GJ, Socie' G, Szer J, Tallman MS, Weisdorf DJ.Autologous blood cell transplantation versus HLA-identical siblingtransplantation for acute myeloid leukemia in first complete remission:a registry study from the Center for International Blood and MarrowTransplantation Research.Haematologica. 2012 Sep 14.
    22983587
  • Spitzer TR, Dey BR, Chen YB, Attar E, Ballen KK.The expanding frontier of hematopoietic cell transplantation.Cytometry. Part B, Clinical Cytometry. 2012 Sep;82(5):271-9.
    22865649
  • Brunstein CG, Eapen M, Ahn KW, Appelbaum FR, Ballen KK, Champlin RE, Cutler C, Kan F, Laughlin MJ, Soiffer RJ, Weisdorf DJ, Woolfrey A, Wagner JE.Reduced-intensity conditioning transplantation in acute leukemia: the effect of source of unrelated donor stem cells on outcomes.Blood. 2012 Jun 7;119(23):5591-8.
    22496153
  • Amrein PC, Attar EC, Takvorian RW, Hochberg EP, Ballen KK, Leahy KM, Fisher DE, Lacasce AS, Jacobsen ED, Armand P, Hasserjian RP, Werner L, Neuberg DS, Brown JR.Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia.Clin Cancer Res. 2011 Mar 14.
    21402714
  • Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB.Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease.Transplantation. 2011 Mar 27;91(6):672-6.
    21217460
  • Horan JT, Logan BR, Agovi-Johnson MA, Lazarus HM, Bacigalupo AA, Ballen KK, Bredeson CN, Carabasi MH, Gupta V, Hale GA, Khoury HJ, Juckett MB, Litzow MR, Martino R, McCarthy PL, Smith FO, Rizzo JD, Pasquini MC.Reducing the risk for transplantation-related mortality after allogeneic hematopoietic cell transplantation: how much progress has been made?.J Clin Oncol. 2011 Mar 1;29(7):805-13.
    21220593
  • Dey BR, Chung SS, Spitzer TR, Zheng H, Macgillivray TE, Seldin DC, McAfee S, Ballen K, Attar E, Wang T, Shin J, Newton-Cheh C, Moore S, Sanchorawala V, Skinner M, Madsen JC, Semigran MJ.Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.Transplantation. 2010 Oct 27;90(8):905-11.
    20733534
  • Delaney M, Ballen KK.The role of HLA in umbilical cord blood transplantation.Best Pract Res Clin Haematol. 2010 Jun;23(2):179-87.
    20837329
  • Barker CC, Agovi MA, Logan B, Lazarus HM, Ballen KK, Gupta V, Hale GA, Frangoul H, Ho V, Rizzo JD, Pasquini MC, .Childhood Obesity and Outcomes after Bone Marrow Transplantation for Patients with Severe Aplastic Anemia.Biol Blood Marrow Transplant. 2010 Sep 1.
    20817111
  • Cutler C, Stevenson K, Kim HT, Brown J, McDonough S, Herrera M, Reynolds C, Liney D, Kao G, Ho V, Armand P, Koreth J, Alyea E, Dey BR, Attar E, Spitzer T, Boussiotis VA, Ritz J, Soiffer R, Antin JH, Ballen K.Double umbilical cord blood transplantation with reduced intensity conditioning and sirolimus-based GVHD prophylaxis.Bone Marrow Transplant. 2010 Aug 9.
    20697368
  • Ballen KK, Cutler C, Yeap BY, McAfee SL, Dey BR, Attar EC, Chen YB, Haspel RL, Liney D, Koreth J, Ho V, Alyea EP, Soiffer RJ, Spitzer TR, Antin JH.Donor Derived Second Hematologic Malignancies after Cord Blood Transplantation.Biol Blood Marrow Transplant. 2010 Jul;16(7):1025-31.
    20178854
  • Schriber J, Agovi MA, Ho V, Ballen KK, Bacigalupo A, Lazarus HM, Bredeson CN, Gupta V, Maziarz RT, Hale GA, Litzow MR, Logan B, Bornhauser M, Giller RH, Isola L, Marks DI, Rizzo JD, Pasquini MC.Second unrelated donor hematopoietic cell transplantation for primary graft failure.Biol Blood Marrow Transplant. 2010 Aug;16(8):1099-106.
    20172038
  • Brown JA, Stevenson K, Kim HT, Cutler C, Ballen K, McDonough S, Reynolds C, Herrera M, Liney D, Ho V, Kao G, Armand P, Koreth J, Alyea E, McAfee S, Attar E, Dey B, Spitzer T, Soiffer R, Ritz J, Antin JH, Boussiotis VA.Clearance of CMV viremia and survival after double umbilical cord blood transplantation in adults depends on reconstitution of thymopoiesis.Blood. 2010 May 20;115(20):4111-9.
