DF/HCC Program Affiliation

Research Abstract

Publications

• Sulkowski MS, Mehta SH, Torbenson M, Afdhal NH, Mirel L, Moore RD, Thomas DL.Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus.AIDS 2005 Mar 24;19(6):585-92.
  15802977
• Graham CS, Curry M, He Q, Afdhal N, Nunes D, Fleming C, Horsburgh R, Craven D, Sherman KE, Koziel MJ.Comparison of HCV-specific intrahepatic CD4+ T cells in HIV/HCV versus HCV.Hepatology 2004 Jul;40(1):125-32.
  15239095
• Wang HH, Afdhal NH, Wang DQ.Estrogen receptor alpha, but not beta, plays a major role in 17beta-estradiol-induced murine cholesterol gallstones.Gastroenterology 2004 Jul;127(1):239-49.
  15236189
• Afdhal NH, Dieterich DT, Pockros PJ, Schiff ER, Shiffman ML, Sulkowski MS, Wright T, Younossi Z, Goon BL, Tang KL, Bowers PJ,.Epoetin alfa maintains ribavirin dose in HCV-infected patients: a prospective, double-blind, randomized controlled study.Gastroen
  15131791
• Afdhal NH, Cao X, Bansil R, Hong Z, Thompson C, Brown B, Wolf D.Interaction of mucin with cholesterol enriched vesicles: role of mucin structural domains.Biomacromolecules 2004 Mar-Apr;5(2):269-75.
  15002984
• Yang C, Zeisberg M, Lively JC, Nyberg P, Afdhal N, Kalluri R.Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment.Cancer Res 2003 Dec 1;63(23):8312-7.
  14678990
• Yang C, Zeisberg M, Mosterman B, Sudhakar A, Yerramalla U, Holthaus K, Xu L, Eng F, Afdhal N, Kalluri R.Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors.Gastroenterology 2003 Jan;124(
  12512039
• Manning DS, Afdhal NH.Diagnosis and quantitation of fibrosis.Gastroenterology 2008 May;134(6):1670-81.
  18471546
• Schuppan D, Afdhal NH.Liver cirrhosis.Lancet 2008 Mar 8;371(9615):838-51.
  18328931
• Zinkin NT, Grall F, Bhaskar K, Otu HH, Spentzos D, Kalmowitz B, Wells M, Guerrero M, Asara JM, Libermann TA, Afdhal NH.Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease.Clin Cancer Res 2008 Jan 15;14(2):470-7.
  18223221
• Patel K, Nelson DR, Rockey DC, Afdhal NH, Smith KM, Oh E, Hettinger K, Vallee M, Dev A, Smith-Riggs M, McHutchison JG.Correlation of FIBROSpect II with histologic and morphometric evaluation of liver fibrosis in chronic hepatitis C.Clin Gastroenterol Hepa
  18187364
• Lai M, Afdhal N, Challies T.Liver masses and eosinophilia.Liver Int 2008 Jan;28(1):150.
  18173566
• Afdhal NH, McHutchison JG.Review article: pharmacological approaches for the treatment of thrombocytopenia in patients with chronic liver disease and hepatitis C infection.Aliment Pharmacol Ther 2007 Nov;26 Suppl 1:29-39.
  17958517
• Afdhal NH, Esteban R.Introduction: thrombocytopenia in chronic liver disease -- treatment implications and novel approaches.Aliment Pharmacol Ther 2007 Nov;26 Suppl 1:1-4.
  17958513
• McHutchison JG, Dusheiko G, Shiffman ML, Rodriguez-Torres M, Sigal S, Bourliere M, Berg T, Gordon SC, Campbell FM, Theodore D, Blackman N, Jenkins J, Afdhal NH.Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C.N Engl
  18046027
• Cardenas A, Lowe R, Oh S, Bodkin S, Kenney T, Lamorte WW, Afdhal NH.Hemodynamic effects of substance P and its receptor antagonist RP67580 in anesthetized rats with carbon tetrachloride-induced cirrhosis.Scand J Gastroenterol 2007 Oct 16:1-6.
  17943634
• McHutchison JG, Bacon BR, Gordon SC, Lawitz E, Shiffman M, Afdhal NH, Jacobson IM, Muir A, Al-Adhami M, Morris ML, Lekstrom-Himes JA, Efler SM, Davis HL.Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepati
  17929306
