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David J. Sugarbaker, MD


  • Hamaji M, Vanderlaan PA, Sugarbaker DJ, McNamee CJ.A microthymoma and no germinal centre in myasthenia gravis.European Journal Of Cardio Thoracic Surgery : Official Journal Of The European Association For Cardio Thoracic Surgery. 2013 Apr 15.
  • Rusch V, Baldini EH, Bueno R, De Perrot M, Flores R, Hasegawa S, Klepetko W, Krug L, Lang-Lazdunski L, Pass H, Weder W, Sugarbaker DJ, .The role of surgical cytoreduction in the treatment of malignant pleural mesothelioma: meeting summary of the International Mesothelioma Interest Group Congress, September 11-14, 2012, Boston, Mass.J Thorac Cardiovasc Surg. 2013 Apr;145(4):909-10.
  • Sugarbaker DJ, Gill RR, Yeap BY, Wolf AS, DaSilva MC, Baldini EH, Bueno R, Richards WG.Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection.J Thorac Cardiovasc Surg. 2013 Apr;145(4):955-63.
  • Sugarbaker DJ.Clinicopathologic indices can improve patient selection in malignant mesothelioma.Oncology (Huntingt). 2012 Dec;26(12):1175-6.
  • Oxman DA, Issa NC, Marty FM, Patel A, Panizales CZ, Johnson NN, Licona JH, McKenna SS, Frendl G, Mentzer SJ, Jaklitsch MT, Bueno R, Colson Y, Swanson SJ, Sugarbaker DJ, Baden LR.Postoperative Antibacterial Prophylaxis for the Prevention of Infectious Complications Associated With Tube Thoracostomy in Patients Undergoing Elective General Thoracic Surgery: A Double-blind, Placebo-Controlled, Randomized Trial.JAMA Surg. 2013 Jan 16:1-7.
  • Barbone D, Cheung P, Battula S, Busacca S, Gray SG, Longley DB, Bueno R, Sugarbaker DJ, Fennell DA, Broaddus VC.Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression.PLoS ONE. 2012;7(12):e52753.
  • Mizuguchi KA, Mitani A, Waikar SS, Ireland P, Panizales C, Deluke G, Sugarbaker DJ, Bonventre JV, Frendl G.Use of postoperative creatinine to predict sustained kidney injury in patients undergoing mesothelioma surgery.Clin J Am Soc Nephrol. 2012 Jul;7(7):1071-8.
  • Jacobson FL, Austin JH, Field JK, Jett JR, Keshavjee S, MacMahon H, Mulshine JL, Munden RF, Salgia R, Strauss GM, Sugarbaker DJ, Swanson SJ, Travis WD, Jaklitsch MT.Development of The American Association for Thoracic Surgery guidelines for low-dose computed tomography scans to screen for lung cancer in North America: recommendations of The American Association for Thoracic Surgery Task Force for Lung Cancer Screening and Surveillance.J Thorac Cardiovasc Surg. 2012 Jul;144(1):25-32.
  • Jaklitsch MT, Jacobson FL, Austin JH, Field JK, Jett JR, Keshavjee S, MacMahon H, Mulshine JL, Munden RF, Salgia R, Strauss GM, Swanson SJ, Travis WD, Sugarbaker DJ.The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups.J Thorac Cardiovasc Surg. 2012 Jul;144(1):33-8.
  • Gerbaudo VH, Mamede M, Trotman-Dickenson B, Hatabu H, Sugarbaker DJ.FDG PET/CT patterns of treatment failure of malignant pleural mesothelioma: relationship to histologic type, treatment algorithm, and survival.Eur J Nucl Med Mol Imaging. 2011 May;38(5):810-21.
  • Gee GV, Koestler DC, Christensen BC, Sugarbaker DJ, Ugolini D, Ivaldi GP, Resnick MB, Houseman EA, Kelsey KT, Marsit CJ.Downregulated microRNAs in the differential diagnosis of malignant pleural mesothelioma.Int J Cancer. 2010 Dec 15;127(12):2859-69.
  • Sugarbaker DJ, Wolf AS, Chirieac LR, Godleski JJ, Tilleman TR, Jaklitsch MT, Bueno R, Richards WG.Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy.European Journal Of Cardio Thoracic Surgery : Official Journal Of The European Association For Cardio Thoracic Surgery. 2011 Feb 8.
  • Ou WB, Hubert C, Corson JM, Bueno R, Flynn DL, Sugarbaker DJ, Fletcher JA.Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma.Neoplasia. 2011 Jan;13(1):12-22.