    20107229
  • Ballen KK, Shrestha S, Sobocinski KA, Zhang MJ, Bashey A, Bolwell BJ, Cervantes F, Devine SM, Gale RP, Gupta V, Hahn TE, Hogan WJ, Kröger N, Litzow MR, Marks DI, Maziarz RT, McCarthy PL, Schiller G, Schouten HC, Roy V, Wiernik PH, Horowitz MM, Giralt SA, Arora M.Outcome of transplantation for myelofibrosis.Biol Blood Marrow Transplant. 2010 Mar;16(3):358-67.
    19879949
  • Baker KS, Davies SM, Majhail NS, Hassebroek A, Klein JP, Ballen KK, Bigelow CL, Frangoul HA, Hardy CL, Bredeson C, Dehn J, Friedman D, Hahn T, Hale G, Lazarus HM, LeMaistre CF, Loberiza F, Maharaj D, McCarthy P, Setterholm M, Spellman S, Trigg M, Maziarz RT, Switzer G, Lee SJ, Rizzo JD.Race and socioeconomic status influence outcomes of unrelated donor hematopoietic cell transplantation.Biol Blood Marrow Transplant. 2009 Dec;15(12):1543-54.
    19896078
  • Ulrickson M, Aldridge J, Kim HT, Hochberg EP, Hammerman P, Dube C, Attar E, Ballen KK, Dey BR, McAfee SL, Spitzer TR, Chen YB.Busulfan and cyclophosphamide (Bu/Cy) as a preparative regimen for autologous stem cell transplantation in patients with non-Hodgkin lymphoma: a single-institution experience.Biol Blood Marrow Transplant. 2009 Nov;15(11):1447-54.
    19822305
  • Delaney M,Cutler CS,Haspel RL,Yeap BY,McAfee SL,Dey BR,Attar E,Kao G,Alyea EP,Koreth J,Ho VT,Saidman S,Liney D,Sese D,Soiffer RJ,Spitzer TR,Antin JH,Ballen KK.High-resolution HLA matching in double-umbilical-cord-blood reduced-intensity transplantation in adults.Transfusion. 2009 May;49(5):995-1002.
    19159415
  • Yusuf RZ, Dey B, Yeap BY, McAfee S, Attar E, Sepe PS, Dube C, Spitzer TR, Ballen KK.Autologous SCT with a dose-reduced BU and CY regimen in older patients with non-Hodgkin's lymphoma.Bone Marrow Transplant. 2009 Jan;43(1):37-42.
    18794868
  • Ting DT, Spitzer TR, Chaudhary A, Muzikansky A, Colby C, Power K, McAfee S, Ballen K, Attar E, Saidman SL, Preffer F, Sykes M, Dey BR.Clinical outcomes of late rather than early full-donor chimerism in patients with advanced lymphomas receiving nonmyeloablative allogeneic hematopoietic SCT.Bone Marrow Transplant. 2008 Sep;42(5):329-35.
    18587439
  • Karanes C,Nelson GO,Chitphakdithai P,Agura E,Ballen KK,Bolan CD,Porter DL,Uberti JP,King RJ,Confer DL.Twenty years of unrelated donor hematopoietic cell transplantation for adult recipients facilitated by the National Marrow Donor Program.Biol Blood Marrow Transplant. 2008 Sep;14(9 Suppl):8-15. Review.
    18721775
  • Ballen KK,King RJ,Chitphakdithai P,Bolan CD Jr,Agura E,Hartzman RJ,Kernan NA.The national marrow donor program 20 years of unrelated donor hematopoietic cell transplantation.Biol Blood Marrow Transplant. 2008 Sep;14(9 Suppl):2-7.
    18721774
  • Haspel RL, Kao G, Yeap BY, Cutler C, Soiffer RJ, Alyea EP, Ho VT, Koreth J, Dey BR, McAfee SL, Attar EC, Spitzer T, Antin JH, Ballen KK.Preinfusion variables predict the predominant unit in the setting of reduced-intensity double cord blood transplantation.Bone Marrow Transplant. 2008 Mar;41(6):523-9.
    18037942
  • Attar EC, De Angelo DJ, Supko JG, D'Amato F, Zahrieh D, Sirulnik A, Wadleigh M, Ballen KK, McAfee S, Miller KB, Levine J, Galinsky I, Trehu EG, Schenkein D, Neuberg D, Stone RM, Amrein PC.Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia.Clin Cancer Res. 2008 Mar 1;14(5):1446-54.
    18316568
  • Shaffer J, Villard J, Means TK, Alexander S, Dombkowski D, Dey BR, McAfee S, Ballen KK, Saidman S, Preffer FI, Sachs DH, Spitzer TR, Sykes M.Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine.Exp Hematol. 2007 Jul;35(7):1140-52.
