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Barry H. Paw, MD, PhD

Publications

  • Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH.Teleost growth factor independence (gfi) genes differentially regulate succes
    22960038
  • Blanc L, Ciciotte SL, Gwynn B, Hildick-Smith GJ, Pierce EL, Soltis KA, Cooney JD, Paw BH, Peters LL.Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.Proc Natl Acad Sci U S A. 2012 Jul 24;109(3
    22773809
  • Chung J, Chen C, Paw BH.Heme metabolism and erythropoiesis.Curr Opin Hematol. 2012 Mar 7.
    22406824
  • Chen C, Paw BH.Cellular and mitochondrial iron homeostasis in vertebrates.Biochim Biophys Acta. 2012 Jan 18.
    22285816
  • Wang Y, Langer NB, Shaw GC, Yang G, Li L, Kaplan J, Paw BH, Bloomer JR.Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria.Exp Hematol. 2011 Jul;39(7):784-94.
    21627978
  • Amigo JD, Yu M, Troadec MB, Gwynn B, Cooney JD, Lambert AJ, Chi NC, Weiss MJ, Peters LL, Kaplan J, Cantor AB, Paw BH.Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis.Mol Cell Biol. 2011 Apr;31(7):1344-
    21248200
  • Troadec MB, Warner D, Wallace J, Thomas K, Spangrude GJ, Phillips J, Khalimonchuk O, Paw BH, Ward DM, Kaplan J.Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.Blood. 2011 Feb 10.
    21310927
  • Schultz IJ, Chen C, Paw BH, Hamza I.Iron and porphyrin trafficking in heme biogenesis.J Biol Chem. 2010 Aug 27;285(35):26753-9. Review.
    20522548
  • Yu D, dos Santos CO, Zhao G, Jiang J, Amigo JD, Khandros E, Dore LC, Yao Y, D'Souza J, Zhang Z, Ghaffari S, Choi J, Friend S, Tong W, Orange JS, Paw BH, Weiss MJ.miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta.Genes Dev. 20
    20679398
  • Chen W, Dailey HA, Paw BH.Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.Blood. 2010 Jul 29;116(4):628-30.
    20427704
  • Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH.The
    19729519
  • Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH.Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.Proc Natl Aca
    19805291
  • Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK.Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.C
    19656490
  • Paradkar PN,Zumbrennen KB,Paw BH,Ward DM,Kaplan J.Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2.Mol Cell Biol. 2009 Feb;29(4):1007-16.
    19075006
  • Dore LC, Amigo JD, Dos Santos CO, Zhang Z, Gai X, Tobias JW, Yu D, Klein AM, Dorman C, Wu W, Hardison RC, Paw BH, Weiss MJ.A GATA-1-regulated microRNA locus essential for erythropoiesis.Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3333-8.
    18303114
  • Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH.Mitoferrin is essential for erythroid
    16511496
  • Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, Chen O, Kaplan J, Zon LI,.Deficiency of glutaredoxin 5 reveals Fe-S clusters are require
    16110529
  • Shafizadeh E, Paw BH.Zebrafish as a model of human hematologic disorders.Curr Opin Hematol. 2004 Jul;11(4):255-61.
    15314525
  • Ackermann GE, Paw BH.Zebrafish: a genetic model for vertebrate organogenesis and human disorders.Front Biosci. 2003 Sep 1;8:d1227-53.
    12957827
  • Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, Peters LL, Chernova MN, Alper SL, Zapata A, Wickramasinghe SN, Lee MJ, Lux SE, Fritz A, Postlethwait JH, Zon LI.Cell-