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Ruth M. Ruprecht, MD, PhD


  • Chenine AL, Siddappa NB, Kramer VG, Sciaranghella G, Rasmussen RA, Lee SJ, Santosuosso M, Poznansky MC, Velu V, Amara RR, Souder C, Anderson DC, Villinger F, Else JG, Novembre FJ, Strobert E, O'Neil SP, Evan Secor W, Ruprecht RM.Relative Transmissibility of an R5 Clade C Simian-Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV-1 Transmission in Humans via Different Routes.J Infect Dis. 2010 Apr 15;201(8):1155-63.
  • Ho O, Larsen K, Polacino P, Li Y, Anderson D, Song R, Ruprecht RM, Hu SL.Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus.Retrovirology. 2009;6:65.
  • Van Rhijn I,Young DC,De Jong A,Vazquez J,Cheng TY,Talekar R,Barral D,Leon L,Brenner MB,Katz JT,Riese R,Ruprecht RM,O'Connor PB,Costello CE,Porcelli SA,Briken V,Moody DB.CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids.J Exp Med. 2009 Jun 8;206(6):1409-22.
  • Mirshahidi S, Kramer VG, Whitney JB, Essono S, Lee S, Dranoff G, Anderson KS, Ruprecht RM .Overlapping synthetic peptides encoding TPD52 as breast cancer vaccine in mice: prolonged survival.Vaccine. 3-13-2009;27(12):1825-33.
  • Ruprecht RM.Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: experimental approaches.Methods Mol Biol. 2009;525:559-66, xiv.
  • Humbert M,Rasmussen RA,Ong H,Kaiser FM,Hu SL,Ruprecht RM.Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing.PLoS ONE. 2008;3(12):e3937.
  • Siddappa NB,Song R,Kramer VG,Chenine AL,Velu V,Ong H,Rasmussen RA,Grisson RD,Wood C,Zhang H,Kankasa C,Amara RR,Else JG,Novembre FJ,Montefiori DC,Ruprecht RM.Neutralization-sensitive R5-tropic simian-human immunodeficiency virus SHIV-2873Nip, which carries env isolated from an infant with a recent HIV clade C infection.J Virol. 2009 Feb;83(3):1422-32.
  • Humbert M,Rasmussen RA,Song R,Ong H,Sharma P,Chenine AL,Kramer VG,Siddappa NB,Xu W,Else JG,Novembre FJ,Strobert E,O'Neil SP,Ruprecht RM.SHIV-1157i and passaged progeny viruses encoding R5 HIV-1 clade C env cause AIDS in rhesus monkeys.Retrovirology. 2008;5:94.
  • Chenine AL,Shai-Kobiler E,Steele LN,Ong H,Augostini P,Song R,Lee SJ,Autissier P,Ruprecht RM,Secor WE.Acute Schistosoma mansoni Infection Increases Susceptibility to Systemic SHIV Clade C Infection in Rhesus Macaques after Mucosal Virus Exposure.PLoS Negl Trop Dis. 2008;2(7):e265.
  • Polonis VR, Brown BK, Borges AR, Zolla-Pazner S, Dimitrov DS, Zhang MY, Barnett SW, Ruprecht RM, Scarlatti G, Fenyo EM, Montefiori DC, McCutchan FE, Michael NL.Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination.Virology. 2008 Jun 5;375(2):315-20. Review.
  • Zhang MY,Vu BK,Choudhary A,Lu H,Humbert M,Ong H,Alam M,Ruprecht RM,Quinnan G,Jiang S,Montefiori DC,Mascola JR,Broder CC,Haynes BF,Dimitrov DS.Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.J Virol. 2008 Jul;82(14):6869-79.
  • Kramer VG, Siddappa NB, Ruprecht RM.Passive immunization as tool to identify protective HIV-1 Env epitopes.Curr HIV Res. 2007 Nov;5(6):642-55. Review.
  • Jiang S, Rasmussen RA, Nolan KM, Frankel FR, Lieberman J, McClure HM, Williams KM, Babu US, Raybourne RB, Strobert E, Ruprecht RM.Live attenuated Listeria monocytogenes expressing HIV Gag: immunogenicity in rhesus monkeys.Vaccine. 2007 Oct 16;25(42):7470-9.
  • Gruber A, Chalmers AS, Rasmussen RA, Ong H, Popov S, Andersen J, Hu SL, Ruprecht RM.Dendritic cell-based vaccine strategy against human immunodeficiency virus clade C: skewing the immune response toward a helper T cell type 2 profile.Viral Immunol. 2007 Spring;20(1):160-9.
  • Ayash-Rashkovsky M, Chenine AL, Steele LN, Lee SJ, Song R, Ong H, Rasmussen RA, Hofmann-Lehmann R, Else JG, Augostini P, McClure HM, Secor WE, Ruprecht RM.Coinfection with Schistosoma mansoni reactivates viremia in rhesus macaques with chronic simian-human immunodeficiency virus clade C infection.Infect Immun. 2007 Apr;75(4):1751-6.
  • Ferrantelli F, Buckley KA, Rasmussen RA, Chalmers A, Wang T, Li PL, Williams AL, Hofmann-Lehmann R, Montefiori DC, Cavacini LA, Katinger H, Stiegler G, Anderson DC, McClure HM, Ruprecht RM.Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques.Virology. 2007 Feb 5;358(1):69-78.
  • Jiang S, Song R, Popov S, Mirshahidi S, Ruprecht RM.Overlapping synthetic peptides as vaccines.Vaccine. 2006 Sep 11;24(37-39):6356-65.