    17588483
  • Ballen KK, Shpall EJ, Avigan D, Yeap BY, Fisher DC, McDermott K, Dey BR, Attar E, McAfee S, Konopleva M, Antin JH, Spitzer TR.Phase I trial of parathyroid hormone to facilitate stem cell mobilization.Biol Blood Marrow Transplant. 2007 Jul;13(7):838-43.
    17580262
  • Giralt S, Logan B, Rizzo D, Zhang MJ, Ballen K, Emmanouilides C, Nath R, Parker P, Porter D, Sandmaier B, Waller EK, Barker J, Pavletic S, Weisdorf D.Reduced-intensity conditioning for unrelated donor progenitor cell transplantation: long-term follow-up of the first 285 reported to the national marrow donor program.Biol Blood Marrow Transplant. 2007 Jul;13(7):844-52.
    17580263
  • Dey BR, Shaffer J, Yee AJ, McAfee S, Caron M, Power K, Ting DT, Colby C, Preffer F, Ballen K, Attar E, Saidman S, Tarbell N, Sachs D, Sykes M, Spitzer TR.Comparison of outcomes after transplantation of peripheral blood stem cells versus bone marrow following an identical nonmyeloablative conditioning regimen.Bone Marrow Transplant. 2007 Jul;40(1):19-27.
    17468773
  • Ballen K.Targeting the stem cell niche: squeezing blood from bones.Bone Marrow Transplant. 2007 Jun;39(11):655-60. Review.
    17401397
  • Haspel RL, Ballen KK.Double cord blood transplants: filling a niche?.Stem Cell Rev. 2006;2(2):81-6. Review.
    17237545
  • Ballen KK, Spitzer TR, Yeap BY, McAfee S, Dey BR, Attar E, Haspel R, Kao G, Liney D, Alyea E, Lee S, Cutler C, Ho V, Soiffer R, Antin JH.Double unrelated reduced-intensity umbilical cord blood transplantation in adults.Biol Blood Marrow Transplant. 2007 Jan;13(1):82-9.
    17222756
  • Anagnostopoulos A, Hari PN, Pérez WS, Ballen K, Bashey A, Bredeson CN, Freytes CO, Gale RP, Gertz MA, Gibson J, Goldschmidt H, Lazarus HM, McCarthy PL, Reece DE, Vesole DH, Giralt SA.Autologous or Allogeneic Stem Cell Transplantation in Patients with Waldenstrom's Macroglobulinemia.Biol Blood Marrow Transplant. 2006 Aug;12(8):845-54.
    16864055
  • Gold J, Valinski HM, Hanks AN, Ballen KK, Hsieh CC, Becker PS.Adhesion receptor expression by CD34+ cells from peripheral blood or bone marrow grafts: correlation with time to engraftment.Exp Hematol. 2006 May;34(5):680-7.
    16647574
  • Ballen KK, Colvin G, Dey BR, Porter D, Westervelt P, Spitzer TR, Quesenberry PJ.Cellular immune therapy for refractory cancers: novel therapeutic strategies.Exp Hematol. 2005 Dec;33(12):1427-35.
    16338484
  • Pavletic SZ, Khouri IF, Haagenson M, King RJ, Bierman PJ, Bishop MR, Carston M, Giralt S, Molina A, Copelan EA, Ringdén O, Roy V, Ballen K, Adkins DR, McCarthy P, Weisdorf D, Montserrat E, Anasetti C.Unrelated donor marrow transplantation for B-cell chronic lymphocytic leukemia after using myeloablative conditioning: results from the Center for International Blood and Marrow Transplant research.J Clin Oncol. 2005 Aug 20;23(24):5788-94.
    16043827
  • Ballen KK, King R, Carston M, Kollman C, Nelson G, Lim S, Reece D, Giralt S, Vesole DH.Outcome of unrelated transplants in patients with multiple myeloma.Bone Marrow Transplant. 2005 Apr;35(7):675-81.
    15723085
  • Ballen KK.New trends in umbilical cord blood transplantation.Blood. 2005 May 15;105(10):3786-92.
    15677563
  • Ballen KK, Hasserjian RP.Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 2-2005. A 39-year-old woman with headache, stiff neck, and photophobia.N Engl J Med. 2005 Jan 20;352(3):274-83.
    15659728
  • Ballen KK, Becker PS, Yeap BY, Matthews B, Henry DH, Ford PA.Autologous stem-cell transplantation can be performed safely without the use of blood-product support.J Clin Oncol. 2004 Oct 15;22(20):4087-94.
    15353543
  • Ballen KK, Kurtzberg J, Lane TA, Lindgren BR, Miller JP, Nagan D, Newman B, Rupp N, Haley NR.Racial diversity with high nucleated cell counts and CD34 counts achieved in a national network of cord blood banks.Biol Blood Marrow Transplant. 2004 Apr;10(4):269-75.
    15077225