  • De Rienzo A, Dong L, Yeap BY, Jensen RV, Richards WG, Gordon GJ, Sugarbaker DJ, Bueno R.Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma.Clin Cancer Res. 2011 Jan 15;17(2):310-6.
  • Koestler DC, Marsit CJ, Christensen BC, Karagas MR, Bueno R, Sugarbaker DJ, Kelsey KT, Houseman EA.Semi-supervised recursively partitioned mixture models for identifying cancer subtypes.Bioinformatics. 2010 Oct 15;26(20):2578-85.
  • Wolf AS, Richards WG, Tilleman TR, Chirieac L, Hurwitz S, Bueno R, Sugarbaker DJ.Characteristics of malignant pleural mesothelioma in women.Ann Thorac Surg. 2010 Sep;90(3):949-56; discussion 956.
  • Mujoomdar AA, Tilleman TR, Richards WG, Bueno R, Sugarbaker DJ.Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: Result in a cohort of 203 resection specimens.J Thorac Cardiovasc Surg. 2010 May 29.
  • Gill RR, Umeoka S, Mamata H, Tilleman TR, Stanwell P, Woodhams R, Padera RF, Sugarbaker DJ, Hatabu H.Diffusion-weighted MRI of malignant pleural mesothelioma: preliminary assessment of apparent diffusion coefficient in histologic subtypes.AJR Am J Roentgenol. 2010 Aug;195(2):W125-30.
  • Mujoomdar AA, Tilleman TR, Richards WG, Bueno R, Sugarbaker DJ.Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: result in a cohort of 203 resection specimens.J Thorac Cardiovasc Surg. 2010 Aug;140(2):352-5.
  • Christensen BC, Houseman EA, Poage GM, Godleski JJ, Bueno R, Sugarbaker DJ, Wiencke JK, Nelson HH, Marsit CJ, Kelsey KT.Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma.Cancer Res. 2010 Jul 15;70(14):5686-94.
  • Sugarbaker DJ, Wolf AS.Surgery for malignant pleural mesothelioma.Expert Rev Respir Med. 2010 Jun;4(3):363-72. Review.
  • Bueno R, De Rienzo A, Dong L, Gordon GJ, Hercus CF, Richards WG, Jensen RV, Anwar A, Maulik G, Chirieac LR, Ho KF, Taillon BE, Turcotte CL, Hercus RG, Gullans SR, Sugarbaker DJ.Second generation sequencing of the mesothelioma tumor genome.PLoS ONE. 2010;5(5):e10612.
  • Hartman ML, Esposito JM, Yeap BY, Sugarbaker DJ.Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.J Thorac Cardiovasc Surg. 2010 May;139(5):1233-40.
  • Wolf AS, Jacobson FL, Tilleman TR, Colson Y, Richards WG, Sugarbaker DJ.Managing the pneumonectomy space after extrapleural pneumonectomy: postoperative intrathoracic pressure monitoring.European Journal Of Cardio Thoracic Surgery : Official Journal Of The European Association For Cardio Thoracic Surgery. 2010 Apr;37(4):770-5.
  • Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ.Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases.Cancer. 2010 Mar 15;116(6):1510-7.
  • Mutyala S, Stewart A, Khan AJ, Cormack RA, O'Farrell D, Sugarbaker D, Devlin PM.Permanent iodine-125 interstitial planar seed brachytherapy for close or positive margins for thoracic malignancies.Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1114-20.
  • Gee GV, Koestler DC, Christensen BC, Sugarbaker DJ, Ugolini D, Ivaldi GP, Resnick MB, Houseman EA, Kelsey KT, Marsit CJ.Downregulated MicroRNAs in the differential diagnosis of malignant pleural mesothelioma.Int J Cancer. 2010 Mar 2.
  • Dong L, Jensen RV, De Rienzo A, Gordon GJ, Xu Y, Sugarbaker DJ, Bueno R.Differentially expressed alternatively spliced genes in Malignant Pleural Mesothelioma identified using massively parallel transcriptome sequencing.BMC Med Genet. 2009;10:149.
  • Sugarbaker DJ.Multimodality management of malignant pleural mesothelioma: introduction.Semin Thorac Cardiovasc Surg. 2009;21(2):95-6.
  • Gill RR, Gerbaudo VH, Sugarbaker DJ, Hatabu H.Current trends in radiologic management of malignant pleural mesothelioma.Semin Thorac Cardiovasc Surg. 2009;21(2):111-20. Review.
  • Wolf AS, Daniel J, Sugarbaker DJ.Surgical techniques for multimodality treatment of malignant pleural mesothelioma: extrapleural pneumonectomy and pleurectomy/decortication.Semin Thorac Cardiovasc Surg. 2009;21(2):132-48. Review.