• Lai M, Hyatt BJ, Nasser I, Curry M, Afdhal NH.The clinical significance of persistently normal ALT in chronic hepatitis B infection.J Hepatol 2007 Dec;47(6):760-7.
  17928090
• Malik R, Afdhal N.Stiffness and impedance: the new liver biomarkers.Clin Gastroenterol Hepatol 2007 Oct;5(10):1144-6.
  17916542
• Jacobson IM, Brown RS Jr, Freilich B, Afdhal N, Kwo PY, Santoro J, Becker S, Wakil AE, Pound D, Godofsky E, Strauss R, Bernstein D, Flamm S, Pauly MP, Mukhopadhyay P, Griffel LH, Brass CA.Peginterferon alfa-2b and weight-based or flat-dose ribavirin in ch
  17894303
• Pockros PJ, Schiff ER, Shiffman ML, McHutchison JG, Gish RG, Afdhal NH, Makhviladze M, Huyghe M, Hecht D, Oltersdorf T, Shapiro DA.Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C.
  17654603
• Byrnes V, Shi H, Kiryu S, Rofsky NM, Afdhal NH.The clinical outcome of small (<20 mm) arterially enhancing nodules on MRI in the cirrhotic liver.Am J Gastroenterol 2007 Aug;102(8):1654-9.
  17521396
• Mueller S, Afdhal NH, Schuppan D.Iron, HCV, and liver cancer: hard metal setting the pace?.Gastroenterology 2006 Jun;130(7):2229-34.
  16762645
• Kamal SM, Fouly AE, Kamel RR, Hockenjos B, Al Tawil A, Khalifa KE, He Q, Koziel MJ, El Naggar KM, Rasenack J, Afdhal NH.Peginterferon alfa-2b therapy in acute hepatitis C: impact of onset of therapy on sustained virologic response.Gastroenterology 2006 Ma
  16530503
• Gish RG, Afdhal NH, Dieterich DT, Reddy KR.Management of hepatitis C virus in special populations: Patient and treatment considerations.Clin Gastroenterol Hepatol 2005 Apr;3(4):311-8.
  15822034
• Kelleher TB, Afdhal N.Maintenance therapy for chronic hepatitis C.Curr Gastroenterol Rep 2005 Feb;7(1):50-3.
  15701299
• Tanamly MD, Tadros F, Labeeb S, Makld H, Shehata M, Mikhail N, Abdel-Hamid M, Shehata M, Abu-Baki L, Medhat A, Magder LS, Afdhal NH, Strickland GT.Randomised double-blinded trial evaluating silymarin for chronic hepatitis C in an Egyptian village: study d
  15571006
• Pockros PJ, Shiffman ML, Schiff ER, Sulkowski MS, Younossi Z, Dieterich DT, Wright TL, Mody SH, Tang KL, Goon BL, Bowers PJ, Leitz G, Afdhal NH,.Epoetin alfa improves quality of life in anemic HCV-infected patients receiving combination therapy.Hepatology
  15565613
• Durante-Mangoni E, Wang R, Shaulov A, He Q, Nasser I, Afdhal N, Koziel MJ, Exley MA.Hepatic CD1d expression in hepatitis C virus infection and recognition by resident proinflammatory CD1d-reactive T cells.J Immunol 2004 Aug 1;173(3):2159-66.
  15265953
• Wang DQ, Afdhal NH.Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes.Curr Gastroenterol Rep 2004 Apr;6(2):140-50.
  15191694
• Afdhal NH, Nunes D.Evaluation of liver fibrosis: a concise review.Am J Gastroenterol 2004 Jun;99(6):1160-74.
  15180741
• Wang HH, Afdhal NH, Gendler SJ, Wang DQ.Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice.Am J Physiol Gastrointest Liver Physiol 2004 Sep;287(3):G547-54.
  15075252
• Wang HH, Afdhal NH, Gendler SJ, Wang DQ.Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation.J Lipid Res 2004 Mar;45(3):438-47.
  14703511
• O'Brien MJ, Keating NM, Elderiny S, Cerda S, Keaveny AP, Afdhal NH, Nunes DP.An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C.Am J Clin Pathol 2000 Nov;114(5):712-8.
  11068544
• Stefan AM, Coulter S, Gray B, LaMorte W, Nikelaeson S, Edge AS, Afdhal NH.Xenogeneic transplantation of porcine hepatocytes into the CCl4 cirrhotic rat model.Cell Transplant 1999 Nov-Dec;8(6):649-59.
  10701494