DF/HCC Program Affiliation

Research Abstract

Publications

• Shin YC, Joo CH, Gack MU, Lee HR, Jung JU.Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression.Cancer Res 2008 Mar 15;68(6):1751-9.
  18339855
• Stoitzner P, Green LK, Jung JY, Price KM, Atarea H, Kivell B, Ronchese F.Inefficient presentation of tumor-derived antigen by tumor-infiltrating dendritic cells.Cancer Immunol Immunother 2008 Mar 1.
  18311487
• Lee SY, Yuk DY, Song HS, Yoon do Y, Jung JK, Moon DC, Lee BS, Hong JT.Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.Eur J Pharmacol 2008 Mar 17;582(1-3):17-25.
  18241858
• Jung JW, Reece WD.Dosimetric characterization of 142Pr glass seeds for brachytherapy.Appl Radiat Isot 2008 Apr;66(4):441-9.
  18171619
• Woo SK, Lee TS, Kim KM, Kim JY, Jung JH, Kang JH, Cheon GJ, Choi CW, Lim SM.Anesthesia condition for (18)F-FDG imaging of lung metastasis tumors using small animal PET.Nucl Med Biol 2008 Jan;35(1):143-50.
  18158953
• Kim JL, Woo JY, Lee MJ, Kim KR, Jung JP, Lee NJ, Choi SH, Kim HD, Yang I, Chung SY.Imaging findings of primary well-differentiated liposarcoma of the liver: a case report.Acta Radiol 2007 Dec;48(10):1061-5.
  18038349
• Means RE, Lang SM, Jung JU.The Kaposi's Sarcoma-Associated Herpesvirus K5 E3 Ubiquitin Ligase Modulates Targets by Multiple Molecular Mechanisms.J Virol 2007 Jun;81(12):6573-83.
  17409151
• Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU.TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.Nature 2007 Apr 19;446(7138):916-920.
  17392790
• Garcia MI, Kaserman J, Chung YH, Jung JU, Lee SH.Herpesvirus saimiri STP-A oncoprotein utilizes Src family protein tyrosine kinase and tumor necrosis factor receptor-associated factors to elicit cellular signal transduction.J Virol 2007 Mar;81(6):2663-74.
  17182673
• Li Q, Means R, Lang S, Jung JU.Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5.J Virol 2007 Mar;81(5):2117-27.
  17166914
• Cho IR, Jeong S, Jhun BH, An WG, Lee B, Kwak YT, Lee SH, Jung JU, Chung YH.Activation of non-canonical NF-kappaB pathway mediated by STP-A11, an oncoprotein of Herpesvirus saimiri.Virology 2007 Mar 1;359(1):37-45.
  17028057
• Chang H, Dittmer DP, Shin YC, Chul SY, Hong Y, Jung JU.Role of Notch signal transduction in Kaposi's sarcoma-associated herpesvirus gene expression.J Virol 2005 Nov;79(22):14371-82.
  16254371
• Lee BS, Lee SH, Feng P, Chang H, Cho NH, Jung JU.Characterization of the Kaposi's sarcoma-associated herpesvirus K1 signalosome.J Virol 2005 Oct;79(19):12173-84.
  16160144
• Chang H, Gwack Y, Kingston D, Souvlis J, Liang X, Means RE, Cesarman E, Hutt-Fletcher L, Jung JU.Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA.J Virol 2005 Apr;79(8):4651-63.
  15795251
• Lee SH, Jung JU, Means RE.'Complementing' viral infection: mechanisms for evading innate immunity.Trends Microbiol 2003 Oct;11(10):449-52.
  14557025
• Means RE, Choi JK, Nakamura H, Chung YH, Ishido S, Jung JU.Immune evasion strategies of Kaposi's sarcoma-associated herpesvirus.Curr Top Microbiol Immunol 2002;269:187-201.