  • Caglar HB, Baldini EH, Othus M, Rabin MS, Bueno R, Sugarbaker DJ, Mentzer SJ, J√§nne PA, Johnson BE, Allen AM.Outcomes of patients with stage III nonsmall cell lung cancer treated with chemotherapy and radiation with and without surgery.Cancer. 2009 Sep 15;115(18):4156-66.
  • Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT.Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.PLoS Genet. 2009 Aug;5(8):e1000602.
  • Christensen BC, Marsit CJ, Houseman EA, Godleski JJ, Longacker JL, Zheng S, Yeh RF, Wrensch MR, Wiemels JL, Karagas MR, Bueno R, Sugarbaker DJ, Nelson HH, Wiencke JK, Kelsey KT.Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles.Cancer Res. 2009 Aug 1;69(15):6315-21.
  • Tilleman TR, Richards WG, Zellos L, Johnson BE, Jaklitsch MT, Mueller J, Yeap BY, Mujoomdar AA, Ducko CT, Bueno R, Sugarbaker DJ.Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study.J Thorac Cardiovasc Surg. 2009 Aug;138(2):405-11.
  • Krug LM,Pass HI,Rusch VW,Kindler HL,Sugarbaker DJ,Rosenzweig KE,Flores R,Friedberg JS,Pisters K,Monberg M,Obasaju CK,Vogelzang NJ.Multicenter Phase II Trial of Neoadjuvant Pemetrexed Plus Cisplatin Followed by Extrapleural Pneumonectomy and Radiation for Malignant Pleural Mesothelioma.J Clin Oncol. 2009 Jun 20;27(18):3007-13.
  • Gordon GJ,Dong L,Yeap BY,Richards WG,Glickman JN,Edenfield H,Mani M,Colquitt R,Maulik G,Van Oss B,Sugarbaker DJ,Bueno R.Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.Journal of the National Cancer Institute. 2009 May 6;101(9):678-86.
  • Zellos L,Richards WG,Capalbo L,Jaklitsch MT,Chirieac LR,Johnson BE,Bueno R,Sugarbaker DJ.A phase I study of extrapleural pneumonectomy and intracavitary intraoperative hyperthermic cisplatin with amifostine cytoprotection for malignant pleural mesothelioma.J Thorac Cardiovasc Surg. 2009 Feb;137(2):453-8.
  • Christensen BC,Houseman EA,Godleski JJ,Marsit CJ,Longacker JL,Roelofs CR,Karagas MR,Wrensch MR,Yeh RF,Nelson HH,Wiemels JL,Zheng S,Wiencke JK,Bueno R,Sugarbaker DJ,Kelsey KT.Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome.Cancer Res. 2009 Jan 1;69(1):227-34.
  • Lee JM,Pou K,Sadow PM,Chen H,Hu B,Hewison M,Adams JS,Sugarbaker DJ,Fisher ND.Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma.Endocr Pract. 2008 Nov;14(8):1011-6.
  • Strauss GM,Herndon JE 2nd,Maddaus MA,Johnstone DW,Johnson EA,Harpole DH,Gillenwater HH,Watson DM,Sugarbaker DJ,Schilsky RL,Vokes EE,Green MR.Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups.J Clin Oncol. 2008 Nov 1;26(31):5043-51.
  • Saad AG,Yeap BY,Thunnissen FB,Pinkus GS,Pinkus JL,Loda M,Sugarbaker DJ,Johnson BE,Chirieac LR.Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma.Cancer. 2008 Oct 15;113(8):2129-38.
  • Christensen BC, Godleski JJ, Marsit CJ, Houseman EA, Lopez-Fagundo CY, Longacker JL, Bueno R, Sugarbaker DJ, Nelson HH, Kelsey KT.Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma.Carcinogenesis. 2008 Aug;29(8):1555-9.
  • Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X, Naoki K, Okamoto I, Nakagawa K, Yeap BY, Meyerson M, Wong KK, Richards WG, Sugarbaker DJ, Johnson BE, J√§nne PA.Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients.Br J Cancer. 2008 Jul 22;99(2):245-52.
  • Neragi-Miandoab S,Weiner S,Sugarbaker DJ.Incidence of atrial fibrillation after extrapleural pneumonectomy vs. pleurectomy in patients with malignant pleural mesothelioma.Interact Cardiovasc Thorac Surg. 2008 Dec;7(6):1039-42.