  12224509
• Park J, Lee BS, Choi JK, Means RE, Choe J, Jung JU.Herpesviral protein targets a cellular WD repeat endosomal protein to downregulate T lymphocyte receptor expression.Immunity 2002 Aug;17(2):221-33.
  12196293
• Chung YH, Means RE, Choi JK, Lee BS, Jung JU.Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein activates myeloid-lineage cells to induce inflammatory cytokine production.J Virol 2002 May;76(10):4688-98.
  11967286
• Means RE, Ishido S, Alvarez X, Jung JU.Multiple endocytic trafficking pathways of MHC class I molecules induced by a Herpesvirus protein.EMBO J 2002 Apr 2;21(7):1638-49.
  11927548
• Nakamura H, Zarycki J, Sullivan JL, Jung JU.Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome.J Immunol 2001 Sep 1;167(5):2657-65.
  11509608
• Nakamura H, Li M, Zarycki J, Jung JU.Inhibition of p53 tumor suppressor by viral interferon regulatory factor.J Virol 2001 Aug;75(16):7572-82.
  11462029
• Choi J, Means RE, Damania B, Jung JU.Molecular piracy of Kaposi's sarcoma associated herpesvirus.Cytokine Growth Factor Rev 2001 Jun-Sep;12(2-3):245-57.
  11325605
• Li M, Damania B, Alvarez X, Ogryzko V, Ozato K, Jung JU.Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor.Mol Cell Biol 2000 Nov;20(21):8254-63.
  11027294
• Ishido S, Choi JK, Lee BS, Wang C, DeMaria M, Johnson RP, Cohen GB, Jung JU.Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein.Immunity 2000 Sep;13(3):365-74.
  11021534
• Choi JK, Ishido S, Jung JU.The collagen repeat sequence is a determinant of the degree of herpesvirus saimiri STP transforming activity.J Virol 2000 Sep;74(17):8102-10.
  10933720
• Lee BS, Alvarez X, Ishido S, Lackner AA, Jung JU.Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1.J Exp Med 2000 Jul 3;192(1):11-21.
  10880522
• Ishido S, Wang C, Lee BS, Cohen GB, Jung JU.Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins.J Virol 2000 Jun;74(11):5300-9.
  10799607
• Choi JK, Lee BS, Shim SN, Li M, Jung JU.Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome.J Virol 2000 Jan;74(1):436-46.
  10590133
• Schulze-Gahmen U, Jung JU, Kim SH.Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6.Structure Fold Des 1999 Mar 15;7(3):245-54.
  10368294
• Jung JU, Choi JK, Ensser A, Biesinger B.Herpesvirus saimiri as a model for gammaherpesvirus oncogenesis.Semin Cancer Biol 1999 Jun;9(3):231-9.
  10343074
• Katahira J, Strässer K, Podtelejnikov A, Mann M, Jung JU, Hurt E.The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.EMBO J 1999 May 4;18(9):2593-609.
  10228171
• Li M, MacKey J, Czajak SC, Desrosiers RC, Lackner AA, Jung JU.Identification and characterization of Kaposi's sarcoma-associated herpesvirus K8.1 virion glycoprotein.J Virol 1999 Feb;73(2):1341-9.
  9882339
• Howe AY, Jung JU, Desrosiers RC.Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2.J Virol 1998 Dec;72(12):9827-34.
  9811718
• Lee H, Guo J, Li M, Choi JK, DeMaria M, Rosenzweig M, Jung JU.Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus.Mol Cell Biol 1998 Sep;18(9):5219-28.
  9710606
• Duboise M, Guo J, Czajak S, Lee H, Veazey R, Desrosiers RC, Jung JU.A role for herpesvirus saimiri orf14 in transformation and persistent infection.J Virol 1998 Aug;72(8):6770-6.
  9658125
• Li M, Lee H, Guo J, Neipel F, Fleckenstein B, Ozato K, Jung JU.Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor.J Virol 1998 Jul;72(7):5433-40.