  • Koivunen JP,Mermel C,Zejnullahu K,Murphy C,Lifshits E,Holmes AJ,Choi HG,Kim J,Chiang D,Thomas R,Lee J,Richards WG,Sugarbaker DJ,Ducko C,Lindeman N,Marcoux JP,Engelman JA,Gray NS,Lee C,Meyerson M,Janne PA.EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.Clin Cancer Res. 2008 Jul 1;14(13):4275-83.
  • Neragi-Miandoab S,Richards WG,Sugarbaker DJ.Morbidity, mortality, mean survival, and the impact of histology on survival after pleurectomy in 64 patients with malignant pleural mesothelioma.Int J Surg. 2008 Aug;6(4):293-7.
  • Christensen BC, Godleski JJ, Roelofs CR, Longacker JL, Bueno R, Sugarbaker DJ, Marsit CJ, Nelson HH, Kelsey KT.Asbestos burden predicts survival in pleural mesothelioma.Environ Health Perspect. 2008 Jun;116(6):723-6.
  • Wilson SM,Barbone D,Yang TM,Jablons DM,Bueno R,Sugarbaker DJ,Nishimura SL,Gordon GJ,Broaddus VC.mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.Am J Respir Cell Mol Biol. 2008 Nov;39(5):576-83.
  • Ettinger DS, Akerley W, Bepler G, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Feigenberg SJ, Figlin RA, Govindan R, Grannis FW Jr, Jahan T, Jahanzeb M, Kessinger A, Komaki R, Kris MG, Langer CJ, Le QT, Martins R, Otterson GA, Patel JD, Robert F, Sugarbaker DJ, Wood DE.Non-small cell lung cancer.J Natl Compr Canc Netw. 2008 Mar;6(3):228-69.
  • Neragi-Miandoab S, Linden PA, Ducko CT, Bueno R, Richards WG, Sugarbaker DJ, Jaklitsch MT.VATS pericardiotomy for patients with known malignancy and pericardial effusion: survival and prognosis of positive cytology and metastatic involvement of the pericardium: a case control study.Int J Surg. 2008 Apr;6(2):110-4.
  • Tepper J, Krasna MJ, Niedzwiecki D, Hollis D, Reed CE, Goldberg R, Kiel K, Willett C, Sugarbaker D, Mayer R.Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781.J Clin Oncol. 2008 Mar 1;26(7):1086-92.
  • Sugarbaker DJ, Richards WG, Gordon GJ, Dong L, De Rienzo A, Maulik G, Glickman JN, Chirieac LR, Hartman ML, Taillon BE, Du L, Bouffard P, Kingsmore SF, Miller NA, Farmer AD, Jensen RV, Gullans SR, Bueno R.Transcriptome sequencing of malignant pleural mesothelioma tumors.Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3521-6.
  • Allen AM, Mentzer SJ, Yeap BY, Soto R, Baldini EH, Rabin MS, Sugarbaker DJ, Bueno R.Pneumonectomy after chemoradiation: the Dana-Farber Cancer Institute/Brigham and Women's Hospital experience.Cancer. 2008 Mar 1;112(5):1106-13.
  • Gordon GJ, Mani M, Maulik G, Mukhopadhyay L, Yeap BY, Kindler HL, Salgia R, Sugarbaker DJ, Bueno R.Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.Cancer Chemother Pharmacol. 2008 Apr;61(4):549-58.
  • Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, Wang YC, Girard L, Tretiakova MS, Ahmed S, Zumba O, Soulii L, Bindokas VP, Szeto LL, Gordon GJ, Bueno R, Sugarbaker D, Lingen MW, Sattler M, Krausz T, Vigneswaran W, Natarajan V, Minna J, Vokes EE, Ferguson MK, Husain AN, Salgia R.Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.Cancer Res. 2008 Jan 1;68(1):132-42.
  • Swanson SJ, Herndon JE, D'Amico TA, Demmy TL, McKenna RJ, Green MR, Sugarbaker DJ.Video-assisted thoracic surgery lobectomy: report of CALGB 39802--a prospective, multi-institution feasibility study.J Clin Oncol. 2007 Nov 1;25(31):4993-7.
  • Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ, Hatabu H.Morphologic and functional imaging of malignant pleural mesothelioma.Eur J Radiol. 2007 Dec;64(3):356-66. Review.
  • Richards W, Van Oss S, Glickman J, Chirieac L, Yeap B, Dong L, Gordon G, Mercer H, Gill K, Imrich A, Bueno R, Sugarbaker D.A microaliquoting technique for precise histological annotation and optimization of cell content in frozen tissue specimens.Biotech Histochem. 2007 Oct 3:1-9.
  • Chang MY, Mentzer SJ, Colson YL, Linden PA, Jaklitsch MT, Lipsitz SR, Sugarbaker DJ.Factors predicting poor survival after resection of stage IA non-small cell lung cancer.J Thorac Cardiovasc Surg. 2007 Oct;134(4):850-6.
  • Sugarbaker DJ.Surgical treatment of emphysema: introduction.Semin Thorac Cardiovasc Surg. 2007 Summer;19(2):133-4.
  • Camp PC, Sugarbaker DJ.Surgical interventions for emphysema.Semin Thorac Cardiovasc Surg. 2007 Summer;19(2):157-71. Review.
  • Allen AM, Den R, Wong JS, Zurakowski D, Soto R, Jšnne PA, Zellos L, Bueno R, Sugarbaker DJ, Baldini EH.Influence of radiotherapy technique and dose on patterns of failure for mesothelioma patients after extrapleural pneumonectomy.Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1366-74.
  • Loewen GM, Watson D, Kohman L, Herndon JE, Shennib H, Kernstine K, Olak J, Mador MJ, Harpole D, Sugarbaker D, Green M,.Preoperative exercise Vo2 measurement for lung resection candidates: results of Cancer and Leukemia Group B Protocol 9238.J Thorac Oncol. 2007 Jul;2(7):619-25.
  • Paul S, Ramanathan T, Cohen DM, Lebenthal A, Zellos L, Aranki SF, Sugarbaker DJ.Primary Ewing sarcoma invading the heart: resection and reconstruction.J Thorac Cardiovasc Surg. 2007 Jun;133(6):1667-9.
  • Sugarbaker DJ.Macroscopic complete resection: the goal of primary surgery in multimodality therapy for pleural mesothelioma.J Thorac Oncol. 2006 Feb;1(2):175-6. Review.
  • Linden PA, Bueno R, Mentzer SJ, Zellos L, Lebenthal A, Colson YL, Sugarbaker DJ, Jaklitsch MT.Modified T-tube repair of delayed esophageal perforation results in a low mortality rate similar to that seen with acute perforations.Ann Thorac Surg. 2007 Mar;83(3):1129-33.
  • Li Y, Chang Q, Rubin BP, Fletcher CD, Morgan TW, Mentzer SJ, Sugarbaker DJ, Fletcher JA, Xiao S.Insulin receptor activation in solitary fibrous tumours.J Pathol. 2007 Apr;211(5):550-4.
  • Stewart AJ, O'Farrell DA, Mutyala S, Bueno R, Sugarbaker DJ, Cormack RA, Devlin PM.Severe toxicity after permanent radioactive seed implantation for mediastinal carcinoid tumors.Brachytherapy. 2007 Jan-Mar;6(1):58-61.
  • Linden PA, Yeap BY, Chang MY, Henderson WG, Jaklitsch MT, Khuri S, Sugarbaker DJ, Bueno R.Morbidity of lung resection after prior lobectomy: results from the Veterans Affairs National Surgical Quality Improvement Program.Ann Thorac Surg. 2007 Feb;83(2):425-31; discussion 432.
  • Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Edenfield HR, Glickman JN, Yeap BY, Sugarbaker DJ, Bueno R.Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma.J Pathol. 2007 Mar;211(4):447-54.
  • Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Yeap BY, Sugarbaker DJ, Bueno R.Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.J Pathol. 2007 Mar;211(4):439-46.
  • Marsit CJ, Houseman EA, Christensen BC, Eddy K, Bueno R, Sugarbaker DJ, Nelson HH, Karagas MR, Kelsey KT.Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors.Cancer Res. 2006 Nov 1;66(21):10621-9.
  • Jaklitsch MT, Herndon JE, DeCamp MM, Richards WG, Kumar P, Krasna MJ, Green MR, Sugarbaker DJ.Nodal downstaging predicts survival following induction chemotherapy for stage IIIA (N2) non-small cell lung cancer in CALGB protocol #8935.J Surg Oncol. 2006 Dec 1;94(7):599-606.
  • Ettinger DS, Bepler G, Bueno R, Chang A, Chang JY, Chirieac LR, D'Amico TA, Demmy TL, Feigenberg SJ, Grannis FW, Jahan T, Jahanzeb M, Kessinger A, Komaki R, Kris MG, Langer CJ, Le QT, Martins R, Otterson GA, Robert F, Sugarbaker DJ, Wood DE,.Non-small cell lung cancer clinical practice guidelines in oncology.J Natl Compr Canc Netw. 2006 Jul;4(6):548-82.
  • Allen AM, Czerminska M, Jšnne PA, Sugarbaker DJ, Bueno R, Harris JR, Court L, Baldini EH.Fatal pneumonitis associated with intensity-modulated radiation therapy for mesothelioma.Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):640-5.