  9620998
• Guo J, Williams K, Duboise SM, Alexander L, Veazey R, Jung JU.Substitution of ras for the herpesvirus saimiri STP oncogene in lymphocyte transformation.J Virol 1998 May;72(5):3698-704.
  9557651
• Lee H, Veazey R, Williams K, Li M, Guo J, Neipel F, Fleckenstein B, Lackner A, Desrosiers RC, Jung JU.Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus.Nat Med 1998 Apr;4(4):435-40.
  9546789
• Duboise SM, Lee H, Guo J, Choi JK, Czajak S, Simon M, Desrosiers RC, Jung JU.Mutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri.J Virol 1998 Apr;72(4):2607-14.
  9525577
• Duboise SM, Guo J, Czajak S, Desrosiers RC, Jung JU.STP and Tip are essential for herpesvirus saimiri oncogenicity.J Virol 1998 Feb;72(2):1308-13.
  9445031
• Guo J, Duboise M, Lee H, Li M, Choi JK, Rosenzweig M, Jung JU.Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip.J Virol 1997 Sep;71(9):7092-6.
  9261442
• Alexander L, Du Z, Rosenzweig M, Jung JU, Desrosiers RC.A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation.J Virol 1997 Aug;71(8):6094-9.
  9223503
• Alexander L, Lee H, Rosenzweig M, Jung JU, Desrosiers RC.EGFP-containing vector system that facilitates stable and transient expression assays.Biotechniques 1997 Jul;23(1):64-6.
  9232229
• Lee H, Trimble JJ, Yoon DW, Regier D, Desrosiers RC, Jung JU.Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular src.J Virol 1997 May;71(5):3817-25.
  9094657
• Yoon DW, Lee H, Seol W, DeMaria M, Rosenzweig M, Jung JU.Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.Immunity 1997 May;6(5):571-82.
  9175835
• Li M, Lee H, Yoon DW, Albrecht JC, Fleckenstein B, Neipel F, Jung JU.Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin.J Virol 1997 Mar;71(3):1984-91.
  9032330
• Duboise SM, Guo J, Desrosiers RC, Jung JU.Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesviruses.Proc Natl Acad Sci U S A 1996 Oct 15;93(21):11389-94.
  8876145
• Jung JU, Desrosiers RC.Association of the viral oncoprotein STP-C488 with cellular ras.Mol Cell Biol 1995 Dec;15(12):6506-12.
  8524215
• Jung JU, Lang SM, Jun T, Roberts TM, Veillette A, Desrosiers RC.Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri.J Virol 1995 Dec;69(12):7814-22.
  7494293
• Jung JU, Lang SM, Friedrich U, Jun T, Roberts TM, Desrosiers RC, Biesinger B.Identification of Lck-binding elements in tip of herpesvirus saimiri.J Biol Chem 1995 Sep 1;270(35):20660-7.
  7544793
• Du Z, Lang SM, Sasseville VG, Lackner AA, Ilyinskii PO, Daniel MD, Jung JU, Desrosiers RC.Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys.Cell 1995 Aug 25;82(4):665-74.
  7664345
• Jung JU, Desrosiers RC.Distinct functional domains of STP-C488 of herpesvirus saimiri.Virology 1994 Nov 1;204(2):751-8.
  7941343
• Berend KR, Jung JU, Boyle TJ, DiMaio JM, Mungal SA, Desrosiers RC, Lyerly HK.Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.J Virol 1993 Oct;67(10):6317-21.
  8396687
• Jung JU, Desrosiers RC.Herpesvirus saimiri oncogene STP-C488 encodes a phosphoprotein.J Virol 1992 Mar;66(3):1777-80.
  1310780
• Woo HJ, Lotz MM, Jung JU, Mercurio AM.Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186.J Biol Chem 1991 Oct 5;266(28):18419-22.
  1917966
• Jung JU, Trimble JJ, King NW, Biesinger B, Fleckenstein BW, Desrosiers RC.Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri.Proc Natl Acad Sci U S A 1991 Aug 15;88(16):7051-5.
  1651491