  • Richards WG, Zellos L, Bueno R, Jaklitsch MT, Jšnne PA, Chirieac LR, Yeap BY, Dekkers RJ, Hartigan PM, Capalbo L, Sugarbaker DJ.Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesothelioma.J Clin Oncol. 2006 Apr 1;24(10):1561-7.
  • Mukhopadhyay NK, Weisberg E, Gilchrist D, Bueno R, Sugarbaker DJ, Jaklitsch MT.Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer.Ann Thorac Surg. 2006 Mar;81(3):1034-42.
  • Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, Sugarbaker DJ, Bueno R.Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation.J Thorac Cardiovasc Surg. 2006 Feb;131(2):438-46.
  • Jagadeeswaran R, Ma PC, Seiwert TY, Jagadeeswaran S, Zumba O, Nallasura V, Ahmed S, Filiberti R, Paganuzzi M, Puntoni R, Kratzke RA, Gordon GJ, Sugarbaker DJ, Bueno R, Janamanchi V, Bindokas VP, Kindler HL, Salgia R.Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.Cancer Res. 2006 Jan 1;66(1):352-61.
  • Mery CM, Pappas AN, Burt BM, Bueno R, Linden PA, Sugarbaker DJ, Jaklitsch MT.Diameter of non-small cell lung cancer correlates with long-term survival: implications for T stage.Chest. 2005 Nov;128(5):3255-60.
  • Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK.K-ras activation generates an inflammatory response in lung tumors.Oncogene. 2006 Mar 30;25(14):2105-12.
  • Mukhopadhyay NK, Gordon GJ, Maulik G, Doerre G, Liu BC, Bueno R, Sugarbaker DJ, Jaklitsch MT.Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast.J Cell Mol Med. 2005 Jul-Sep;9(3):662-9.
  • Mery CM, Pappas AN, Bueno R, Colson YL, Linden P, Sugarbaker DJ, Jaklitsch MT.Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology, and end results database.Chest. 2005 Jul;128(1):237-45.
  • Zhao X, Weir BA, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee JC, Naoki K, Richards WG, Sugarbaker D, Chen F, Rubin MA, Jšnne PA, Girard L, Minna J, Christiani D, Li C, Sellers WR, Meyerson M.Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.Cancer Res. 2005 Jul 1;65(13):5561-70.
  • Mukhopadhyay NK, Gordon GJ, Chen CJ, Bueno R, Sugarbaker DJ, Jaklitsch MT.Activation of focal adhesion kinase in human lung cancer cells involves multiple and potentially parallel signaling events.J Cell Mol Med. 2005 Apr-Jun;9(2):387-97.
  • Gordon GJ, Rockwell GN, Godfrey PA, Jensen RV, Glickman JN, Yeap BY, Richards WG, Sugarbaker DJ, Bueno R.Validation of genomics-based prognostic tests in malignant pleural mesothelioma.Clin Cancer Res. 2005 Jun 15;11(12):4406-14.
  • Linden PA, Bueno R, Colson YL, Jaklitsch MT, Lukanich J, Mentzer S, Sugarbaker DJ.Lung resection in patients with preoperative FEV1 < 35% predicted.Chest. 2005 Jun;127(6):1984-90.
  • Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R.Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.Am J Pathol. 2005 Jun;166(6):1827-40.
  • Mamon HJ, Yeap BY, Jšnne PA, Reblando J, Shrager S, Jaklitsch MT, Mentzer S, Lukanich JM, Sugarbaker DJ, Baldini EH, Berman S, Skarin A, Bueno R.High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation.J Clin Oncol. 2005 Mar 1;23(7):1530-7.
  • Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W, Sugarbaker D, Husain AN, Christensen JG, Salgia R.Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.Cancer Res. 2005 Feb 15;65(4):1479-88.
  • VanSonnenberg E, Shankar S, Morrison PR, Nair RT, Silverman SG, Jaklitsch MT, Liu F, Cheung L, Tuncali K, Skarin AT, Sugarbaker DJ.Radiofrequency ablation of thoracic lesions: part 2, initial clinical experience--technical and multidisciplinary considerations in 30 patients.AJR Am J Roentgenol. 2005 Feb;184(2):381-90.
  • Ito H, Clancy TE, Osteen RT, Swanson RS, Bueno R, Sugarbaker DJ, Ashley SW, Zinner MJ, Whang EE.Adenocarcinoma of the gastric cardia: what is the optimal surgical approach?.J Am Coll Surg. 2004 Dec;199(6):880-6.
  • Sugarbaker DJ, Jaklitsch MT, Bueno R, Richards W, Lukanich J, Mentzer SJ, Colson Y, Linden P, Chang M, Capalbo L, Oldread E, Neragi-Miandoab S, Swanson SJ, Zellos LS.Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies.J Thorac Cardiovasc Surg. 2004 Jul;128(1):138-46.
  • Mery CM, Pappas AN, Bueno R, Mentzer SJ, Lukanich JM, Sugarbaker DJ, Jaklitsch MT.Relationship between a history of antecedent cancer and the probability of malignancy for a solitary pulmonary nodule.Chest. 2004 Jun;125(6):2175-81.
  • Eltzschig HK, Sugarbaker DJ, Felbinger TW.Effusive-constrictive pericarditis.N Engl J Med. 2004 May 27;350(22):2310-2; author reply 2310.
  • Byrne JG, Leacche M, Agnihotri AK, Paul S, Bueno R, Mathisen DJ, Sugarbaker DJ.The use of cardiopulmonary bypass during resection of locally advanced thoracic malignancies: a 10-year two-center experience.Chest. 2004 Apr;125(4):1581-6.
  • Moore KA, Mery CM, Jaklitsch MT, P Estocin A, Bueno R, Swanson SJ, Sugarbaker DJ, Lukanich JM.Menopausal effects on presentation, treatment, and survival of women with non-small cell lung cancer.Ann Thorac Surg. 2003 Dec;76(6):1789-95.
  • Gerbaudo VH, Britz-Cunningham S, Sugarbaker DJ, Treves ST.Metabolic significance of the pattern, intensity and kinetics of 18F-FDG uptake in malignant pleural mesothelioma.Thorax. 2003 Dec;58(12):1077-82.
  • Chang MY, Sugarbaker DJ.Surgery for early stage non-small cell lung cancer.Semin Surg Oncol. 2003;21(2):74-84.
  • Gordon GJ, Richards WG, Sugarbaker DJ, Jaklitsch MT, Bueno R.A prognostic test for adenocarcinoma of the lung from gene expression profiling data.Cancer Epidemiol Biomarkers Prev. 2003 Sep;12(9):905-10.
  • Sugarbaker DJ.Lung cancer. 6: The case for limited surgical resection in non-small cell lung cancer.Thorax. 2003 Jul;58(7):639-41.
  • Wirth LJ, Lucca J, Ostler P, Fidias P, Lynch C, Jšnne PA, Herbst RS, Johnson BE, Sugarbaker DJ, Mathisen DJ, Lukanich JM, Choi NC, Berman SM, Skarin AT.Induction docetaxel and carboplatin followed by weekly docetaxel and carboplatin with concurrent radiotherapy, then surgery in stage III non-small cell lung cancer: a Phase I study.Clin Cancer Res. 2003 May;9(5):1698-704.
  • Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Richards WG, Jaklitsch MT, Sugarbaker DJ, Bueno R.Using gene expression ratios to predict outcome among patients with mesothelioma.J Natl Cancer Inst. 2003 Apr 16;95(8):598-605.
  • Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS.Gene expression in lung adenocarcinomas of smokers and nonsmokers.Am J Respir Cell Mol Biol. 2003 Aug;29(2):157-62.
  • Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, Fidias P, Donahue D, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Sugarbaker D, Mihm M, Dranoff G.Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.J Clin Oncol. 2003 Feb 15;21(4):624-30.
  • Powell CA, Bueno R, Borczuk AC, Caracta CF, Richards WG, Sugarbaker DJ, Brody JS.Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.Lung Cancer. 2003 Jan;39(1):23-9.
  • Byrne JG, Karavas AN, Colson YL, Bueno R, Richards WG, Sugarbaker DJ, Goldhaber SZ.Cardiac decortication (epicardiectomy) for occult constrictive cardiac physiology after left extrapleural pneumonectomy.Chest. 2002 Dec;122(6):2256-9.
  • Naoki K, Chen TH, Richards WG, Sugarbaker DJ, Meyerson M.Missense mutations of the BRAF gene in human lung adenocarcinoma.Cancer Res. 2002 Dec 1;62(23):7001-3.
  • Gerbaudo VH, Sugarbaker DJ, Britz-Cunningham S, Di Carli MF, Mauceri C, Treves ST.Assessment of malignant pleural mesothelioma with (18)F-FDG dual-head gamma-camera coincidence imaging: comparison with histopathology.J Nucl Med. 2002 Sep;43(9):1144-9.
  • Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Ramaswamy S, Richards WG, Sugarbaker DJ, Bueno R.Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma.Cancer Res. 2002 Sep 1;62(17):4963-7.
  • Zellos LS, Sugarbaker DJ.Diffuse malignant mesothelioma of the pleural space and its management.Oncology (Huntingt). 2002 Jul;16(7):907-13; discussion 916-7,.
  • Gordon GJ, Appasani K, Parcells JP, Mukhopadhyay NK, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R.Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma.Carcinogenesis. 2002 Jun;23(6):1017-24.
  • Zellos L, Sugarbaker DJ.Current surgical management of malignant pleural mesothelioma.Curr Oncol Rep. 2002 Jul;4(4):354-60.
  • Gordon GJ, Chen CJ, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R.Detection and quantification of SV40 large T-antigen DNA in mesothelioma tissues and cell lines.Oncol Rep. 2002 May-Jun;9(3):631-4.
  • Zellos LS, Sugarbaker DJ.Multimodality treatment of diffuse malignant pleural mesothelioma.Semin Oncol. 2002 Feb;29(1):41-50.
  • Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, Loda M, Weber G, Mark EJ, Lander ES, Wong W, Johnson BE, Golub TR, Sugarbaker DJ, Meyerson M.Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses.Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13790-5.
  • Krasna MJ, Reed CE, Nedzwiecki D, Hollis DR, Luketich JD, DeCamp MM, Mayer RJ, Sugarbaker DJ,.CALGB 9380: a prospective trial of the feasibility of thoracoscopy/laparoscopy in staging esophageal cancer.Ann Thorac Surg. 2001 Apr;71(4):1073-9.
  • Jaklitsch MT, Mery CM, Lukanich JM, Richards WG, Bueno R, Swanson SJ, Mentzer SJ, Davis BD, Allred EN, Sugarbaker DJ.Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest.J Thorac Cardiovasc Surg. 2001 Apr;121(4):657-67.
  • Ho L, Sugarbaker DJ, Skarin AT.Malignant pleural mesothelioma.Cancer Treat Res. 2001;105:327-73.
  • Bueno R, Richards WG, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ.Nodal stage after induction therapy for stage IIIA lung cancer determines patient survival.Ann Thorac Surg. 2000 Dec;70(6):1826-31.
  • Breathnach OS, Kwiatkowski DJ, Finkelstein DM, Godleski J, Sugarbaker DJ, Johnson BE, Mentzer S.Bronchioloalveolar carcinoma of the lung: recurrences and survival in patients with stage I disease.J Thorac Cardiovasc Surg. 2001 Jan;121(1):42-7.
  • Flores RM, Sugarbaker DJ.Malignant mesothelioma of the pleural space.Ann Thorac Surg. 2000 Jul;70(1):306.
  • Flores RM, Sugarbaker DJ.High-risk bronchoscopy.Ann Thorac Surg. 2000 May;69(5):1604-5.
  • Mallery S, DeCamp M, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ, Van Dam J.Pretreatment staging by endoscopic ultrasonography does not predict complete response to neoadjuvant chemoradiation in patients with esophageal carcinoma.Cancer. 1999 Sep 1;86(5):764-9.
  • Salgia R, Li JL, Ewaniuk DS, Wang YB, Sattler M, Chen WC, Richards W, Pisick E, Shapiro GI, Rollins BJ, Chen LB, Griffin JD, Sugarbaker DJ.Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.Oncogene. 1999 Jan 7;18(1):67-77.
  • Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ.Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients.J Thorac Cardiovasc Surg. 1999 Jan;117(1):54-63; discussion 63-5.
  • Willett CG, Smith DI, Shridhar V, Wang MH, Emanuel RL, Patidar K, Graham SA, Zhang F, Hatch V, Sugarbaker DJ, Sunday ME.Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival.J Clin Invest. 1997 Jun 15;99(12):2979-91.
  • Baldini EH, Recht A, Strauss GM, DeCamp MM, Swanson SJ, Liptay MJ, Mentzer SJ, Sugarbaker DJ.Patterns of failure after trimodality therapy for malignant pleural mesothelioma.Ann Thorac Surg. 1997 Feb;63(2):334-8.
  • Strauss GM, Kwiatkowski DJ, Harpole DH, Lynch TJ, Skarin AT, Sugarbaker DJ.Molecular and pathologic markers in stage I non-small-cell carcinoma of the lung.J Clin Oncol. 1995 May;13(5):1265-79.
  • Sugarbaker DJ, Herndon J, Kohman LJ, Krasna MJ, Green MR.Results of cancer and leukemia group B protocol 8935. A multiinstitutional phase II trimodality trial for stage IIIA (N2) non-small-cell lung cancer. Cancer and Leukemia Group B Thoracic Surgery Group.J Thorac Cardiovasc Surg. 1995 Mar;109(3):473-83; discussion 483-5.